Brendan Frey

Last updated
Brendan Frey
Born
Brendan John Frey

(1968-08-29) 29 August 1968 (age 55)
Alma mater
Known for
Awards
Scientific career
Fields
Institutions
Thesis Graphical Models for Machine Learning and Digital Communication  (1997)
Doctoral advisor Geoffrey Hinton [4] [5]
Website www.psi.toronto.edu/~frey/

Brendan John Frey FRSC [2] (born 29 August 1968) is a Canadian-born entrepreneur, engineer and scientist. He is Founder and CEO of Deep Genomics, [6] Cofounder of the Vector Institute for Artificial Intelligence [6] and Professor of Engineering and Medicine at the University of Toronto. [7] Frey is a pioneer in the development of machine learning and artificial intelligence methods, their use in accurately determining the consequences of genetic mutations, and in designing medications that can slow, stop or reverse the progression of disease. [2]

Contents

As far back as 1995, Frey co-invented one of the first deep learning methods, called the wake-sleep algorithm, the affinity propagation algorithm for clustering and data summarization, and the factor graph notation for probability models. In the late 1990s, Frey was a leading researcher in the areas of computer vision, speech recognition, and digital communications.

In 2002, a personal crisis led Frey to face the fact that there was a tragic gap between our ability to measure a patient's mutations and our ability to understand and treat the consequences. Recognizing that biology is too complex for humans to understand, that in the decades to come there would be an exponential growth in biology data, and that machine learning is the best technology we have for discovering relationships in large datasets, Frey set out to build machine learning systems that could accurately predict genome and cell biology.

Frey’s group pioneered much of the early work in the field and over the next 15 years published more papers in leading-edge journals than any other academic or industrial research lab.

In 2015, Frey founded Deep Genomics, with the goal of building a company that can produce effective and safe genetic medicines more rapidly and with a higher rate of success than was previously possible. [8] [9] [10]

The company has received 240 million dollars in funding to date from leading Bay Area investors, including the backers of SpaceX and Tesla. [11] [12]

Education

Frey studied computer engineering and physics at the University of Calgary (BSc 1990) and the University of Manitoba (MSc 1993), and then studied neural networks and graphical models as a doctoral candidate at the University of Toronto under the supervision of Geoffrey Hinton (PhD 1997). He was an invited participant of the Machine Learning program at the Isaac Newton Institute for Mathematical Sciences in Cambridge, UK (1997) and was a Beckman Fellow at the University of Illinois at Urbana Champaign (1999). [1]

Career

Following his undergraduate studies, Frey worked as a junior research scientist at Bell-Northern Research from 1990 to 1991. [13] After completing his postdoctoral studies at the University of Illinois at Urbana-Champaign, Frey was an assistant professor in the Department of Computer Science at the University of Waterloo, from 1999 to 2001. [1]

In 2001, Frey joined the Department of Electrical and Computer Engineering at the University of Toronto and was cross-appointed to the Department of Computer Science, the Banting and Best Department of Medical Research and the Terrence Donnelly Centre for Cellular and Biomolecular Research. From 2008 to 2009, he was a visiting researcher at Microsoft Research (Cambridge, UK) and a visiting professor in the Cavendish Laboratories and Darwin College at Cambridge University. [7] Between 2001 and 2014, Frey consulted for several groups at Microsoft Research and acted as a member of its Technical Advisory Board. [7]

Related Research Articles

<span class="mw-page-title-main">University of Illinois Urbana-Champaign</span> Public university in Illinois, United States

The University of Illinois Urbana-Champaign is a public land-grant research university in Champaign, Illinois, and Urbana, Illinois. It is the flagship institution of the University of Illinois system and was founded in 1867. With over 53,000 students, the University of Illinois is one of the largest public universities by enrollment in the United States.

<span class="mw-page-title-main">Geoffrey Hinton</span> British-Canadian computer scientist and psychologist (born 1947)

Geoffrey Everest Hinton is a British-Canadian computer scientist and cognitive psychologist, most noted for his work on artificial neural networks. From 2013 to 2023, he divided his time working for Google and the University of Toronto, before publicly announcing his departure from Google in May 2023, citing concerns about the risks of artificial intelligence (AI) technology. In 2017, he co-founded and became the chief scientific advisor of the Vector Institute in Toronto.

Engineering physics, or engineering science, refers to the study of the combined disciplines of physics, mathematics, chemistry, biology, and engineering, particularly computer, nuclear, electrical, electronic, aerospace, materials or mechanical engineering. By focusing on the scientific method as a rigorous basis, it seeks ways to apply, design, and develop new solutions in engineering.

<span class="mw-page-title-main">Beckman Institute for Advanced Science and Technology</span>

The Beckman Institute for Advanced Science and Technology is a unit of the University of Illinois Urbana-Champaign dedicated to interdisciplinary research. A gift from scientist, businessman, and philanthropist Arnold O. Beckman (1900–2004) and his wife Mabel (1900–1989) led to the building of the Institute which opened in 1989. It is one of five institutions which receive support from the Arnold and Mabel Beckman Foundation on an ongoing basis. Current research at Beckman involves the areas of molecular engineering, intelligent systems, and imaging science. Researchers in these areas work across traditional academic boundaries in scientific projects that can lead to the development of real-world applications in medicine, industry, electronics, and human health across the lifespan.

Huimin Zhao is the Steven L. Miller Chair Professor of Chemical and Biomolecular Engineering at the University of Illinois, Urbana-Champaign, as well as the leader of the Biosystems Design research theme in the Carl R. Woese Institute for Genomic Biology. His research focuses on directed evolution, metabolic engineering, bioinformatics and high throughput technologies.

The Centre for Applied Genomics is a genome centre in the Research Institute of The Hospital for Sick Children, and is affiliated with the University of Toronto. TCAG also operates as a Science and Technology Innovation Centre of Genome Canada, with an emphasis on next-generation sequencing (NGS) and bioinformatics support. Research at TCAG focuses on the genetic and genomic basis of human variability, health and disease, including research on the genetics of autism spectrum disorder and structural variation of the human genome. The centre is located in the Peter Gilgan Centre for Research and Learning in downtown Toronto, Canada.

Jack Y. Yang is an American computer scientist and biophysicist. As of 2011, he is the editor-in-chief of the International Journal of Computational Biology and Drug Design.

<span class="mw-page-title-main">Frank Kschischang</span> Canadian academic

Frank R. Kschischang (born 15 September 1962 in Mettmann, West Germany is a professor in the Department of Electrical and Computer Engineering at the University of Toronto, and holds a Canada Research Chair in communication algorithms. He is a co-inventor of the factor graph, a kind of graphical model used in Bayesian inference.

Ravishankar K. Iyer is the George and Ann Fisher Distinguished Professor of Engineering at the University of Illinois at Urbana-Champaign. He is a specialist in reliable and secure networks and systems.

The Carl R. Woese Institute for Genomic Biology (IGB) is an interdisciplinary facility for genomics research at the University of Illinois Urbana-Champaign. The Institute was built in 2006 to centralize biotechnology research at the University of Illinois. Current research at the IGB explores the genomic bases of a wide range of phenomena, including the progression of cancer, the ecological impact of global change, tissue and organ growth, and the diversity of animal behavior.

<span class="mw-page-title-main">Lawrence B. Schook</span>

Lawrence B. Schook is the vice president for research at the University of Illinois. He oversees the $1 billion research portfolio across all three campuses. A scholar in comparative genomics and the exploitation of genomic diversity to understand traits and disease, Dr. Schook focuses his research on genetic resistance to disease, regenerative medicine, and using genomics to create animal models for biomedical research. He led the international pig genome-sequencing project, which produced a draft of the pig genome allowing researchers to offer insights into diseases that afflict pigs and humans.

<span class="mw-page-title-main">Fei-Fei Li</span> Chinese American computer scientist (born 1976)

Fei-Fei Li is a China-born American computer scientist, known for establishing ImageNet, the dataset that enabled rapid advances in computer vision in the 2010s. She is Sequoia Capital professor of computer science at Stanford University and former board director at Twitter. Li is a co-director of the Stanford Institute for Human-Centered Artificial Intelligence and a co-director of the Stanford Vision and Learning Lab. She served as the director of the Stanford Artificial Intelligence Laboratory from 2013 to 2018.

A Beckman Fellow receives funding, usually via an intermediary institution, from the Arnold and Mabel Beckman Foundation, founded by Arnold Orville Beckman and his wife Mabel. The Foundation supports programs at several institutions to encourage research, particularly the work of young researchers who might not be eligible for other sources of funding. People from a variety of different programs at different institutions may therefore be referred to as Beckman Fellows. Though most often designating postdoctoral awards in science, the exact significance of the term will vary depending on the institution involved and the type(s) of Beckman Fellowship awarded at that institution.

Brenda Jean Andrews is a Canadian academic, researcher and biologist specializing in systems biology and molecular genetics.

Klaus-Robert Müller is a German computer scientist and physicist, most noted for his work in machine learning and brain–computer interfaces.

Paris Smaragdis is a computer scientist noted for his contributions to audio signal processing, computer audition, and machine learning. He is currently an associate professor of computer science at the University of Illinois at Urbana-Champaign, Illinois. He currently holds over 35 patents in the areas of audio signal processing and machine learning.

Maryellen L. Giger, is an American physicist and radiologist who has made significant contributions to the field of medical imaging.

Marzyeh Ghassemi is a Canada-based researcher in the field of computational medicine, where her research focuses on developing machine-learning algorithms to inform health-care decisions. She is currently an assistant professor at the University of Toronto's Department of Computer Science and Faculty of Medicine, and is a Canada CIFAR Artificial Intelligence (AI) chair and Canada Research Chair in machine learning for health.

Yixin Chen is a computer scientist, academic, and author. He is a professor of computer science and engineering at Washington University in St. Louis.

References

  1. 1 2 3 "Brendan J. Frey". Canadian Institute for Advanced Research. Archived from the original on 2015-11-20. Retrieved 2015-11-19.
  2. 1 2 3 "Levente Diosady and Brendan Frey named fellows of the Royal Society of Canada - U of T Engineering News". U of T Engineering News. 2015-09-08. Retrieved 2015-11-19.
  3. "Professor Brendan Frey John C. Polanyi Award". Ottawa: NSERC. 2016-06-28.
  4. Brendan Frey at the Mathematics Genealogy Project
  5. Brendan Frey's Academic Genealogy
  6. 1 2 Lohr, Steve (21 October 2018). "From Agriculture to Art — the A.I. Wave Sweeps In". The New York Times. Retrieved 2018-10-21.
  7. 1 2 3 "Donnelly Center Profile of Brendan Frey". Archived from the original on 2016-03-04. Retrieved 2015-11-21.
  8. "Meet Deep Genomics, a start-up bringing the power of deep learning to genomics". The Washington Post . Retrieved 2015-11-21.
  9. "New company plans to revolutionize genomic medicine with deep learning". 27 July 2015. Retrieved 2015-11-21.
  10. "Taking The Genome Further In Healthcare". 17 December 2015. Retrieved 2015-12-17.
  11. "SpaceX investor backs Toronto AI upstart's journey into the 'dark region' of genetic diseases" . Retrieved 2020-01-07.
  12. "Deep Genomics Scores 180m to Deliver AI Programmed RNA Therapies" . Retrieved 2021-07-28.
  13. "IEEE TIP Contributors". IEEE Transactions on Information Theory. 47 (2): 850–853. February 2001. doi:10.1109/TIT.2001.910596.