4-(4-Methylphenyl)-4-oxobutanoic acid

4-(4-Methylphenyl)-4-oxobutanoic acid

Names
Preferred IUPAC name 4-(4-Methylphenyl)-4-oxobutanoic acid
Other names 3-(4-Methylbenzoyl)propionic acid 3-(p-Toluoyl)propionic acid 4-(4-Methylphenyl)-4-oxobutyric acid
Identifiers
CAS Number	4619-20-9  Y
3D model (JSmol)	Interactive image
ChemSpider	213498  Y
ECHA InfoCard	100.118.705
EC Number	610-285-9
PubChem CID	244162
UNII	ZYB7JU7CMX
CompTox Dashboard (EPA)	DTXSID00288225
InChI InChI=1S/C11H12O3/c1-8-2-4-9(5-3-8)10(12)6-7-11(13)14/h2-5H,6-7H2,1H3,(H,13,14) Y Key: OEEUWZITKKSXAZ-UHFFFAOYSA-N Y InChI=1/C11H12O3/c1-8-2-4-9(5-3-8)10(12)6-7-11(13)14/h2-5H,6-7H2,1H3,(H,13,14) Key: OEEUWZITKKSXAZ-UHFFFAOYAH
SMILES O=C(c1ccc(cc1)C)CCC(=O)O
Properties
Chemical formula	C11H12O3
Molar mass	192.214 g·mol−1
Appearance	White powder
Melting point	129 °C (264 °F; 402 K)
Solubility in water	Insoluble
Hazards [1]
Occupational safety and health (OHS/OSH):
Main hazards	Flammable
GHS labelling:
Pictograms
Signal word	Warning
Hazard statements	H315, H319, H335
Precautionary statements	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P332+P313, P337+P313, P362, P403+P233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N  verify  (what is  YN ?) Infobox references

4-(4-Methylphenyl)-4-oxobutanoic acid is an organic carboxylic acid. The preparation of it is used for undergraduate teaching of organic chemistry synthesis.

Preparation

4-(4-Methylphenyl)-4-oxobutanoic acid can be prepared by a Friedel–Crafts reaction between toluene and succinic anhydride catalyzed by a Lewis acid such as aluminium chloride. ^[2]

References

1. "3-(4-Methylbenzoyl)propionic acid". pubchem.ncbi.nlm.nih.gov.
2. Preparation of 4-(p-methylphenyl)-4-oxobutanoic acid, Li Cuijuan, Lv Mingquan, Han Shuying, Xu Tanfeng (College of Chemistry and Molecule Engineering, Peking University), College Chemistry, Vol 20. Period 2.