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Hydrocortisone is the name for the hormone cortisol when supplied as a medication. Uses include conditions such as adrenocortical insufficiency, adrenogenital syndrome, high blood calcium, thyroiditis, rheumatoid arthritis, dermatitis, asthma, and COPD. It is the treatment of choice for adrenocortical insufficiency. It can be given by mouth, topically, or by injection. Stopping treatment after long-term use should be done slowly.
ATC code D07 Corticosteroids, dermatological preparations is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the WHO for the classification of drugs and other medical products. Subgroup D07 is part of the anatomical group D Dermatologicals.
Ciguatoxins are a class of toxic polycyclic polyethers found in fish that cause ciguatera.
Fludroxycortide, also known as flurandrenolide (USAN) and flurandrenolone, is a synthetic topical corticosteroid and is used as an anti-inflammatory treatment for use on skin irritations. Trade names include Haelan and Cordran.
Clobetasone (INN) is a corticosteroid used in dermatology, for treating such skin inflammation as seen in eczema, psoriasis and other forms of dermatitis, and ophthalmology. Topical clobetasone butyrate has shown minimal suppression of the Hypothalamic-pituitary-adrenal axis.
Loteprednol is a corticosteroid used to treat inflammations of the eye. It is marketed by Bausch and Lomb as Lotemax and Loterex.
Fluocinolone acetonide is a corticosteroid primarily used in dermatology to reduce skin inflammation and relieve itching. It is a synthetic hydrocortisone derivative. The fluorine substitution at position 9 in the steroid nucleus greatly enhances its activity. It was first synthesized in 1959 in the Research Department of Syntex Laboratories S.A. Mexico City. Preparations containing it were first marketed under the name Synalar. A typical dosage strength used in dermatology is 0.01–0.025%. One such cream is sold under the brand name Flucort-N and includes the antibiotic neomycin.
Prednicarbate is a relatively new topical corticosteroid drug. It is similar in potency to hydrocortisone. Compared to other topical corticosteroids, like betamethasone, repeated prednicarbate use does not cause skin atrophy as quickly. Corticosteroids have always been an important part of the pharmacological arsenal of dermatology; however, their tendency to produce side-effects has caused the need to search for new preparations.
10-Deacetylbaccatins are a series of closely related natural organic compounds isolated from the yew tree. 10-Deacetylbaccatin III is a precursor to the anti-cancer drug docetaxel (Taxotere).
Clobetasone butyrate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester.
Piperidinediones are a derivatives of piperidine with two ketone functional groups. There are six isomers, each of which has a molecular weight of 113.115 and a formula of C5H7NO2. Piperidinediones form the core structure of a variety of pharmaceutical drugs.
Critical illness-related corticosteroid insufficiency is a form of adrenal insufficiency in critically ill patients who have blood corticosteroid levels which are inadequate for the severe stress response they experience. Combined with decreased glucocorticoid receptor sensitivity and tissue response to corticosteroids, this adrenal insufficiency constitutes a negative prognostic factor for intensive care patients.
Topical steroids are the topical forms of corticosteroids. Topical steroids are the most commonly prescribed topical medications for the treatment of rash, eczema, and dermatitis. Topical steroids have anti-inflammatory properties, and are classified based on their skin vasoconstrictive abilities. There are numerous topical steroid products. All the preparations in each class have the same anti-inflammatory properties, but essentially differ in base and price.
Hydrocortisone 21-butyrate is a form of hydrocortisone butyrate.
Hydrocortisone 17-butyrate is a form of hydrocortisone butyrate.
Domoprednate is a synthetic glucocorticoid corticosteroid which was developed in the late 1970s and 1980s.
Hydrocortisone hemisuccinate (USAN), also known as hydrocortisone hydrogen succinate (BANM) or simply hydrocortisone succinate and sold under the brand name Solu-Cortel among many others, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester which is used for antiinflammatory and antiallergic indications.
