Established | 1874 |
---|---|
Affiliation | University of Cambridge |
Head of department | Mete Atature [1] |
Location | , United Kingdom 52°12′33″N00°05′33″E / 52.20917°N 0.09250°E |
Cavendish Professor of Physics | Vacant |
Website | www |
The Cavendish Laboratory is the Department of Physics at the University of Cambridge, and is part of the School of Physical Sciences. The laboratory was opened in 1874 on the New Museums Site as a laboratory for experimental physics and is named after the British chemist and physicist Henry Cavendish. The laboratory has had a huge influence on research in the disciplines of physics and biology.
The laboratory moved to its present site in West Cambridge in 1974.
As of 2019 [update] , 30 Cavendish researchers have won Nobel Prizes. [2] Notable discoveries to have occurred at the Cavendish Laboratory include the discovery of the electron, neutron, and structure of DNA.
The Cavendish Laboratory was initially located on the New Museums Site, Free School Lane, in the centre of Cambridge. It is named after British chemist and physicist Henry Cavendish [3] [4] for contributions to science [5] and his relative William Cavendish, 7th Duke of Devonshire, who served as chancellor of the university and donated funds for the construction of the laboratory. [6]
Professor James Clerk Maxwell, the developer of electromagnetic theory, was a founder of the laboratory and the first Cavendish Professor of Physics. [7] The Duke of Devonshire had given to Maxwell, as head of the laboratory, the manuscripts of Henry Cavendish's unpublished Electrical Works. The editing and publishing of these was Maxwell's main scientific work while he was at the laboratory. Cavendish's work aroused Maxwell's intense admiration and he decided to call the Laboratory (formerly known as the Devonshire Laboratory) the Cavendish Laboratory and thus to commemorate both the Duke and Henry Cavendish. [8] [9]
Several important early physics discoveries were made here, including the discovery of the electron by J.J. Thomson (1897) the Townsend discharge by John Sealy Townsend, and the development of the cloud chamber by C.T.R. Wilson.
Ernest Rutherford became Director of the Cavendish Laboratory in 1919. Under his leadership the neutron was discovered by James Chadwick in 1932, and in the same year the first experiment to split the nucleus in a fully controlled manner was performed by students working under his direction; John Cockcroft and Ernest Walton.
Physical Chemistry (originally the department of Colloid Science led by Eric Rideal) had left the old Cavendish site, subsequently locating as the Department of Physical Chemistry (under RG Norrish) in the then new chemistry building with the Department of Chemistry (led by Lord Todd) in Lensfield Road: both chemistry departments merged in the 1980s.
In World War II the laboratory carried out research for the MAUD Committee, part of the British Tube Alloys project of research into the atomic bomb. Researchers included Nicholas Kemmer, Alan Nunn May, Anthony French, Samuel Curran and the French scientists including Lew Kowarski and Hans von Halban. Several transferred to Canada in 1943; the Montreal Laboratory and some later to the Chalk River Laboratories. The production of plutonium and neptunium by bombarding uranium-238 with neutrons was predicted in 1940 by two teams working independently: Egon Bretscher and Norman Feather at the Cavendish and Edwin M. McMillan and Philip Abelson at Berkeley Radiation Laboratory at the University of California, Berkeley.
The Cavendish Laboratory has had an important influence on biology, mainly through the application of X-ray crystallography to the study of structures of biological molecules. Francis Crick already worked in the Medical Research Council Unit, headed by Max Perutz [10] [11] and housed in the Cavendish Laboratory, when James Watson came from the United States and they made a breakthrough in discovering the structure of DNA. For their work while in the Cavendish Laboratory, they were jointly awarded the Nobel Prize in Physiology or Medicine in 1962, together with Maurice Wilkins of King's College London, himself a graduate of St. John's College, Cambridge.
The discovery was made on 28 February 1953; the first Watson/Crick paper appeared in Nature on 25 April 1953. Sir Lawrence Bragg, the director of the Cavendish Laboratory, where Watson and Crick worked, gave a talk at Guy's Hospital Medical School in London on Thursday 14 May 1953 which resulted in an article by Ritchie Calder in the News Chronicle of London, on Friday 15 May 1953, entitled "Why You Are You. Nearer Secret of Life." The news reached readers of The New York Times the next day; Victor K. McElheny, in researching his biography, Watson and DNA: Making a Scientific Revolution, found a clipping of a six-paragraph New York Times article written from London and dated 16 May 1953 with the headline "Form of `Life Unit' in Cell Is Scanned." The article ran in an early edition and was then pulled to make space for news deemed more important. (The New York Times subsequently ran a longer article on 12 June 1953). The Cambridge University undergraduate newspaper Varsity also ran its own short article on the discovery on Saturday 30 May 1953. Bragg's original announcement of the discovery at a Solvay Conference on proteins in Belgium on 8 April 1953 went unreported by the British press.
Sydney Brenner, Jack Dunitz, Dorothy Hodgkin, Leslie Orgel, and Beryl M. Oughton, were some of the first people in April 1953 to see the model of the structure of DNA, constructed by Crick and Watson; at the time they were working at the University of Oxford's Chemistry Department. All were impressed by the new DNA model, especially Brenner who subsequently worked with Crick at Cambridge in the Cavendish Laboratory and the new Laboratory of Molecular Biology. According to the late Dr. Beryl Oughton, later Rimmer, they all travelled together in two cars once Dorothy Hodgkin announced to them that they were off to Cambridge to see the model of the structure of DNA. [12] Orgel also later worked with Crick at the Salk Institute for Biological Studies.
Due to overcrowding in the old buildings, it moved to its present site in West Cambridge in the early 1970s. [13] It is due to move again to a third site currently under construction in West Cambridge. [14]
The Cavendish Professors were the heads of the department until the tenure of Sir Brian Pippard, during which period the roles separated.
† Jacksonian Professors of Natural Philosophy
Areas in which the Laboratory has been influential include:-
As of 2023 [update] the laboratory is headed by Mete Atature. [1] The Cavendish Professor of Physics is Sir Richard Friend. [22]
As of 2015 [update] senior academic staff (professors or readers) include: [34]
The Cavendish is home to a number of emeritus scientists, pursuing their research interests in the laboratory after their formal retirement. [34]
Besides the Nobel Laureates, the Cavendish alumni include:
Francis Harry Compton Crick was an English molecular biologist, biophysicist, and neuroscientist. He, James Watson, Rosalind Franklin, and Maurice Wilkins played crucial roles in deciphering the helical structure of the DNA molecule.
Max Ferdinand Perutz was an Austrian-born British molecular biologist, who shared the 1962 Nobel Prize for Chemistry with John Kendrew, for their studies of the structures of haemoglobin and myoglobin. He went on to win the Royal Medal of the Royal Society in 1971 and the Copley Medal in 1979. At Cambridge he founded and chaired (1962–79) The MRC Laboratory of Molecular Biology (LMB), fourteen of whose scientists have won Nobel Prizes.
Sir Joseph John Thomson was an English physicist and Nobel Laureate in Physics who is credited with the discovery of the electron, the first subatomic particle to be found.
Maurice Hugh Frederick Wilkins was a New Zealand-born British biophysicist and Nobel laureate whose research spanned multiple areas of physics and biophysics, contributing to the scientific understanding of phosphorescence, isotope separation, optical microscopy, and X-ray diffraction. He is known for his work at King's College London on the structure of DNA.
Sir William Lawrence Bragg was an Australian-born British physicist and X-ray crystallographer, discoverer (1912) of Bragg's law of X-ray diffraction, which is basic for the determination of crystal structure. He was joint recipient of the Nobel Prize in Physics in 1915, "For their services in the analysis of crystal structure by means of X-rays"; an important step in the development of X-ray crystallography.
Sir Owen Willans Richardson, FRS was a British physicist who won the Nobel Prize in Physics in 1928 for his work on thermionic emission, which led to Richardson's law.
Charles Thomson Rees Wilson was a Scottish physicist and meteorologist who received the Nobel Prize in Physics in 1927 for his invention of the cloud chamber.
The Cavendish Professorship is one of the senior faculty positions in physics at the University of Cambridge. It was founded on 9 February 1871 alongside the famous Cavendish Laboratory, which was completed three years later. William Cavendish, 7th Duke of Devonshire endowed both the professorship and laboratory in honour of his relative, chemist and physicist Henry Cavendish.
Malcolm Sim Longair is a British physicist. From 1991 to 2008 he was the Jacksonian Professor of Natural Philosophy in the Cavendish Laboratory at the University of Cambridge. Since 2016 he has been Editor-in-Chief of the Biographical Memoirs of Fellows of the Royal Society.
Hugh Esmor Huxley was a British molecular biologist who made important discoveries in the physiology of muscle. He was a graduate in physics from Christ's College, Cambridge. However, his education was interrupted for five years by the Second World War, during which he served in the Royal Air Force. His contribution to development of radar earned him an MBE.
Sir John Sealy Edward Townsend was an Irish-British mathematical physicist who conducted various studies concerning the electrical conduction of gases and directly measured the electrical charge. He was a Wykeham Professor of physics at Oxford University.
David Shoenberg was a British physicist who worked in condensed matter physics. Shoenberg is known for having developed experimental and theoretical principles to study the De Haas–Van Alphen effect to characterize the electrical conduction of metals.
The Medical Research Council (MRC) Laboratory of Molecular Biology (LMB) is a research institute in Cambridge, England, involved in the revolution in molecular biology which occurred in the 1950–60s. Since then it has remained a major medical research laboratory at the forefront of scientific discovery, dedicated to improving the understanding of key biological processes at atomic, molecular and cellular levels using multidisciplinary methods, with a focus on using this knowledge to address key issues in human health.
Sir Alfred Brian Pippard, FRS, was a British physicist. He was Cavendish Professor of Physics from 1971 until 1982 and an Honorary Fellow of Clare Hall, Cambridge, of which he was the first President.
Sir Charles William Oatley was Professor of Electrical Engineering, University of Cambridge, 1960–1971, and developer of one of the first commercial scanning electron microscopes. He was also a founder member of the Royal Academy of Engineering.
The Department of Physics and Astronomy at the University of Manchester is one of the largest and most active physics departments in the UK, taking around 250 new undergraduates and 50 postgraduates each year, and employing more than 80 members of academic staff and over 100 research fellows and associates. The department is based on two sites: the Schuster Laboratory on Brunswick Street and the Jodrell Bank Centre for Astrophysics in Cheshire, international headquarters of the Square Kilometre Array (SKA).
Harold Albert Wilson FRS was an English physicist.
Allan Roy Mackintosh, FRS was a prominent Danish physicist and a leading authority on magnetism and neutron scattering, especially in the rare-earth metals.
David W. Green was a crystallographer at the Medical Research Council Unit for the Study of the Molecular Structure of Biological Systems, Cavendish Laboratory, University of Cambridge.
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