2-(acetamidomethylene)succinate hydrolase

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2-(acetamidomethylene)succinate hydrolase
Identifiers
EC no. 3.5.1.29
CAS no. 37289-09-1
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In enzymology, a 2-(acetamidomethylene)succinate hydrolase (EC 3.5.1.29) is an enzyme that catalyzes the chemical reaction

2-(acetamidomethylene)succinate + 2 H2O acetate + succinate semialdehyde + NH3 + CO2

Thus, the two substrates of this enzyme are 2-(acetamidomethylene)succinate and H2O, whereas its 4 products are acetate, succinate semialdehyde, NH3, and CO2.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is 2-(acetamidomethylene)succinate amidohydrolase (deaminating, decarboxylating). This enzyme is also called alpha-(N-acetylaminomethylene)succinic acid hydrolase. This enzyme participates in vitamin B6 metabolism.

Related Research Articles

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References


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