Astrobiology is a scientific field within the life and environmental sciences that studies the origins, early evolution, distribution, and future of life in the universe by investigating its deterministic conditions and contingent events. As a discipline, astrobiology is founded on the premise that life may exist beyond Earth.
A microorganism, or microbe, is an organism of microscopic size, which may exist in its single-celled form or as a colony of cells.
John Michael Crichton was an American author, screenwriter and filmmaker. His books have sold over 200 million copies worldwide, and over a dozen have been adapted into films. His literary works heavily feature technology and are usually within the science fiction, techno-thriller, and medical fiction genres. Crichton’s novels often explore human technological advancement and attempted dominance over nature, both with frequently catastrophic results; many of his works are cautionary tales, especially regarding themes of biotechnology. Several of his stories center specifically around themes of genetic modification, hybridization, paleontology and/or zoology. Many feature medical or scientific underpinnings, reflective of his own medical training and scientific background.
Sphere is a 1987 novel by Michael Crichton, his sixth novel under his own name and his sixteenth overall. It was adapted into the film Sphere in 1998.
A.I.M. is a fictional criminal organization appearing in American comic books published by Marvel Comics. Created by Stan Lee and Jack Kirby, it first appeared in Strange Tales #146. A.I.M. is primarily depicted as a think tank of brilliant scientists dedicated to world domination through technological means.
Andromeda most commonly refers to:
The Andromeda Strain is a 1971 American science fiction thriller film produced and directed by Robert Wise. Based on Michael Crichton's 1969 novel of the same name and adapted by Nelson Gidding, the film stars Arthur Hill, James Olson, Kate Reid, and David Wayne as a team of scientists who investigate a deadly organism of extraterrestrial origin. With a few exceptions, the film follows the book closely. The special effects were designed by Douglas Trumbull. The film is notable for its use of split screen in certain scenes.
Jeremy J. Stone was an American scientist who was president of the Federation of American Scientists from 1970 to 2000, where he led that organization's advocacy initiatives in arms control, human rights, and foreign policy. In 2000, he was succeeded as president by Henry Kelly. Stone continued his work at a new organization called Catalytic Diplomacy. Stone was the son of the journalist I. F. Stone.
The Andromeda Strain is a 2008 science fiction miniseries, based on the 1969 novel of the same name written by Michael Crichton about a team of scientists who investigate a deadly disease of extraterrestrial origin. The miniseries is a "reimagining" of the original novel rather than an adaptation. In addition to updating the setting to the early 21st century, the miniseries makes a great many plot and character changes from its source.
The Living Interplanetary Flight Experiment was an interplanetary mission developed by the Planetary Society. It consisted of sending selected microorganisms on a three-year interplanetary round-trip in a small capsule aboard the Russian Fobos-Grunt spacecraft in 2011, which was a failed sample-return mission to the Martian moon Phobos. The Fobos-Grunt mission failed to leave Earth orbit and was destroyed.
Microbiology is the scientific study of microorganisms, those being of unicellular (single-celled), multicellular, or acellular. Microbiology encompasses numerous sub-disciplines including virology, bacteriology, protistology, mycology, immunology, and parasitology.
The hologenome theory of evolution recasts the individual animal or plant as a community or a "holobiont" – the host plus all of its symbiotic microbes. Consequently, the collective genomes of the holobiont form a "hologenome". Holobionts and hologenomes are structural entities that replace misnomers in the context of host-microbiota symbioses such as superorganism, organ, and metagenome. Variation in the hologenome may encode phenotypic plasticity of the holobiont and can be subject to evolutionary changes caused by selection and drift, if portions of the hologenome are transmitted between generations with reasonable fidelity. One of the important outcomes of recasting the individual as a holobiont subject to evolutionary forces is that genetic variation in the hologenome can be brought about by changes in the host genome and also by changes in the microbiome, including new acquisitions of microbes, horizontal gene transfers, and changes in microbial abundance within hosts. Although there is a rich literature on binary host–microbe symbioses, the hologenome concept distinguishes itself by including the vast symbiotic complexity inherent in many multicellular hosts. For recent literature on holobionts and hologenomes published in an open access platform, see the following reference.
Germ theory denialism is the pseudoscientific belief that germs do not cause infectious disease, and that the germ theory of disease is wrong. It usually involves arguing that Louis Pasteur's model of infectious disease was wrong, and that Antoine Béchamp's was right. In fact, its origins are rooted in Béchamp's empirically disproven theory of pleomorphism. Another obsolete variation is known as terrain theory and postulates that the state of the internal environment determines if germs cause disease rather than germs being the sole cause of it.
Technovore is a supervillain appearing in American comic books published by Marvel Comics, typically as an enemy of the superhero Iron Man.
Biological warfare (BW)—also known as bacteriological warfare, or germ warfare—has had a presence in popular culture for over 100 years. Public interest in it became intense during the Cold War, especially the 1960s and '70s, and continues unabated. This article comprises a list of popular culture works referencing BW or bioterrorism, but not those pertaining to natural, or unintentional, epidemics.
Human interactions with microbes include both practical and symbolic uses of microbes, and negative interactions in the form of human, domestic animal, and crop diseases.
Shiladitya DasSarma is a molecular biologist well-known for contributions to the biology of halophilic and extremophilic microorganisms. He is a Professor in the University of Maryland Baltimore. He earned a PhD degree in biochemistry from the Massachusetts Institute of Technology and a BS degree in chemistry from Indiana University Bloomington. Prior to taking a faculty position, he conducted research at the Massachusetts General Hospital, Harvard Medical School, and Pasteur Institute, Paris.
Diagnostic microbiology is the study of microbial identification. Since the discovery of the germ theory of disease, scientists have been finding ways to harvest specific organisms. Using methods such as differential media or genome sequencing, physicians and scientists can observe novel functions in organisms for more effective and accurate diagnosis of organisms. Methods used in diagnostic microbiology are often used to take advantage of a particular difference in organisms and attain information about what species it can be identified as, which is often through a reference of previous studies. New studies provide information that others can reference so that scientists can attain a basic understanding of the organism they are examining.
Diseases, both real and fictional, play a significant role in fiction, with certain diseases like Huntington's disease and tuberculosis appearing in many books and films. Pandemic plagues threatening all human life, such as The Andromeda Strain, are among the many fictional diseases described in literature and film.
The Andromeda Evolution is a 2019 novel written by Daniel H. Wilson. It is a sequel to Michael Crichton's The Andromeda Strain, published 50 years prior in 1969. It is the nineteenth novel under Crichton's name, and the fourth novel published after Crichton's death.
