Taurine—pyruvate aminotransferase

Last updated
taurine-pyruvate aminotransferase
Identifiers
EC no. 2.6.1.77
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
Search
PMC articles
PubMed articles
NCBI proteins

In enzymology, a taurine-pyruvate aminotransferase (EC 2.6.1.77) is an enzyme that catalyzes the chemical reaction.

taurine + pyruvate L-alanine + 2-sulfoacetaldehyde

Thus, the two substrates of this enzyme are taurine and pyruvate, whereas its two products are L-alanine and 2-sulfoacetaldehyde.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is taurine:pyruvate aminotransferase. This enzyme is also called Tpa. This enzyme participates in taurine and hypotaurine metabolism.

Related Research Articles

<span class="mw-page-title-main">Alanine</span> Α-amino acid that is used in the biosynthesis of proteins

Alanine (symbol Ala or A), or α-alanine, is an α-amino acid that is used in the biosynthesis of proteins. It contains an amine group and a carboxylic acid group, both attached to the central carbon atom which also carries a methyl group side chain. Consequently, its IUPAC systematic name is 2-aminopropanoic acid, and it is classified as a nonpolar, aliphatic α-amino acid. Under biological conditions, it exists in its zwitterionic form with its amine group protonated (as −NH3+) and its carboxyl group deprotonated (as −CO2−). It is non-essential to humans as it can be synthesised metabolically and does not need to be present in the diet. It is encoded by all codons starting with GC (GCU, GCC, GCA, and GCG).

<span class="mw-page-title-main">Alanine transaminase</span> Mammalian protein

Alanine transaminase (ALT) is a transaminase enzyme. It is also called alanine aminotransferase and was formerly called serum glutamate-pyruvate transaminase or serum glutamic-pyruvic transaminase (SGPT) and was first characterized in the mid-1950s by Arthur Karmen and colleagues. ALT is found in plasma and in various body tissues but is most common in the liver. It catalyzes the two parts of the alanine cycle. Serum ALT level, serum AST level, and their ratio are commonly measured clinically as biomarkers for liver health. The tests are part of blood panels.

In enzymology, a sulfoacetaldehyde acetyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a 2-aminoethylphosphonate—pyruvate transaminase is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">4-aminobutyrate transaminase</span> Class of enzymes

In enzymology, 4-aminobutyrate transaminase, also called GABA transaminase or 4-aminobutyrate aminotransferase, or GABA-T, is an enzyme that catalyzes the chemical reaction:

<span class="mw-page-title-main">Alanine—glyoxylate transaminase</span>

In enzymology, an alanine-glyoxylate transaminase is an enzyme that catalyzes the chemical reaction

In enzymology, an alanine-oxo-acid transaminase is an enzyme that catalyzes the chemical reaction

In enzymology, an alanine-oxomalonate transaminase is an enzyme that catalyzes the chemical reaction

In enzymology, an aminolevulinate transaminase is an enzyme that catalyzes the chemical reaction

In enzymology, an arginine-pyruvate transaminase is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Beta-alanine—pyruvate transaminase</span> Enzyme

In enzymology, a beta-alanine-pyruvate transaminase is an enzyme that catalyzes the chemical reaction

In enzymology, a D-amino-acid transaminase is an enzyme that catalyzes the chemical reaction:

In enzymology, a glutamine-pyruvate transaminase is an enzyme that catalyzes the chemical reaction

In enzymology, a lysine-pyruvate 6-transaminase is an enzyme that catalyzes the chemical reaction

In enzymology, a phenylalanine(histidine) transaminase is an enzyme that catalyzes the chemical reaction

In enzymology, a (R)-3-amino-2-methylpropionate—pyruvate transaminase is an enzyme that catalyzes the chemical reaction

In enzymology, a taurine-2-oxoglutarate transaminase is an enzyme that catalyzes the chemical reaction.

In enzymology, a valine-pyruvate transaminase is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">AGXT</span> Protein-coding gene in the species Homo sapiens

Serine—pyruvate aminotransferase is an enzyme that in humans is encoded by the AGXT gene.

L-tryptophan—pyruvate aminotransferase is an enzyme with systematic name L-tryptophan:pyruvate aminotransferase. This enzyme catalyses the following chemical reaction

References


    This page is based on this Wikipedia article
    Text is available under the CC BY-SA 4.0 license; additional terms may apply.
    Images, videos and audio are available under their respective licenses.