UDP-4-amino-4-deoxy-L-arabinose aminotransferase

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UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Identifiers
EC no. 2.6.1.87
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UDP-4-amino-4-deoxy-L-arabinose aminotransferase (EC 2.6.1.87, UDP-(beta-L-threo-pentapyranosyl-4-ulose diphosphate) aminotransferase, UDP-4-amino-4-deoxy-L-arabinose---oxoglutarate aminotransferase, UDP-Ara4O aminotransferase, UDP-L-Ara4N transaminase) is an enzyme with systematic name UDP-4-amino-4-deoxy-beta-L-arabinose:2-oxoglutarate aminotransferase. [1] [2] This enzyme catalyses the following chemical reaction

UDP-4-amino-4-deoxy-beta-L-arabinopyranose + 2-oxoglutarate UDP-beta-L-threo-pentapyranos-4-ulose + L-glutamate

This protein is a pyridoxal 5'-phosphate enzyme.

Related Research Articles

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Lipid IVA 4-amino-4-deoxy-L-arabinosyltransferase is an enzyme with systematic name 4-amino-4-deoxy-alpha-L-arabinopyranosyl ditrans, octacis-undecaprenyl phosphate:lipid IVA 4-amino-4-deoxy-L-arabinopyranosyltransferase. This enzyme catalyses the following chemical reaction

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References

  1. ↑ Breazeale SD, Ribeiro AA, Raetz CR (July 2003). "Origin of lipid A species modified with 4-amino-4-deoxy-L-arabinose in polymyxin-resistant mutants of Escherichia coli. An aminotransferase (ArnB) that generates UDP-4-deoxyl-L-arabinose". The Journal of Biological Chemistry. 278 (27): 24731–9. doi: 10.1074/jbc.m304043200 . PMID   12704196.
  2. ↑ Noland BW, Newman JM, Hendle J, Badger J, Christopher JA, Tresser J, Buchanan MD, Wright TA, Rutter ME, Sanderson WE, Müller-Dieckmann HJ, Gajiwala KS, Buchanan SG (November 2002). "Structural studies of Salmonella typhimurium ArnB (PmrH) aminotransferase: a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme". Structure. 10 (11): 1569–80. doi: 10.1016/s0969-2126(02)00879-1 . PMID   12429098.
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