IFNA16

IFNA16
Identifiers
Aliases	IFNA16 , IFN-alphaO, IFN-alpha-16, interferon, alpha 16, interferon alpha 16
External IDs	OMIM: 147580 HomoloGene: 105364 GeneCards: IFNA16
Gene location (Human)
Chr.	Chromosome 9 (human)
End	21,217,311 bp
RNA expression pattern
	Top expressed in
	cell; ; monocyte;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	cytokine activity ; type I interferon receptor binding ; cytokine receptor binding ;
Cellular component	extracellular region ; extracellular space ;
Biological process	natural killer cell activation involved in immune response ; B cell differentiation ; defense response ; B cell proliferation ; blood coagulation ; positive regulation of peptidyl-serine phosphorylation of STAT protein ; humoral immune response ; adaptive immune response ; defense response to virus ; type I interferon signaling pathway ; response to exogenous dsRNA ; T cell activation involved in immune response ; cytokine-mediated signaling pathway ; innate immune response ; regulation of signaling receptor activity ;
	Sources:Amigo / QuickGO
Orthologs
	3449
	n/a
	ENSG00000147885
	n/a
	P05015
	n/a
	NM_002173
	n/a
	NP_002164
	n/a
	Wikidata
View/Edit Human

Last updated January 21, 2024

Interferon alpha-16, also known as IFN-alpha-16, is a protein that in humans is encoded by theIFNA16 gene.^[3]^[4]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000147885 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: interferon".
↑ Olopade OI, Bohlander SK, Pomykala H, Maltepe E, Van Melle E, Le Beau MM, Diaz MO (October 1992). "Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia". Genomics. 14 (2): 437–43. doi:10.1016/S0888-7543(05)80238-1. PMID 1385305.

Shirazi Y, Pitha PM (1993). "Interferon alpha-mediated inhibition of human immunodeficiency virus type 1 provirus synthesis in T-cells". Virology. 193 (1): 303–12. doi: 10.1006/viro.1993.1126 . PMID 8438572.
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Dianzani F, Castilletti C, Gentile M, et al. (1998). "Effects of IFN alpha on late stages of HIV-1 replication cycle". Biochimie. 80 (8–9): 745–54. doi:10.1016/S0300-9084(99)80028-5. PMID 9865497.{{cite journal}}: CS1 maint: overridden setting (link)
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Kinzl P, Otani T, Benz R, Minowada J (1997). "Interferon-alpha and -gamma differentially reduce rapid immature T-cell death by contact with HIV-1 carrier cell clones in vitro". Microbiol. Immunol. 41 (9): 709–16. doi: 10.1111/j.1348-0421.1997.tb01915.x . PMID 9343822. S2CID 85304106.
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Yang XR, Liang X, Pfeiffer RM, et al. (2010). "Associations of 9p21 variants with cutaneous malignant melanoma, nevi, and pigmentation phenotypes in melanoma-prone families with and without CDKN2A mutations". Fam. Cancer. 9 (4): 625–33. doi:10.1007/s10689-010-9356-3. PMC 3233727 . PMID 20574843.{{cite journal}}: CS1 maint: overridden setting (link)
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Gessani S, Borghi P, Fantuzzi L, et al. (1997). "Induction of cytokines by HIV-1 and its gp120 protein in human peripheral blood monocyte/macrophages and modulation of cytokine response during differentiation". J. Leukoc. Biol. 62 (1): 49–53. doi: 10.1002/jlb.62.1.49 . PMID 9225992. S2CID 31546644.{{cite journal}}: CS1 maint: overridden setting (link)
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Ankel H, Capobianchi MR, Frezza F, et al. (1996). "Interferon induction by HIV-1-infected cells: a possible role of sulfatides or related glycolipids". Virology. 221 (1): 113–9. doi: 10.1006/viro.1996.0357 . PMID 8661419.{{cite journal}}: CS1 maint: overridden setting (link)

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000147885 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-3] "Entrez Gene: interferon".

[pmid1385305-4] Olopade OI, Bohlander SK, Pomykala H, Maltepe E, Van Melle E, Le Beau MM, Diaz MO (October 1992). "Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia". Genomics. 14 (2): 437–43. doi:10.1016/S0888-7543(05)80238-1. PMID 1385305.

[1]

[2]

[3]

[4]

IFNA16

Related Research Articles

References

Further reading