Roger Federer defeated Stan Wawrinka in the final, 6–4, 7–5 to win the men's singles title at the 2017 Indian Wells Masters. It was his record-equaling fifth Indian Wells title, 25th ATP Tour Masters 1000 singles title, and 90th singles title overall.
Pablo Carreño Busta was the defending champion, but lost to Daniil Medvedev in the second round.
Fabio Fognini was the defending champion, but he chose to compete in Umag instead.
The 2021 Barcelona Open Banc Sabadell was a men's tennis tournament played on outdoor clay courts. It was the 68th edition of the event and part of the ATP Tour 500 series of the 2021 ATP Tour. It took place at the Real Club de Tenis Barcelona in Barcelona, Spain, from 19 to 25 April 2021.
Roman Safiullin was the defending champion but chose not to defend his title.
Gaël Monfils was the defending champion, but chose not to defend his title.
Aslan Karatsev won his first ATP Tour singles title, defeating Lloyd Harris in the final, 6–3, 6–2 to win the men's singles tennis title at the 2021 Dubai Tennis Championships. Karatsev became the second wildcard in the tournament's history to win the men's singles title. Harris was the first qualifier to reach the final of the Dubai Tennis Championships.
Pablo Carreño Busta defeated Jaume Munar in the final, 6–1, 2–6, 6–4 to win the inaugural Men's Singles tennis title at the 2021 Andalucía Open. Notably, this was the first tournament in ATP history to feature 4 semifinalists from the same nation.
Rafael Nadal defeated Stefanos Tsitsipas in the final, 6–4, 6–7(6–8), 7–5 to win the singles title at the 2021 Barcelona Open. Nadal saved a championship point en route to his record-extending 12th Barcelona Open title and 61st ATP Tour singles title on clay. It became the second tournament at which Nadal had earned 12 or more victories, after the French Open. At three hours and 38 minutes, the final match was also the longest best-of-three-set tour-level final ever recorded since the Association of Tennis Professionals began tracking statistics in 1991. Tsitsipas, who had also lost to Nadal in his first career ATP singles final at this tournament in 2018, was in contention to win his first ATP 500 tournament title on his seventh attempt.
The 2021 French Open – Men's Singles Qualifying is a series of tennis matches that takes place from 24 May to 28 May 2021 to determine the sixteen qualifiers into the main draw of the 2021 French Open – Men's singles, and, if necessary, the lucky losers.
The 2021 Wimbledon Championships – Men's Singles Qualifying is a series of tennis matches that was originally scheduled to take place from 21 to 24 June 2021. However, due to a heavy rain on the first day, it was rescheduled from 22 to 25 June 2021, to determine the sixteen qualifiers into the main draw of the 2021 Wimbledon Championships – Men's singles, and, if necessary, the lucky losers.
Daniil Medvedev defeated Novak Djokovic in the final, 6–4, 6–4, 6–4 to win the men's singles tennis title at the 2021 US Open. It was his first major title and he only lost one set en route, against Botic van de Zandschulp in the quarterfinals. Medvedev became the third Russian man, after Yevgeny Kafelnikov and Marat Safin, to win a major singles title and the first to do so since Safin at the 2005 Australian Open. This was Djokovic's record sixth runner-up finish at the event.
The 2021 US Open – Men's Singles Qualifying was a series of tennis matches from 24 August 2021 to 27 August 2021 where 64 players compete to determine the 16 qualifiers into the main draw of the 2021 US Open men's singles tournament, and, if necessary, the lucky losers. Due to pandemic-related restrictions, the qualifying matches were not open to the public.
The 2021 Moselle Open was a tennis tournament played on indoor hard courts. It was the 23rd edition of the Moselle Open, and part of the ATP World Tour 250 Series of the 2021 ATP Tour. It took place at the Arènes de Metz from September 20 through September 26, 2021.
Félix Auger-Aliassime defeated Stefanos Tsitsipas in the final, 6–4, 6–2. It was his maiden ATP Tour title, following eight runner-up finishes in prior finals.
Taylor Fritz defeated Rafael Nadal in the final, 6–3, 7–6(7–5) to win the men's singles tennis title at the 2022 Indian Wells Masters. It was his maiden Masters 1000 title and second career title overall. Fritz became the first American to win the title since Andre Agassi in 2001, and ended Nadal's 20-match winning streak, dating back to the 2022 Melbourne Open.
Defending champion Stefanos Tsitsipas defeated Alejandro Davidovich Fokina in the final, 6–3, 7–6(7–3) to win the singles tennis title at the 2022 Monte-Carlo Masters. He became the sixth player to win consecutive titles at the Monte-Carlo Masters in the Open Era. The win also earned him his second Masters 1000 title and his eighth career singles title overall.
Carlos Alcaraz defeated Pablo Carreño Busta in the final, 6–3, 6–2 to win the singles tennis title at the 2022 Barcelona Open. Alcaraz saved two match points in his semifinal match against Alex de Minaur. With the win, Alcaraz entered the top 10 in rankings for the first time in his career, becoming the youngest man to do so since Rafael Nadal in 2005.
The 2022 French Open – Men's singles qualifying are a series of tennis matches that takes place from 16 to 20 May 2022 to determine the sixteen qualifiers into the main draw of the 2022 French Open – Men's singles, and, if necessary, the lucky losers.
Ugo Humbert is the defending champion.
Hubert Hurkacz 
Pablo Carreño Busta 
