Acute abdomen

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Acute abdomen
Specialty Gastroenterology   OOjs UI icon edit-ltr-progressive.svg

An acute abdomen refers to a sudden, severe abdominal pain. [1] It is in many cases a medical emergency, requiring urgent and specific diagnosis. Several causes need immediate surgical treatment.

Contents

Differential diagnosis

Common causes of an acute abdomen include a gastrointestinal perforation, peptic ulcer disease, mesenteric ischemia, acute cholecystitis, appendicitis, diverticulitis, pancreatitis, and an abdominal hemorrhage. However, this is a non-exhaustative list and other less common causes may also lead to an acute abdomen. [2] In pregnant patient, a tubo-ovarian abscess, ruptured ovarian cyst or a ruptured ectopic pregnancy are common causes of an acute abdomen. [2]

Ischemic acute abdomen

Vascular disorders are more likely to affect the small bowel than the large bowel. Arterial supply to the intestines is provided by the superior and inferior mesenteric arteries (SMA and IMA respectively), both of which are direct branches of the aorta. [3]

Clinically, patients present with diffuse abdominal pain, bowel distention, and bloody diarrhea. On physical exam, bowel sounds will be absent. Laboratory tests reveal a neutrophilic leukocytosis, sometimes with a left shift, and increased serum amylase. Abdominal radiography will show many air-fluid levels, as well as widespread edema. Acute ischemic abdomen is a surgical emergency. Typically, treatment involves removal of the region of the bowel that has undergone infarction, and subsequent anastomosis of the remaining healthy tissue. [4]

Diagnosis

Traditionally, the use of opiates or other pain medications in patients with an acute abdomen has been discouraged before the clinical examination because of the concern that pain medications may mask the signs and symptoms of the condition and therefore may lead to a delay in diagnosis. However, the scientific literature has shown that early administration of pain medications, including opiates, in those with acute abdomen does not lead to delayed diagnosis, delayed treatment or errors in management (the incorrect surgical treatment administered or performing un-necessary surgery). [5] [6] [2] In a meta-analysis of those with acute appendicitis, early administration of opiates was found to alter treatment approach (with a slightly higher rate of appendectomy in those who received opiates) but diagnostic accuracy and surgical outcomes were unaffected by pain medication use. [7] Clinical guidelines also recommend early analgesic use before a cause is established. [8]

Medical imaging aids in the diagnosis of potential causes of an acute abdomen. A CT scan or ultrasound of the abdomen and pelvis are the preferred imaging modalities in the evaluate of an acute abdomen. [8] The use of radiocontrast agents with CT scans improve diagnostic accuracy. [2] Some authors advocate for the use of CT angiography with contrast of the abdomen and pelvis as the preferred imaging modality. [2] An ultrasound is the preferred imaging modality in pregnant patients as CT scans expose the fetus to ionizing radiation which may lead to adverse pregnancy outcomes. [2] An abdominal x-ray may show free air in the abdominal cavity due to a perforation in the gastrointestinal tract. However, abdominal x-ray is not recommended as part of the diagnostic evaluation in acute abdomen due to its low sensitivity and specificity. [8] [2] Delays in medical imaging acquisition and interpretation greater than 2 hours are associated with an increased risk of complications and death. [2] [9]

Society and culture

In a population based study of Medicare patients in the United States, Black patients who were admitted to the hospital for an acute abdomen requiring general surgery consultation were 14% less likely to receive surgical consultation as compared to White patients. These racial disparities in care persisted (with an 11% difference) when socioeconomic factors were standardized. [10] In another population based study in the United States, Black patients and patients from other racial minority groups were 22-30% less likely to recieve pain medication for an acute abdomen as compared to White patients. [11]

Related Research Articles

<span class="mw-page-title-main">Appendicitis</span> Inflammation of the appendix

Appendicitis is inflammation of the appendix. Symptoms commonly include right lower abdominal pain, nausea, vomiting, and decreased appetite. However, approximately 40% of people do not have these typical symptoms. Severe complications of a ruptured appendix include widespread, painful inflammation of the inner lining of the abdominal wall and sepsis.

<span class="mw-page-title-main">Peritonitis</span> Inflammation of the inner wall of the abdomen (peritoneum)

Peritonitis is inflammation of the localized or generalized peritoneum, the lining of the inner wall of the abdomen and cover of the abdominal organs. Symptoms may include severe pain, swelling of the abdomen, fever, or weight loss. One part or the entire abdomen may be tender. Complications may include shock and acute respiratory distress syndrome.

<span class="mw-page-title-main">Bowel obstruction</span> Mechanical or functional obstruction of the intestines

Bowel obstruction, also known as intestinal obstruction, is a mechanical or functional obstruction of the intestines which prevents the normal movement of the products of digestion. Either the small bowel or large bowel may be affected. Signs and symptoms include abdominal pain, vomiting, bloating and not passing gas. Mechanical obstruction is the cause of about 5 to 15% of cases of severe abdominal pain of sudden onset requiring admission to hospital.

<span class="mw-page-title-main">Abdominal pain</span> Stomach aches

Abdominal pain, also known as a stomach ache, is a symptom associated with both non-serious and serious medical issues. Since the abdomen contains most of the body's vital organs, it can be an indicator of a wide variety of diseases. Given that, approaching the examination of a person and planning of a differential diagnosis is extremely important.

<span class="mw-page-title-main">Intussusception (medical disorder)</span> Folding of part of the intestine into itself

Intussusception is a medical condition in which a part of the intestine folds into the section immediately ahead of it. It typically involves the small intestine and less commonly the large intestine. Symptoms include abdominal pain which may come and go, vomiting, abdominal bloating, and bloody stool. It often results in a small bowel obstruction. Other complications may include peritonitis or bowel perforation.

<span class="mw-page-title-main">Volvulus</span> Twisting of part of the intestine, causing a bowel obstruction

A volvulus is when a loop of intestine twists around itself and the mesentery that supports it, resulting in a bowel obstruction. Symptoms include abdominal pain, abdominal bloating, vomiting, constipation, and bloody stool. Onset of symptoms may be rapid or more gradual. The mesentery may become so tightly twisted that blood flow to part of the intestine is cut off, resulting in ischemic bowel. In this situation there may be fever or significant pain when the abdomen is touched.

Intestinal malrotation is a congenital anomaly of rotation of the midgut. It occurs during the first trimester as the fetal gut undergoes a complex series of growth and development. Malrotation can lead to a dangerous complication called volvulus, in which cases emergency surgery is indicated. Malrotation can refer to a spectrum of abnormal intestinal positioning, often including:

<span class="mw-page-title-main">Gastrointestinal perforation</span> Hole in the wall of the gastrointestinal tract

Gastrointestinal perforation, also known as gastrointestinal rupture, is a hole in the wall of the gastrointestinal tract. The gastrointestinal tract is composed of hollow digestive organs leading from the mouth to the anus. Symptoms of gastrointestinal perforation commonly include severe abdominal pain, nausea, and vomiting. Complications include a painful inflammation of the inner lining of the abdominal wall and sepsis.

<span class="mw-page-title-main">Abdominal examination</span> Physical examination of abdomen

An abdominal examination is a portion of the physical examination which a physician or nurse uses to clinically observe the abdomen of a patient for signs of disease. The abdominal examination is conventionally split into four different stages: first, inspection of the patient and the visible characteristics of their abdomen. Auscultation (listening) of the abdomen with a stethoscope. Palpation of the patient's abdomen. Finally, percussion (tapping) of the patient's abdomen and abdominal organs. Depending on the need to test for specific diseases such as ascites, special tests may be performed as a part of the physical examination. An abdominal examination may be performed because the physician suspects a disease of the organs inside the abdominal cavity (including the liver, spleen, large or small intestines), or simply as a part of a complete physical examination for other conditions. In a complete physical examination, the abdominal exam classically follows the respiratory examination and cardiovascular examination.

<span class="mw-page-title-main">Nutcracker syndrome</span> Compression of the left renal vein, restricting bloodflow from the left kidney

The nutcracker syndrome (NCS) results most commonly from the compression of the left renal vein (LRV) between the abdominal aorta (AA) and superior mesenteric artery (SMA), although other variants exist. The name derives from the fact that, in the sagittal plane and/or transverse plane, the SMA and AA appear to be a nutcracker crushing a nut.

<span class="mw-page-title-main">Bowel resection</span> Surgical procedure in which a part of an intestine is removed

A bowel resection or enterectomy is a surgical procedure in which a part of an intestine (bowel) is removed, from either the small intestine or large intestine. Often the word enterectomy is reserved for the sense of small bowel resection, in distinction from colectomy, which covers the sense of large bowel resection. Bowel resection may be performed to treat gastrointestinal cancer, bowel ischemia, necrosis, or obstruction due to scar tissue, volvulus, and hernias. Some patients require ileostomy or colostomy after this procedure as alternative means of excretion. Complications of the procedure may include anastomotic leak or dehiscence, hernias, or adhesions causing partial or complete bowel obstruction. Depending on which part and how much of the intestines are removed, there may be digestive and metabolic challenges afterward, such as short bowel syndrome.

Stercoral ulcer is an ulcer of the colon due to pressure and irritation resulting from severe, prolonged constipation due to a large bowel obstruction, damage to the autonomic nervous system, or stercoral colitis. It is most commonly located in the sigmoid colon and rectum. Prolonged constipation leads to production of fecaliths, leading to possible progression into a fecaloma. These hard lumps irritate the rectum and lead to the formation of these ulcers. It results in fresh bleeding per rectum. These ulcers may be seen on imaging, such as a CT scan but are more commonly identified using endoscopy, usually a colonoscopy. Treatment modalities can include both surgical and non-surgical techniques.

<span class="mw-page-title-main">Epiploic appendagitis</span> Medical condition

Epiploic appendagitis (EA) is an uncommon, benign, self-limiting inflammatory process of the epiploic appendices. Other, older terms for the process include appendicitis epiploica and appendagitis, but these terms are used less now in order to avoid confusion with acute appendicitis.

Abdominal guarding is the tensing of the abdominal wall muscles to guard inflamed organs within the abdomen from the pain of pressure upon them. The tensing is detected when the abdominal wall is pressed. Abdominal guarding is also known as 'défense musculaire'.

<span class="mw-page-title-main">Intestinal ischemia</span> Restriction of blood flow to the small intestine resulting in injury

Intestinal ischemia is a medical condition in which injury to the large or small intestine occurs due to not enough blood supply. It can come on suddenly, known as acute intestinal ischemia, or gradually, known as chronic intestinal ischemia. The acute form of the disease often presents with sudden severe abdominal pain and is associated with a high risk of death. The chronic form typically presents more gradually with abdominal pain after eating, unintentional weight loss, vomiting, and fear of eating.

<span class="mw-page-title-main">Superior mesenteric artery syndrome</span> Pinching of the intestine between the abdominal aorta and superior mesenteric artery

Superior mesenteric artery (SMA) syndrome is a gastro-vascular disorder in which the third and final portion of the duodenum is compressed between the abdominal aorta (AA) and the overlying superior mesenteric artery. This rare, potentially life-threatening syndrome is typically caused by an angle of 6–25° between the AA and the SMA, in comparison to the normal range of 38–56°, due to a lack of retroperitoneal and visceral fat. In addition, the aortomesenteric distance is 2–8 millimeters, as opposed to the typical 10–20. However, a narrow SMA angle alone is not enough to make a diagnosis, because patients with a low BMI, most notably children, have been known to have a narrow SMA angle with no symptoms of SMA syndrome.

<span class="mw-page-title-main">Abdominal trauma</span> Medical condition

Abdominal trauma is an injury to the abdomen. Signs and symptoms include abdominal pain, tenderness, rigidity, and bruising of the external abdomen. Complications may include blood loss and infection.

<span class="mw-page-title-main">Idiopathic sclerosing mesenteritis</span> Medical condition

Idiopathic sclerosing mesenteritis (ISM) is a rare disease of the small intestine, characterized by chronic inflammation and eventual fibrosis of the mesentery. It has also been called mesenteric lipodystrophy, or retractile mesenteritis.

<span class="mw-page-title-main">Computed tomography of the abdomen and pelvis</span>

Computed tomography of the abdomen and pelvis is an application of computed tomography (CT) and is a sensitive method for diagnosis of abdominal diseases. It is used frequently to determine stage of cancer and to follow progress. It is also a useful test to investigate acute abdominal pain. Renal stones, appendicitis, pancreatitis, diverticulitis, abdominal aortic aneurysm, and bowel obstruction are conditions that are readily diagnosed and assessed with CT. CT is also the first line for detecting solid organ injury after trauma.

<span class="mw-page-title-main">Omental infarction</span> Medical condition

Omental infarction, or omental torsion, is an acute vascular disorder which compromises tissue of the greater omentum—the largest peritoneal fold in the abdomen.

References

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  2. 1 2 3 4 5 6 7 8 Rogers, Selwyn O.; Kirton, Orlando C. (4 July 2024). "Acute Abdomen in the Modern Era". New England Journal of Medicine. 391 (1): 60–67. doi:10.1056/NEJMra2304821.
  3. Skinner, Dylan; Wehrle, Chase J.; Fossen, Kelly Van (10 August 2020). "Anatomy, Abdomen and Pelvis, Inferior Mesenteric Artery". National Center for Biotechnology Information, U.S. National Library of Medicine. StatPearls Publishing LLC. PMID   29489246 . Retrieved 11 June 2021.
  4. Haglund, Ulf, M.D (2001). "Mesenteric ischemia". National Center for Biotechnology Information, U.S. National Library of Medicine. W. Zuckschwerdt Verlag GmbH. Retrieved June 13, 2021.{{cite web}}: CS1 maint: multiple names: authors list (link)
  5. Manterola, Carlos; Vial, Manuel; Moraga, Javier; Astudillo, Paula (2011-01-19). "Analgesia in patients with acute abdominal pain". Cochrane Database of Systematic Reviews (1): CD005660. doi:10.1002/14651858.cd005660.pub3. ISSN   1465-1858. PMID   21249672.
  6. Ranji SR, Goldman LE, Simel DL, Shojania KG (October 2006). "Do opiates affect the clinical evaluation of patients with acute abdominal pain?". JAMA. 296 (14): 1764–74. doi:10.1001/jama.296.14.1764. PMID   17032990.
  7. Ciarrocchi, Andrea; Amicucci, Gianfranco (November 2013). "Safety and impact on diagnostic accuracy of early analgesia in suspected acute appendicitis: A meta-analysis". International Journal of Surgery: 847–852. doi:10.1016/j.ijsu.2013.08.005.
  8. 1 2 3 Mayumi, Toshihiko; Yoshida, Masahiro; Tazuma, Susumu (January 2016). "The Practice Guidelines for Primary Care of Acute Abdomen 2015". Japanese Journal of Radiology. 34 (1): 80–115. doi:10.1007/s11604-015-0489-z.
  9. Ricci, Kevin B.; Oslock, Wendelyn M.; Ingraham, Angela M.; Rushing, Amy P.; Diaz, Adrian; Paredes, Anghela Z.; Daniel, Vijaya T.; Collins, Courtney E.; Heh, Victor K.; Baselice, Holly E.; Strassels, Scott A.; Caterino, Jeffrey M.; Santry, Heena P. (May 2021). "Importance of Radiologists in Optimizing Outcomes for Older Americans with Acute Abdomen". Journal of Surgical Research. 261: 361–368. doi:10.1016/j.jss.2020.12.022.
  10. Roberts, Sanford E.; Rosen, Claire B.; Keele, Luke J.; Wirtalla, Christopher J.; Syvyk, Solomiya; Kaufman, Elinore J.; Reilly, Patrick M.; Neuman, Mark D.; McHugh, Matthew D.; Kelz, Rachel R. (1 December 2022). "Rates of Surgical Consultations After Emergency Department Admission in Black and White Medicare Patients". JAMA Surgery. 157 (12): 1097. doi:10.1001/jamasurg.2022.4959. PMC   9558057 .
  11. Shah, Adil A.; Zogg, Cheryl K.; Zafar, Syed Nabeel (December 2015). "Analgesic Access for Acute Abdominal Pain in the Emergency Department Among Racial/Ethnic Minority Patients: A Nationwide Examination". Medical Care. 53 (12): 1000–1009. doi:10.1097/MLR.0000000000000444.