 | |
| Names | |
|---|---|
| IUPAC name Methyl N-[2-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]ethyl]carbamate | |
| Identifiers | |
3D model (JSmol) | |
| ChemSpider | |
PubChem CID | |
| UNII | |
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| Properties | |
| C16H26N2O4 | |
| Molar mass | 310.394 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Pamatolol is a beta adrenergic receptor antagonist. [1]
The Andean goose is a member of the duck, goose and swan family Anatidae. It is also known as the wallata. It is in the shelduck subfamily Tadorninae.
Sada Abe was a Japanese geisha and prostitute who murdered her lover, Kichizō Ishida, via strangulation on May 18, 1936, before cutting off his penis and testicles and carrying them around with her in her kimono. The story became a national sensation in Japan, acquiring mythic overtones, and has been interpreted by artists, philosophers, novelists and filmmakers. Abe was released after serving five years in prison and went on to write an autobiography.
In genetics, a missense mutation is a point mutation in which a single nucleotide change results in a codon that codes for a different amino acid. It is a type of nonsynonymous substitution.
Labetalol is a medication used to treat high blood pressure and in long term management of angina. This includes essential hypertension, hypertensive emergencies, and hypertension of pregnancy. In essential hypertension it is generally less preferred than a number of other blood pressure medications. It can be given by mouth or by injection into a vein.
A number of different Markov models of DNA sequence evolution have been proposed. These substitution models differ in terms of the parameters used to describe the rates at which one nucleotide replaces another during evolution. These models are frequently used in molecular phylogenetic analyses. In particular, they are used during the calculation of likelihood of a tree and they are used to estimate the evolutionary distance between sequences from the observed differences between the sequences.
Troparil is a stimulant drug used in scientific research. Troparil is a phenyltropane-based dopamine reuptake inhibitor (DRI) that is derived from methylecgonidine. Troparil is a few times more potent than cocaine as a dopamine reuptake inhibitor, but is less potent as a serotonin reuptake inhibitor, and has a duration spanning a few times longer, since the phenyl ring is directly connected to the tropane ring through a non-hydrolyzable carbon-carbon bond. The lack of an ester linkage removes the local anesthetic action from the drug, so troparil is a pure stimulant. This change in activity also makes troparil slightly less cardiotoxic than cocaine. The most commonly used form of troparil is the tartrate salt, but the hydrochloride and naphthalenedisulfonate salts are also available, as well as the free base.
RTI(-4229)-55, also called RTI-55 or iometopane, is a phenyltropane-based psychostimulant used in scientific research and in some medical applications. This drug was first cited in 1991. RTI-55 is a non-selective dopamine reuptake inhibitor derived from methylecgonidine. However, more selective analogs are derived by conversion to "pyrrolidinoamido" RTI-229, for instance. Due to the large bulbous nature of the weakly electron withdrawing iodo halogen atom, RTI-55 is the most strongly serotonergic of the simple para-substituted troparil based analogs. In rodents RTI-55 actually caused death at a dosage of 100 mg/kg, whereas RTI-51 and RTI-31 did not. Another notable observation is the strong propensity of RTI-55 to cause locomotor activity enhancements, although in an earlier study, RTI-51 was actually even stronger than RTI-55 in shifting baseline LMA. This observation serves to highlight the disparities that can arise between studies.
Abecarnil (ZK-112,119) is an anxiolytic drug from the β-Carboline family. It is one of a relatively recently developed class of medicines known as the nonbenzodiazepines, which have similar effects to the older benzodiazepine group, but with quite different chemical structures. It is a partial agonist acting selectively at the benzodiazepine site of the GABAA receptor.
Interleukin-2 receptor subunit beta is a protein that in humans is encoded by the IL2RB gene. Also known as CD122; IL15RB; P70-75.
2β-Propanoyl-3β-(2-naphthyl)-tropane or WF-23 is a cocaine analogue. It is claimed to be several hundred times more potent than cocaine at being a serotonin-norepinephrine-dopamine reuptake inhibitor.
Dichloropane ((−)-2β-Carbomethoxy-3β-(3,4-dichlorophenyl)tropane, RTI-111, O-401) is a stimulant of the phenyltropane class that acts as a serotonin–norepinephrine–dopamine reuptake inhibitor (SNDRI) with IC50 values of 3.13, 0.79 and 18 nM, respectively. In animal studies, dichloropane had a slower onset and longer duration of action compared to cocaine.
β-Bungarotoxin is a form of bungarotoxin that is fairly common in Krait venoms. It is the prototypic class of snake β-neurotoxins. There are at least five isoforms, coded β1 to β5, assembled from different combinations of A and Bchains.
A-366,833 is a drug developed by Abbott, which acts as an agonist at neural nicotinic acetylcholine receptors selective for the α4β2 subtype, and has been researched for use as an analgesic, although it has not passed clinical trials. Its structure has a nicotinonitrile (3-cyanopyridine) core bound through C5 to the N6 of (1R,5S)-3,6-diazabicyclo[3.2.0]heptane.
Bufetolol is a beta-adrenoceptor antagonist.
Sulfinalol is a beta adrenergic receptor antagonist.
γ-Tocotrienol is one of the four types of tocotrienol, a type of vitamin E.
Sada Thioub is a professional footballer who plays as a winger for Ligue 1 club Saint-Étienne, on loan from Angers. Born in France, he plays for the Senegal national team.
The South American Men's Volleyball Club Championship is an international men's club volleyball competition organized by the Confederación Sudamericana de Voleibol (CSV), the sport's governing body in South America. The competition was first contested in 2009 in Florianópolis, Brazil and tournaments have been held every year since then.
"Whole Lotta Choppas" is a song by American rapper Sada Baby. It was released on August 14, 2020, through Asylum Records, as the lead single from his upcoming debut album. The song quickly garnered popularity on the video-sharing app TikTok and became Sada Baby's first charting song. It samples Tag Team's 1993 single, "Whoomp! ". A remix featuring Nicki Minaj was released on October 16, 2020, with critical praise aimed at her appearance. The remix propelled the song to a new peak of number 35 on the Billboard Hot 100.
6-Chloronicotine is a drug which acts as an agonist at neural nicotinic acetylcholine receptors. It substitutes for nicotine in animal studies with around twice the potency, and shows antinociceptive effects.
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