citrullinase | |||||||||
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Identifiers | |||||||||
EC no. | 3.5.1.20 | ||||||||
CAS no. | 59088-17-4 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a citrullinase (EC 3.5.1.20) is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are L-citrulline and H2O, whereas its 3 products are L-ornithine, CO2, and NH3.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is L-citrulline N5-carbamoyldihydrolase. Other names in common use include citrulline ureidase, citrulline hydrolase, and L-citrulline 5-N-carbamoyldihydrolase.
The urea cycle (also known as the ornithine cycle) is a cycle of biochemical reactions that produces urea (NH2)2CO from ammonia (NH3). Animals that use this cycle, mainly amphibians and mammals, are called ureotelic.
The enzyme fusarinine-C ornithinesterase (EC 3.1.1.48) catalyzes the reaction
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