CLNS1A

Last updated
CLNS1A
Protein CLNS1A PDB 1zyi.png
Identifiers
Aliases CLNS1A , CLCI, CLNS1B, ICln, chloride nucleotide-sensitive channel 1A
External IDs OMIM: 602158 MGI: 109638 HomoloGene: 990 GeneCards: CLNS1A
Orthologs
SpeciesHumanMouse
Entrez

1207

12729

Ensembl

ENSG00000074201

ENSMUSG00000025439

UniProt

P54105

Q61189
Q923F1

RefSeq (mRNA)

NM_001311202
NM_001293
NM_001311199
NM_001311200
NM_001311201

Contents

NM_023671

RefSeq (protein)

NP_001284
NP_001298128
NP_001298129
NP_001298130
NP_001298131

NP_076160

Location (UCSC) Chr 11: 77.51 – 77.64 Mb Chr 7: 97.35 – 97.37 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Methylosome subunit pICln is a protein that in humans is encoded by the CLNS1A gene. [5] [6] [7]

Interactions

CLNS1A has been shown to interact with:

See also

Related Research Articles

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<span class="mw-page-title-main">SNRPD3</span> Protein-coding gene in the species Homo sapiens

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<span class="mw-page-title-main">Protein arginine methyltransferase 5</span> Protein-coding gene in the species Homo sapiens

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<span class="mw-page-title-main">CLCN3</span> Protein-coding gene in the species Homo sapiens

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<span class="mw-page-title-main">SNRPG</span> Protein-coding gene in the species Homo sapiens

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<span class="mw-page-title-main">Syntaxin binding protein 2</span> Protein-coding gene in the species Homo sapiens

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Lin-7 homolog A is a protein that in humans is encoded by the LIN7A gene.

<span class="mw-page-title-main">Gem-associated protein 4</span> Protein-coding gene in the species Homo sapiens

Gem-associated protein 4 is a protein that in humans is encoded by the GEMIN4 gene.

<span class="mw-page-title-main">Gem-associated protein 5</span> Protein-coding gene in the species Homo sapiens

Gem-associated protein 5 is a protein that in humans is encoded by the GEMIN5 gene.

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Zinc finger protein 706 is a protein that in humans is encoded by the ZNF706 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000074201 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000025439 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ↑ Anguita J, Chalfant ML, Civan MM, Coca-Prados M (Apr 1995). "Molecular cloning of the human volume-sensitive chloride conductance regulatory protein, pICln, from ocular ciliary epithelium". Biochem Biophys Res Commun. 208 (1): 89–95. doi:10.1006/bbrc.1995.1309. PMID   7887970.
  6. ↑ Nagl UO, Erdel M, Schmarda A, Seri M, Pinggera GM, Gschwentner M, Duba C, Galietta LJ, Deetjen P, Utermann G, Paulmichl M (Mar 1997). "Chromosomal localization of the genes (CLNS1A and CLNS1B) coding for the swelling-dependent chloride channel ICln". Genomics. 38 (3): 438–41. doi:10.1006/geno.1996.0651. PMID   8975725.
  7. ↑ "Entrez Gene: CLNS1A chloride channel, nucleotide-sensitive, 1A".
  8. ↑ Larkin D, Murphy D, Reilly DF, Cahill M, Sattler E, Harriott P, Cahill DJ, Moran N (Jun 2004). "ICln, a novel integrin alphaIIbbeta3-associated protein, functionally regulates platelet activation". J. Biol. Chem. 279 (26): 27286–93. doi: 10.1074/jbc.M402159200 . PMID   15075326.
  9. 1 2 3 Friesen WJ, Paushkin S, Wyce A, Massenet S, Pesiridis GS, Van Duyne G, Rappsilber J, Mann M, Dreyfuss G (Dec 2001). "The methylosome, a 20S complex containing JBP1 and pICln, produces dimethylarginine-modified Sm proteins". Mol. Cell. Biol. 21 (24): 8289–300. doi:10.1128/MCB.21.24.8289-8300.2001. PMC   99994 . PMID   11713266.
  10. ↑ Krapivinsky G, Pu W, Wickman K, Krapivinsky L, Clapham DE (May 1998). "pICln binds to a mammalian homolog of a yeast protein involved in regulation of cell morphology". J. Biol. Chem. 273 (18): 10811–4. doi: 10.1074/jbc.273.18.10811 . PMID   9556550.
  11. ↑ Friesen WJ, Wyce A, Paushkin S, Abel L, Rappsilber J, Mann M, Dreyfuss G (Mar 2002). "A novel WD repeat protein component of the methylosome binds Sm proteins". J. Biol. Chem. 277 (10): 8243–7. doi: 10.1074/jbc.M109984200 . PMID   11756452.
  12. ↑ Krzyzanowski A, Gasper R, Adihou H, 't Hart P, Waldmann H (Feb 2021). "Biochemical Investigation of the Interaction of pICln, RioK1 and COPR5 with the PRMT5-MEP50 Complex". ChemBioChem. 22 (11): 1908–1914. doi: 10.1002/cbic.202100079 . PMC   8252068 . PMID   33624332.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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