Tobacco virtovirus 1

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Tobacco virtovirus 1
Satellite tobacco mosaic virus crystal.jpg
Crystals of Tobacco virtovirus 1 grown in space. They are ca. ~1.5 mm long and ~30 times larger by volume than Earth-grown samples. [1]
Virus classification OOjs UI icon edit-ltr.svg
(unranked): Virus
Realm: Riboviria
Phylum: incertae sedis
Genus: Virtovirus
Species:
Tobacco virtovirus 1
Synonyms [2]
  • Tobacco mosaic satellite virus
  • Satellite tobacco mosaic virus
Schematic diagram of a Virtovirus particle, cross section and side view. Virtovirus virion (modified from Aumaivirus).png
Schematic diagram of a Virtovirus particle, cross section and side view.

Tobacco virtovirus 1, informally called Tobacco mosaic satellite virus, Satellite tobacco mosaic virus (STMV), or tobacco mosaic satellite virus, is a satellite virus first reported in Nicotiana glauca from southern California, U.S.. Its genome consists of linear positive-sense single-stranded RNA. [3]

The trivial genome map of satellite virus genera Virtovirus and Aumaivirus Aumaivirus+Virtovirus genome.png
The trivial genome map of satellite virus genera Virtovirus and Aumaivirus

Tobacco virtovirus 1 is a small, icosahedral plant virus which worsens the symptoms of infection by Tobacco mosaic virus (TMV). Satellite viruses are some of the smallest possible reproducing units in nature; they achieve this by relying on both the host cell and a host-virus (in this case, TMV) for the machinery necessary for them to reproduce. The entire Tobacco virtovirus 1 particle consists of 60 identical copies of a single protein (CP) that make up the viral capsid (coating), and a 1063-nucleotide single-stranded RNA genome which codes for the capsid and one other protein of unknown function. [5]

In a broader sense, the Tobacco Mosaic Virus holds distinctive properties, which primarily include how they are distributed and the range of their hosts. They can be found within Nicotious Glauna plants, which are typically located in warmer areas, such as the United States in California and the South American region in Bolivia and Argentina. Satellite viruses like the Tobacco Vitro Virus 1 tend to be commonly located in the same tobacco tree plant(N. Glauca), which can be described as a tall shrub that possesses small leaves, that show signs of viral infection through its mosaic and yellow complexion. The Satellite Tobacco Mosaic Virus also has a variety of alternative virus helpers, which include tomatoes tobacco, and peppers, but has yet to be found in alternate crop plants.

Additionally, the Tobacco Mosaic Virus has distinctive features in cells, which are particularly instances where virus crystals may form, as well as other protein bodies within unit membrane-bound structures. The membrane that surrounds these crystals contains many vesicles which allows for genome replication to take place. These specific cells that are infected with the virus are also linked to characteristic features associated with infection from the virus the Tobacco Mild Green, showing that these individual cells are twice as infected. As replication occurs between the two viruses, they are separately compartmentalized within a single cell, which has implications for how the satellite virus uses the TMGMV virus gene products like replicates. [6] [7]

Related Research Articles

<i>Tobacco mosaic virus</i> Virus affecting plants of the Solanaceae family

Tobacco mosaic virus (TMV) is a positive-sense single-stranded RNA virus species in the genus Tobamovirus that infects a wide range of plants, especially tobacco and other members of the family Solanaceae. The infection causes characteristic patterns, such as "mosaic"-like mottling and discoloration on the leaves. TMV was the first virus to be discovered. Although it was known from the late 19th century that a non-bacterial infectious disease was damaging tobacco crops, it was not until 1930 that the infectious agent was determined to be a virus. It is the first pathogen identified as a virus. The virus was crystallised by Wendell Meredith Stanley. It has a similar size to the largest synthetic molecule, known as PG5.

Cauliflower mosaic virus (CaMV) is a member of the genus Caulimovirus, one of the six genera in the family Caulimoviridae, which are pararetroviruses that infect plants. Pararetroviruses replicate through reverse transcription just like retroviruses, but the viral particles contain DNA instead of RNA.

<span class="mw-page-title-main">Satellite (biology)</span> Subviral agent which depends on a helper virus for its replication

A satellite is a subviral agent that depends on the coinfection of a host cell with a helper virus for its replication. Satellites can be divided into two major classes: satellite viruses and satellite nucleic acids. Satellite viruses, which are most commonly associated with plants, are also found in mammals, arthropods, and bacteria. They encode structural proteins to enclose their genetic material, which are therefore distinct from the structural proteins of their helper viruses. Satellite nucleic acids, in contrast, do not encode their own structural proteins, but instead are encapsulated by proteins encoded by their helper viruses. The genomes of satellites range upward from 359 nucleotides in length for satellite tobacco ringspot virus RNA (STobRV).

<span class="mw-page-title-main">Plant virus</span> Virus that affects plants

Plant viruses are viruses that affect plants. Like all other viruses, plant viruses are obligate intracellular parasites that do not have the molecular machinery to replicate without a host. Plant viruses can be pathogenic to vascular plants.

<i>Tombusviridae</i> Family of viruses

Tombusviridae is a family of single-stranded positive sense RNA plant viruses. There are three subfamilies, 17 genera, and 95 species in this family. The name is derived from Tomato bushy stunt virus (TBSV).

<i>Tobamovirus</i> Genus of viruses

Tobamovirus is a genus of positive-strand RNA viruses in the family Virgaviridae. Many plants, including tobacco, potato, tomato, and squash, serve as natural hosts. Diseases associated with this genus include: necrotic lesions on leaves. The name Tobamovirus comes from the host and symptoms of the first virus discovered.

<i>Tomato bushy stunt virus</i> Species of virus

Tomato bushy stunt virus (TBSV) is a virus of the tombusvirus family. It was first reported in tomatoes in 1935 and primarily affects vegetable crops, though it is not generally considered an economically significant plant pathogen. Depending upon the host, TBSV causes stunting of growth, leaf mottling, and deformed or absent fruit. The virus is likely to be soil-borne in the natural setting, but can also be transmitted mechanically, for example through contaminated cutting tools. TBSV has been used as a model system in virology research on the life cycle of plant viruses, particularly in experimental infections of the model host plant Nicotiana benthamiana.

<span class="mw-page-title-main">Movement protein</span>

In order for a virus to infect a plant, it must be able to move between cells so it can spread throughout the plant. Plant cell walls make this moving/spreading quite difficult and therefore, for this to occur, movement proteins must be present. A movement protein (MP) is a specific virus-encoded protein that is considered to be a general feature of plant genomes. They allow for local and systemic viral spread throughout a plant. MPs were first studied in the Tobacco Mosaic Virus (TMV) where it was found that viruses were unable to spread without the presence of a specific protein. In general, the plant viruses first, move within the cell from replication sites to the plasmodesmata (PD). Then, the virus is able to go through the PD and spread to other cells. This process is controlled through MPs. Different MPs use different mechanisms and pathways to regulate this spread of some viruses. Nearly all plants express at least one MP, while some can encode many different MPs which help with cell to cell viral transmission. They serve to increase the size exclusion limits (SEL) of plasmodesmata to allow for greater spread of the virus.

<i>Potyvirus</i> Genus of positive-strand RNA viruses in the family Potyviridae

Potyvirus is a genus of positive-strand RNA viruses in the family Potyviridae. Plants serve as natural hosts. Like begomoviruses, members of this genus may cause significant losses in agricultural, pastoral, horticultural, and ornamental crops. More than 200 species of aphids spread potyviruses, and most are from the subfamily Aphidinae. The genus contains 190 species and potyviruses account for about thirty percent of all currently known plant viruses.

<i>Cowpea chlorotic mottle virus</i> Species of virus

Cowpea chlorotic mottle virus, known by the abbreviation CCMV, is a virus that specifically infects the cowpea plant, or black-eyed pea. The leaves of infected plants develop yellow spots, hence the name "chlorotic". Similar to its "brother" virus, Cowpea mosaic virus (CPMV), CCMV is produced in high yield in plants. In the natural host, viral particles can be produced at 1–2 mg per gram of infected leaf tissue. Belonging to the bromovirus genus, cowpea chlorotic mottle virus (CCMV) is a small spherical plant virus. Other members of this genus include the brome mosaic virus (BMV) and the broad bean mottle virus (BBMV).

<i>Alfalfa mosaic virus</i> Species of virus

Alfalfa mosaic virus (AMV), also known as Lucerne mosaic virus or Potato calico virus, is a worldwide distributed phytopathogen that can lead to necrosis and yellow mosaics on a large variety of plant species, including commercially important crops. It is the only Alfamovirus of the family Bromoviridae. In 1931 Weimer J.L. was the first to report AMV in alfalfa. Transmission of the virus occurs mainly by some aphids, by seeds or by pollen to the seed.

<i>Cucumber mosaic virus</i> Species of virus

Cucumber mosaic virus (CMV) is a plant pathogenic virus in the family Bromoviridae. This virus has a worldwide distribution and a very wide host range, having the reputation of the widest host range of any known plant virus. It can be transmitted from plant to plant both mechanically by sap and by aphids in a stylet-borne fashion. It can also be transmitted in seeds and by the parasitic weeds, Cuscuta sp. (dodder).

Soil-borne wheat mosaic virus is a rod-shaped plant pathogen that can cause severe stunting and mosaic in susceptible wheat, barley and rye cultivars. The disease has often been misdiagnosed as a nutritional problem, but this has actually allowed in part for the fortuitous visual selection by breeding programs of resistant genotypes. Soil-borne wheat mosaic virus is part of the genus Furovirus. Members of this genus are characterized by rigid rod-shaped particles and positive sense RNA genomes consisting of two molecules that are packaged into separate particles that code for either replication, mobility, structure or defense against the host. The virus is spread by a fungal-like protist, Polymyxa graminis, whose asexual secondary and sexual primary cycles help the virus spread. The disease produces secondary symptoms from the root cell infection. The disease is a serious contributor to loss in crop yield.

<span class="mw-page-title-main">Virus</span> Infectious agent that replicates in cells

A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Viruses are found in almost every ecosystem on Earth and are the most numerous type of biological entity. Since Dmitri Ivanovsky's 1892 article describing a non-bacterial pathogen infecting tobacco plants and the discovery of the tobacco mosaic virus by Martinus Beijerinck in 1898, more than 11,000 of the millions of virus species have been described in detail. The study of viruses is known as virology, a subspeciality of microbiology.

<i>Bamboo mosaic virus</i> Species of virus

Bamboo mosaic virus (BaMV) is a plant pathogenic virus in the genus Potexvirus and the family Alphaflexiviridae. BaMV is a filamentous, flexuous rod, 490 nm in length and 15 nm in width. The virus has been fully sequenced and it is 6366 nucleotides long.

Soybean vein necrosis orthotospovirus is a plant pathogenic virus of soybeans. SVNV is a relatively new virus, which was discovered in Tennessee in 2008 and has recently been found in many US states from the Southeast and East coast to some western states including CA. This pathogen initially causes intraveinal chlorosis (yellowing) in leaves. This chlorosis then spreads throughout the leaf and eventually these chlorotic areas can become necrotic. It is a member of the order Bunyavirales, family Tospoviridae and genus Orthotospovirus, which is the only genus within this virus family that infects plants. Like other members of Bunyavirales, this virus is enveloped and has a negative sense single-stranded RNA (−ssRNA) genome composed of three genomic segments. It encodes proteins on the M and S segments in an ambisense manner.

Virus nanotechnology is the use of viruses as a source of nanoparticles for biomedical purposes. Viruses are made up of a genome and a capsid; and some viruses are enveloped. Most virus capsids measure between 20-500 nm in diameter. Because of their nanometer size dimensions, viruses have been considered as naturally occurring nanoparticles. Virus nanoparticles have been subject to the nanoscience and nanoengineering disciplines. Viruses can be regarded as prefabricated nanoparticles. Many different viruses have been studied for various applications in nanotechnology: for example, mammalian viruses are being developed as vectors for gene delivery, and bacteriophages and plant viruses have been used in drug delivery and imaging applications as well as in vaccines and immunotherapy intervention.

<span class="mw-page-title-main">Maize white line mosaic satellite virus</span> Species of virus

Maize white line mosaic satellite virus is a plant satellite virus. It is the only species in genus Aumaivirus, which is a member of realm Riboviria without assigned family or order. It only infects maize which is infected by Maize white line mosaic virus (MWLMV) of genus Aureusvirus.

<i>Albetovirus</i> Genus of virus

Albetovirus is a plant satellite virus genus. As a member of realm Riboviria without assigned family or order it contains just three species, Tobacco albetovirus 1, 2, and 3. The three virus species included in this genus represent satellite viruses that depend for their replication on helper viruses of the genera Alphanecrovirus or Betanecrovirus

References

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  2. Krupovic, Mart; Fischer, Matthias; Kuhn, Jens H. (15 June 2015). "To create 1 new species within: Virtovirus" (PDF). International Committee on Taxonomy of Viruses (ICTV). p. 5. Retrieved 19 June 2019.
  3. Dodds, J. A. (1998). "Satellite Tobacco Mosaic Virus". Annual Review of Phytopathology. 36: 295–310. doi:10.1146/annurev.phyto.36.1.295. PMID   15012502.
  4. NCBI: Aumaivirus (genus)
  5. "Molecular Dynamics of STMV". Beckman Institute for Advanced Science and Technology, University of Illinois.
  6. Dodds, J. A. (1998). "Satellite Tobacco Mosaic Virus". Annual Review of Phytopathology. Department of Plant Pathology, University of California Riverside, California. 36: 295–310. doi:10.1146/annurev.phyto.36.1.295. PMID   15012502.
  7. Dawson, William O. (1999). "Tobacco mosaic virus virulence and avirulence". Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. The Royal Society Publishing, The Philosophical Transactions Of the Royal Society B. 354 (1383): 645–651. doi:10.1098/rstb.1999.0416. PMC   1692533 . PMID   10212944.

Further reading