**15 January** – King Francis I commissions Jean-François de Roberval to establish a French colony in New France (present-day Canada) and to propagate the Catholic faith in the territory.[2]
**March** – The Parlement of Rouen is officially reinstated following its suspension in 1540. However, Francis I maintains tight royal oversight over its proceedings.[3]
**June 15** – Anne de Montmorency, a leading noble and supporter of peace with the Holy Roman Empire, is removed from power at court. This dismissal bolsters the influence of the pro-war faction led by the Duchess of Étampes and Cardinal de Tournon.[4]
**Late 1541** – Religious reform ideas spread as the first French edition of John Calvin’s *Institutes of the Christian Religion* is published, fueling Protestant sentiment within France.[5]
**29 November** – France signs the Treaty of Fontainebleau with Denmark–Norway, establishing an alliance against the Habsburgs. Denmark agrees to place ships and troops at France's disposal in case of external aggression.[6]
**Late 1541** – The Châtellerault Edict, which extended the salt tax (gabelle) to new provinces like Angoumois and Saintonge, incites anti-tax revolts known as the “Revolt of the Pitauds” in southwestern France.[7]
Pierre Charron, French Catholic theologian and philosopher, born in France in 1541; later known for his work on skepticism and ethics. (died 1603)[8]
**Pierre de Larivey** – French dramatist and translator, born 20 July 1541; notable for bringing Italian comedy into French literature.[9]
**El Greco (Doménikos Theotokópoulos)** – Renowned painter and sculptor of the Spanish Renaissance, born in Crete in 1541 when it was part of the Republic of Venice; later became active in France and Italy.[10]
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