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A rotaxane is a mechanically interlocked molecular architecture consisting of a dumbbell-shaped molecule which is threaded through a macrocycle. The two components of a rotaxane are kinetically trapped since the ends of the dumbbell are larger than the internal diameter of the ring and prevent dissociation (unthreading) of the components since this would require significant distortion of the covalent bonds.
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In chemistry, mechanically interlocked molecular architectures (MIMAs) are molecules that are connected as a consequence of their topology. This connection of molecules is analogous to keys on a keychain loop. The keys are not directly connected to the keychain loop but they cannot be separated without breaking the loop. On the molecular level, the interlocked molecules cannot be separated without the breaking of the covalent bonds that comprise the conjoined molecules; this is referred to as a mechanical bond. Examples of mechanically interlocked molecular architectures include catenanes, rotaxanes, molecular knots, and molecular Borromean rings. Work in this area was recognized with the 2016 Nobel Prize in Chemistry to Bernard L. Feringa, Jean-Pierre Sauvage, and J. Fraser Stoddart.
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References
- ↑ "William Dichtel". Arnold and Mabel Beckman Foundation. Retrieved March 9, 2017.
- ↑ "William Dichtel". Dichtel Research Profile. Northwestern University.
- ↑ "Dichtel Research Group | At the Interface of Organic and Materials Chemistry". Northwestern University.
- 1 2 "William Dichtel — MacArthur Foundation". MacArthur Foundation. Retrieved September 29, 2015.
- ↑ "John Simon Guggenheim Foundation | Will Dichtel" . Retrieved May 23, 2021.
- ↑ "Blavatnik National Awards for Young Scientists Announce 2020 Laureates". Blavatnik Family Foundation. Retrieved July 22, 2020.
- ↑ Bomgardner, Melody M. (February 22, 2019). "CycloPure raises $5 million for cyclodextrin water filtration products". cen.acs.org. Retrieved May 30, 2021.
{{cite web}}: CS1 maint: url-status (link) - 1 2 3 "John Simon Guggenheim Foundation | Will Dichtel" . Retrieved May 23, 2021.
- 1 2 "William Dichtel – Dichtel Research Group". sites.northwestern.edu. Retrieved May 23, 2021.
- ↑ Dichtel, William R.; Serin, Jason M.; Edder, Carine; Fréchet, Jean M. J.; Matuszewski, Michael; Tan, Loon-Seng; Ohulchanskyy, Tymish Y.; Prasad, Paras N. (2004). "Singlet Oxygen Generation via Two-Photon Excited FRET". Journal of the American Chemical Society. 126 (17): 5380–5381. doi:10.1021/ja031647x. ISSN 0002-7863. PMID 15113208.
- ↑ Dichtel, William R.; Hecht, Stefan; Fréchet, Jean M. J. (2005). "Functionally Layered Dendrimers: A New Building Block and Its Application to the Synthesis of Multichromophoric Light-Harvesting Systems". Organic Letters. 7 (20): 4451–4454. doi:10.1021/ol0516824. ISSN 1523-7060. PMID 16178556.
- ↑ Dichtel, William R.; Baek, Kyung-Youl; Fréchet, Jean M. J.; Rietveld, Ivo B.; Vinogradov, Sergei A. (2006). "Amphiphilic diblock star polymer catalysts via atom transfer radical polymerization". Journal of Polymer Science Part A: Polymer Chemistry. 44 (17): 4939–4951. Bibcode:2006JPoSA..44.4939D. doi:10.1002/pola.21610. ISSN 1099-0518.
- ↑ Dichtel, William R.; Miljanić, Ognjen Š.; Spruell, Jason M.; Heath, James R.; Stoddart, J. Fraser (August 1, 2006). "Efficient Templated Synthesis of Donor−Acceptor Rotaxanes Using Click Chemistry". Journal of the American Chemical Society. 128 (32): 10388–10390. doi:10.1021/ja063127i. ISSN 0002-7863. PMID 16895403.
- ↑ Dichtel, William R; Heath, James R; Fraser Stoddart, J (June 15, 2007). "Designing bistable [2]rotaxanes for molecular electronic devices". Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences. 365 (1855): 1607–1625. Bibcode:2007RSPTA.365.1607D. doi:10.1098/rsta.2007.2034. PMID 17430812. S2CID 2278747.
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