2018 Middle East respiratory syndrome outbreak

Last updated
2018 Middle East respiratory syndrome outbreak
World location map (equirectangular 180).svg
Red pog.svg
Liverpool
Red pog.svg
Seoul
Blue 000080 pog.svg
New York City
Red pog.svg Confirmed MERS cases
Blue 000080 pog.svg Suspected MERS cases
Date23 August 2018 – now
LocationConfirmed cases: Saudi Arabia, United Kingdom, South Korea
Casualties

The 2018 Middle East respiratory syndrome outbreak was a set of infections of Middle East respiratory syndrome (MERS-CoV). The cases were most numerous in, and are believed to have originated from, Saudi Arabia.

Contents

250 cases of MERS were recorded in 2017, and 249 in 2016. [3] In 2018, there was an early surge in cases, with 21 confirmed cases in February. [4] However, over the whole year, cases were down compared to previous years, with 147 recorded cases. [3]

MERS-CoV

The syndrome originates in countries on the Arabian peninsula, and there is a low general risk to any travelers. Symptoms usually appear 2 to 14 days after exposure, and include fever, cough, shortness of breath and difficulty breathing. [5]

Annual summaries

Total laboratory-confirmed cases of MERS world-wide per year were as follows: [6] [7] [8]

YearCases
201214 [8]
2013100 [8]
2014381 [8]
2015492 [7]
2016249 [7]
2017250 [7]
2018147 [7]
2019217 [6]
202061 (to June) [9]

Background of cases

On 18 June 2018, the World Health Organization (WHO) reported that there were 75 laboratory-confirmed MERS cases in Saudi Arabia. [10] The first observed case outside of the Middle East was diagnosed on 23 August 2018 in the United Kingdom, being the first case in 5 years in the country. [11] A second case was detected on 8 September 2018 of a South Korean man who was traveling from the Middle East, being the first diagnosis in that country since the 2015 outbreak. [12] There were also hundreds of suspected cases in the United States and other parts of the world, most of which were eventually diagnosed as not being MERS infections. [2] [13]

Full year totals were as follows: [7]

CountryConfirmed casesSuspected cases[ citation needed ]Deaths
Flag of Saudi Arabia.svg Saudi Arabia 145 [7]  ?41 [7]
Flag of Oman.svg Oman 1 ?0 [7]
Flag of the United Arab Emirates.svg United Arab Emirates 1 ?0 [7]
Flag of South Korea.svg South Korea 1 (travel-associated)0?0 [7]
Flag of the United Kingdom.svg United Kingdom 1 (travel-associated)0?0 [7]
Flag of the United States.svg United States 0~100?0[ citation needed ]

Response

The Ministry of Health in the Republic of Korea monitored at least 21 individuals who were in close contact with the confirmed case, and placed all identified close contacts in quarantine at their homes. [14]

World Health Organization

The confirmed case in Korea did not change the World Health Organization (WHO) overall global risk assessment for the disease, and WHO also stated that any additional confirmed cases would also not change the risk, which was deemed as low. [14] However, it does recommend countries to continue to monitor potential cases and to carefully record any unusual patterns.[ citation needed ]

European Centre for Disease Prevention and Control

After the confirmed case in the United Kingdom, the ECDC repeated their risk assessment [15] that close contacts of confirmed cases must be monitored for symptoms for at least 14 days after the last exposure. The organization also repeated that cases of the syndrome were not unexpected and had been observed in Europe before, and the risk of transmission to the general population from the confirmed case was extremely low. [16]

See also

Related Research Articles

<span class="mw-page-title-main">SARS</span> Disease caused by severe acute respiratory syndrome coronavirus

Severe acute respiratory syndrome (SARS) is a viral respiratory disease of zoonotic origin caused by the severe acute respiratory syndrome coronavirus, the first identified strain of the SARS coronavirus species, severe acute respiratory syndrome–related coronavirus (SARSr-CoV). The first known cases occurred in November 2002, and the syndrome caused the 2002–2004 SARS outbreak. In the 2010s, Chinese scientists traced the virus through the intermediary of Asian palm civets to cave-dwelling horseshoe bats in Xiyang Yi Ethnic Township, Yunnan.

<span class="mw-page-title-main">Coronavirus</span> Subfamily of viruses in the family Coronaviridae

Coronaviruses are a group of related RNA viruses that cause diseases in mammals and birds. In humans and birds, they cause respiratory tract infections that can range from mild to lethal. Mild illnesses in humans include some cases of the common cold, while more lethal varieties can cause SARS, MERS and COVID-19, which is causing the ongoing pandemic. In cows and pigs they cause diarrhea, while in mice they cause hepatitis and encephalomyelitis.

<span class="mw-page-title-main">European Centre for Disease Prevention and Control</span> Agency of the European Union

The European Centre for Disease Prevention and Control (ECDC) is an agency of the European Union (EU) whose mission is to strengthen Europe's defences against infectious diseases. It covers a wide spectrum of activities, such as: surveillance, epidemic intelligence, response, scientific advice, microbiology, preparedness, public health training, international relations, health communication, and the scientific journal Eurosurveillance.

<span class="mw-page-title-main">W. Ian Lipkin</span> Professor, microbiologist, epidemiologist

Walter Ian Lipkin is the John Snow Professor of Epidemiology at the Mailman School of Public Health at Columbia University and a professor of Neurology and Pathology at the College of Physicians and Surgeons at Columbia University. He is also director of the Center for Infection and Immunity, an academic laboratory for microbe hunting in acute and chronic diseases. Lipkin is internationally recognized for his work with West Nile virus, SARS and COVID-19.

<span class="mw-page-title-main">MERS-related coronavirus</span> Species of virus

Middle East respiratory syndrome–related coronavirus (MERS-CoV), or EMC/2012 (HCoV-EMC/2012), is the virus that causes Middle East respiratory syndrome (MERS). It is a species of coronavirus which infects humans, bats, and camels. The infecting virus is an enveloped, positive-sense, single-stranded RNA virus which enters its host cell by binding to the DPP4 receptor. The species is a member of the genus Betacoronavirus and subgenus Merbecovirus.

<span class="mw-page-title-main">Ministry of Health (Saudi Arabia)</span> Saudi Arabian ministry of Health

The Ministry of Health, commonly abbreviated to MoH, is the ministry overseeing the health care and health policy of Saudi Arabia. The ministry is tasked with formulating strategies to ensure public health in the country, while also managing crucial health infrastructure.

Novel coronavirus (nCoV) is a provisional name given to coronaviruses of medical significance before a permanent name is decided upon. Although coronaviruses are endemic in humans and infections normally mild, such as the common cold, cross-species transmission has produced some unusually virulent strains which can cause viral pneumonia and in serious cases even acute respiratory distress syndrome and death.

<span class="mw-page-title-main">MERS</span> Viral respiratory infection

Middle East respiratory syndrome (MERS) is a viral respiratory infection caused by Middle East respiratory syndrome–related coronavirus (MERS-CoV). Symptoms may range from none, to mild, to severe. Typical symptoms include fever, cough, diarrhea, and shortness of breath. The disease is typically more severe in those with other health problems.

MERS coronavirus EMC/2012 is a strain of coronavirus isolated from the sputum of the first person to become infected with what was later named Middle East respiratory syndrome–related coronavirus (MERS-CoV), a virus that causes Middle East respiratory syndrome (MERS).

London1_novel CoV/2012 is a coronavirus strain isolated from a Qatari man in London in 2012 who was one of the first patients to come down with what has since been named Middle East respiratory syndrome-related coronavirus (MERS-CoV). The Qatari patient had traveled to Saudi Arabia from Qatar. He returned to Qatar, but when he fell ill, he traveled to London for treatment. The United Kingdom's Health Protection Agency (HPA) named the virus.

<span class="mw-page-title-main">2012 Middle East respiratory syndrome outbreak</span> Epidemic of Middle East respiratory syndrome coronavirus

Since 2012, an outbreak of Middle East respiratory syndrome coronavirus has affected several countries, primarily in its namesake, the Middle East. The virus, which causes Middle East respiratory syndrome (MERS), is a novel coronavirus that was first identified in a patient from Jeddah, Saudi Arabia on June 6, 2012.

<span class="mw-page-title-main">Public health emergency of international concern</span> Formal declaration by the World Health Organization

A public health emergency of international concern (PHEIC) is a formal declaration by the World Health Organization (WHO) of "an extraordinary event which is determined to constitute a public health risk to other States through the international spread of disease and to potentially require a coordinated international response", formulated when a situation arises that is "serious, sudden, unusual, or unexpected", which "carries implications for public health beyond the affected state's national border" and "may require immediate international action". Under the 2005 International Health Regulations (IHR), states have a legal duty to respond promptly to a PHEIC. The declaration is publicized by an IHR Emergency Committee (EC) of international experts, which was developed following the 2002–2004 SARS outbreak.

The following lists events in 2014 in Saudi Arabia.

An outbreak of Middle East respiratory syndrome coronavirus occurred in South Korea from May 2015 to July 2015. The virus, which causes Middle East respiratory syndrome (MERS), was a newly emerged betacoronavirus that was first identified in a patient from Saudi Arabia in April 2012. From the outbreak, a total of 186 cases were infected in the country, with a death toll of 38.

<span class="mw-page-title-main">2016–2022 Yemen cholera outbreak</span> Outbreak of cholera in the war-torn country of Yemen

An outbreak of cholera began in Yemen in October 2016. The outbreak peaked in 2017 with over 2,000 reported deaths in that year alone. As of November 2021, there have been more than 2.5 million cases reported, and more than 4,000 people have died in the Yemen cholera outbreak, which the United Nations deemed the worst humanitarian crisis in the world at that time. However, the outbreak has substantially decreased by 2021, with a successful vaccination program implemented and only 5,676 suspected cases with two deaths reported between January 1 and March 6 of 2021.

Middle East respiratory syndrome outbreak may refer to:

The COVID-19 pandemic is the current ongoing global outbreak of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2.

Maria DeJoseph Van Kerkhove is an American infectious disease epidemiologist. With a background in high-threat pathogens, Van Kerkhove specializes in emerging and re-emerging infectious diseases and is based in the Health Emergencies Program at the World Health Organization (WHO). She is the technical lead of COVID-19 response and the head of emerging diseases and zoonosis unit at WHO.

<span class="mw-page-title-main">COVID-19 surveillance</span> Measures to monitor the spread of the respiratory disease

COVID-19 surveillance involves monitoring the spread of the coronavirus disease in order to establish the patterns of disease progression. The World Health Organization (WHO) recommends active surveillance, with focus of case finding, testing and contact tracing in all transmission scenarios. COVID-19 surveillance is expected to monitor epidemiological trends, rapidly detect new cases, and based on this information, provide epidemiological information to conduct risk assessment and guide disease preparedness.

Allison Joan McGeer is a Canadian infectious disease specialist in the Sinai Health System, and a professor in the Department of Laboratory Medicine and Pathobiology at the University of Toronto. She also appointed at the Dalla Lana School of Public Health and a Senior Clinician Scientist at the Lunenfeld-Tanenbaum Research Institute, and is a partner of the National Collaborating Centre for Infectious Diseases. McGeer has led investigations into the severe acute respiratory syndrome outbreak in Toronto and worked alongside Donald Low. During the COVID-19 pandemic, McGeer has studied how SARS-CoV-2 survives in the air and has served on several provincial committees advising aspects of the Government of Ontario's pandemic response.

References

  1. "Officials: Two flights land at PHL after passengers exhibit flu-like symptoms". www.fox29.com. 7 September 2018. Retrieved 24 January 2020.
  2. 1 2 "More flights from Middle East arrive with ill passengers". www.nbcnews.com. 7 September 2018. Retrieved 24 January 2020.
  3. 1 2 3 4 Pandemic Epidemic Diseases news: Infectious disease outbreaks reported in the Eastern Mediterranean region in 2018 Between 12 January through 31 May 2018, the National IHR Focal Point of The Kingdom of Saudi Arabia reported 75 laboratory confirmed cases of Middle East respiratory syndrome coronavirus (MERS_CoV), including twenty-three (23) deaths. Date www.emro.who.int, accessed 29 January 2020
  4. Table of Laboratory-confirmed cases in Saudi Arabia, Jan-May 2018 www.who.int, accessed 29 January 2020
  5. "IAMAT | Middle East Respiratory Syndrome". www.iamat.org. Retrieved 2018-09-13.
  6. 1 2 MERS-CoV worldwide overview Situation update, 6 December 2020 www.ecdc.europa.eu, accessed 7 February 2020
  7. 1 2 3 4 5 6 7 8 9 10 11 12 Epidemic and pandemic-prone diseases Infectious disease outbreaks reported in the Eastern Mediterranean Region in 2018 See 8. Middle East respiratory syndrome (MERS) www.emro.who.int, accessed 29 January 2020
  8. 1 2 3 4 "Rapid Risk Assessment: Middle East respiratory syndrome coronavirus (MERS-CoV) — Seventeenth update, 11 June 2015" (PDF). European Centre for Disease Prevention and Control. 11 June 2015. Retrieved 12 June 2015.
  9. "MERS coronavirus update: 61 cases reported in first half of 2020". 4 July 2020.
  10. "Middle East respiratory syndrome coronavirus (MERS-CoV) – Saudi Arabia". World Health Organization. Archived from the original on June 19, 2018. Retrieved 2018-09-13.
  11. "First case of deadly MERS virus in five years diagnosed in England". www.cnn.com. 23 August 2018. Retrieved 24 January 2020.
  12. "South Korean man infected by MERS virus, first case in 3 years". Reuters. 8 September 2018. Retrieved 24 January 2020.
  13. "South Korea searching for 50 foreigners possibly exposed to Mers". www.straitstimes.com. 11 September 2018. Retrieved 24 January 2020.
  14. 1 2 "Middle East respiratory syndrome coronavirus (MERS-CoV) infection – Republic of Korea". World Health Organization. Archived from the original on September 15, 2018. Retrieved 2018-09-13.
  15. EDCD (11 June 2015). "Rapid Risk Assessment - Middle Ease Respiratory Syndrome Coronavirus (MERS-CoV)" (PDF). EDCE Risk Assessment. 1: 1–11.
  16. "New case of MERS-CoV identified in the United Kingdom". European Centre for Disease Prevention and Control. 24 August 2018. Retrieved 2018-09-13.