Clear aligners

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Clear aligners
Invisalign aligner.jpg
An Invisalign aligner

Clear aligners are orthodontic devices that are a transparent, plastic form of dental braces used to adjust teeth. [1]

Contents

Clear aligners have undergone changes, making assessment of effectiveness difficult. [2] A 2014 systematic review concluded that published studies were of insufficient quality to determine effectiveness. [3] Experience suggests they are effective for moderate crowding of the front teeth, but less effective than conventional braces for several other issues [n 1] and are not recommended for children.[ further explanation needed ] In particular they are indicated for "mild to moderate crowding (1–6 mm) and mild to moderate spacing (1–6 mm)", in cases where there are no discrepancies of the jawbone. They are also indicated for patients who have experienced a relapse after fixed orthodontic treatment. [5]

Clear-aligner treatment involves an orthodontist or dentist, or with home-based systems, the person themselves, taking a mold of the patient's teeth, which is used to create a digital tooth scan. The computerized model suggests stages between the current and desired teeth positions, and aligners are created for each stage. Each aligner is worn for 22 hours a day for one or two weeks. [6] These slowly move the teeth into the position agreed between the orthodontist or dentist and the patient. The average treatment time is 13.5 months. [7] Despite patent infringement litigation, no manufacturer has obtained an injunction against another manufacturer.

Uses

A 2014 systematic review concluded that there is insufficient evidence to determine the effectiveness of these clear aligners. [3] Opinion is that they are likely useful for moderate front-teeth crowding. In those with teeth that are too far forward or backward, or rotated in the socket, the aligners are likely not as effective as conventional braces. More cases of relapse of the anterior teeth have been found with clear aligners compared with conventional braces. [4] A 2013 Cochrane review found no high-quality evidence with respect to the management of the recurrence of lower-front-teeth misalignment following treatment. [8]

Clear aligners are more noticeable than lingual braces, but they can be removed, which makes cleaning of the teeth easier, and they are faster for the dentist to apply. [4]

Application

3D representation of a person's teeth in the Invisalign software Invisalign software user interface.png
3D representation of a person's teeth in the Invisalign software

Treatment begins with taking x-ray and photographs for diagnostic purposes, followed by capturing the patient's bite, teeth, and gums via a bite registration and polyvinyl siloxane impressions or an intra-oral digital scanner. The latter method has greatly increased in popularity in recent years as digital scanning technology has improved. The dentist/orthodontist completes a written evaluation that includes diagnosis and treatment plan. [9] [10] [11] [12] Dental impressions are scanned in order to create a digital 3D representation of the teeth. [10] [11] Technicians move the teeth to the desired location with the program Treat, which creates the stages between the current and desired teeth positions. [11] [12] [13] Anywhere from six to eighty aligners may be needed during the first set of aligners. Each aligner moves teeth .25 to .33 millimeters. [6] [9] Additional and subsequent rounds of aligners, known as "Refinements", may be necessary to achieve desired tooth positions as clear aligners do not always achieve full movement in the first round. [14]

A computer graphic representation of the projected teeth movements, created in the software program ClinCheck, is provided to the doctor and patient for approval or modification before aligners are manufactured. [9] [11] [13] The aligners are modeled using CAD/CAM (computer-aided-design and computer-aided-manufacturing) software and manufactured using a rapid prototyping technique called stereolithography. [10] [11] The molds for the aligners are built in layers using a photo-sensitive liquid resin that cures into a hard plastic when exposed to a laser. [10] The aligners are made from an elastic thermoplastic material that applies pressure to the teeth to move into the aligner's position. [13] [15] [16] Patients that need a tooth rotated or pulled down may have a small, tooth-colored [17] composite attachment bonded onto certain teeth. [13] Since the form-fitted plastic used in clear aligners is not as rigid as the metal used in traditional braces, sometimes the flexibility in the materials need to be compensated in the areas that require movement. Alternatively, attachments may be used to facilitate movement by changing the shape of the tooth. [18] More attachments can make the aligners less aesthetically pleasing. [11] Interproximal reduction (IPR, also called reproximation or, colloquially, filing or drilling) is sometimes used at the contacts between teeth to allow for a better fit. [19] [20]

Each aligner is intended to be worn an optimal 22 hours a day for one to two weeks. [6] On average the treatment process takes 13.5 months, [7] although treatment time varies based on the complexity of the planned teeth movements. [6] The aligner is removed for brushing, flossing and eating. As clear aligners are made from plastic, they can be warped by hot liquids. While undergoing treatment one should limit their intake of hot liquids to protect the shape of the aligners and stop them from becoming stained. [21] Once the treatment period has concluded, the patient is advised to continue wearing a retainer at night for the foreseeable future. [22]

When the Invisalign system was first developed, many of the aligner manufacturing processes were carried out by hand, and computer technicians had to modify each tooth in the computerized model individually. [10]

Brands

Invisalign

Woman wearing an Invisalign clear aligner Woman wearing Invisalign, 2008 (cropped).jpg
Woman wearing an Invisalign clear aligner

Invisalign is manufactured by Align Technology, an American multinational medical-device company. The company's clear align system has been used to treat more than 12.2 million patients. [2]

The company was founded in 1997 by Zia Chishti. Chishti conceived of the basic design of InvisAlign while an adult orthodontics patient. During his treatment with a retainer intended to complete his treatment, he posited that a series of such devices could effect a large final placement in a series of small movements. [9] [10] [23]

Sales began in the U.S. in 1999. [4] [11]

Orthodontists were resistant to adopting Invisalign at first, in particular because the founders had no orthodontic credentials or expertise, but the product became popular among consumers. [9] As of 2014, 80,000 dentists had been trained how to use it. [4]

Orthoclear

Zia Chishti was ousted from Align Technology in 2002. In 2005 he developed Orthoclear, a similar product, which resulted in several legal disputes involving allegations of patent infringement, false advertising, defamation and trademark infringement. The case was settled in 2006. [24] [25] [26] Align paid OrthoClear $20 million and OrthoClear agreed to end its operations. [25]

ClearCorrect

ClearCorrect, LLC, based in Round Rock, Texas, was established in 2006. The company distributes its product throughout the United States, and in 2011 was named the fastest-growing health company in America by Inc. magazine. [27] [28] It has been reported that in 2017 its clear align system had been used to treat about 80,000 patients. [2]

ClearCorrect was founded in Houston, Texas, by Willis Pumphrey, Jr., a dentist. [29] [30] In 2001, Pumphrey started using Invisalign. [24] [31] He decided to switch to OrthoClear, because of the way OrthoClear manufactured its aligners and because of its reduced lab fees. [32] When manufacture of Orthoclear ceased, Pumphrey had 400 patients in treatment. With no other options available, he started his own company to complete his patients' clear aligner treatment. [33]

Direct-to-consumer brands

SmileDirectClub

SmileDirectClub, based in Nashville, Tennessee, was launched in 2014 as an alternative to in-office clear aligners. The company offered direct-to-consumer clear aligner service which can be used from home, without having to see a dentist. This allowed them to price aligners at half of the other competitors. The company faced criticism from the orthodontic community because of no involvement of a physical dentist. [34] Similar startups have also launched in different parts of the world. In September 2023, SmileDirectClub filed for bankruptcy, before shutting down completely in December 2023, leaving thousands of customers without any support. [35]

Smile White

Smile White is a UK-based company that offers clear aligners. In June 2023, the brand was acquired by twin dentists Hussein and Hassan Dalghous, known on TikTok as TwinDentists. [36]

Direct to consumer clear aligner services

Following SmileDirectClub, multiple companies provide aligner treatment to patients by mailing their aligners and monitoring the treatment through a digital platform. The American Association of Orthodontists, the largest society representing orthodontists in the United States and abroad, released consumer alert explaining potential risks associated with such services. [37]

Society and culture

Lawsuits

The litigious history in the clear aligner market prompted ClearCorrect to be proactive in addressing patent issues between itself and Align Technology. Align had previously filed a complaint with the U.S. International Trade Commission against OrthoClear Inc. In the end an agreement was made between Align and OrthoClear in which Align paid OrthoClear $20 million for its intellectual property and OrthoClear agreed to stop accepting cases in the United States. [24]

In 2009, Align Technology began to require that doctors prescribing Invisalign complete at least ten cases per year and ten hours of training in order to maintain their Invisalign provider status. In January 2010, 20,000 doctors had their certification suspended for not meeting the requirements, but a class action lawsuit regarding providers that paid for training under the original rules resulted in some certifications being re-instated. [38]

In February 2009, ClearCorrect filed a declaratory judgment against Align Technology. ClearCorrect claimed that some of Align's patents were invalid, and thus ClearCorrect's product did not infringe on Align's patents. [33] ClearCorrect voluntarily dismissed the suit in April 2009, after Align stated to the court that it had no intention of suing ClearCorrect for patent infringement. [33] [39]

On February 28, 2011, Align Technology filed two lawsuits against ClearCorrect. Align alleged that under California's Unfair Practices Act, that ClearCorrect sold products for a price below the average production cost, with the purpose of "destroying competition in the market for clear aligner systems". Align also claimed that ClearCorrect infringed eight of Align's patents. [40]

On May 12, 2011, ClearCorrect filed a countersuit against Align Technology, denying allegations that it is infringing on Align patents. In the countersuit, ClearCorrect alleged that Align's allegations are invalid and accused Align of patent misuse and double patenting. The countersuit cited much of the evidence raised in Align's previous patent case against Ormco, which resulted in a federal court ruling that 11 of Align's patent claims were invalid. [41] [42]

In September 2023, SmileDirectClub filed for bankruptcy. While SmileDirectClub initially sought Chapter 11 bankruptcy protection to restructure its finances, it was unable to secure the necessary funding and ultimately shut down its operations in December 2023. [43]

October 2024: Dentsply Sirona voluntarily suspended the sale and marketing of its Byte clear aligners and impression kits as it conducts a review of regulatory requirements. [44]

Costs

The cost of clear aligners is typically lower than their all-metal counterparts because of the materials and technology used. Prices are rarely impacted by factors such as the duration of the treatment and the extent of the issues requiring correction, as much as specific details of the treatment plan, time/age of treatment, location, the experience of the orthodontist. In countries such as Australia, Canada, United States and United Kingdom prices are fairly similar across providers at circa $2,000/£1,500. [45] [46] [47] [48] [49]

Notes

  1. Daniel A. Kuncio (The New York State Dental Journal), 2014: "Invisalign has been proven to resolve moderate anterior tooth crowding predictably, but treatment outcome studies have highlighted Invisalign's weaknesses compared to conventional braces in treating anterior-posterior discrepancies, large rotational movements and the extrusion of teeth. More post-treatment relapse of anterior dental alignment has also been found in Invisalign cases." [4]

Related Research Articles

<span class="mw-page-title-main">Orthodontics</span> Correctional branch of dentistry

Orthodontics is a dentistry specialty that addresses the diagnosis, prevention, management, and correction of mal-positioned teeth and jaws, as well as misaligned bite patterns. It may also address the modification of facial growth, known as dentofacial orthopedics.

<span class="mw-page-title-main">Retainer (orthodontics)</span> Device to hold teeth in position

Orthodontic retainers are custom-made devices, usually made of wires or clear plastic, that hold teeth in position after surgery or any method of realigning teeth. Once a phase of orthodontic treatment has been completed to straighten teeth, there remains a lifelong risk of relapse due to a number of factors: recoil of periodontal fibres, pressure from surrounding soft tissues, the occlusion and patient’s continued growth and development. By using retainers to hold the teeth in their new position for a length of time, the surrounding periodontal fibres adapt to changes in the bone which can help minimize any changes to the final tooth position after the completion of orthodontic treatment. Retainers may also be used to treat overjets.

<span class="mw-page-title-main">Dental braces</span> Form of orthodontics

Dental braces are devices used in orthodontics that align and straighten teeth and help position them with regard to a person's bite, while also aiming to improve dental health. They are often used to correct underbites, as well as malocclusions, overbites, open bites, gaps, deep bites, cross bites, crooked teeth, and various other flaws of the teeth and jaw. Braces can be either cosmetic or structural. Dental braces are often used in conjunction with other orthodontic appliances to help widen the palate or jaws and to otherwise assist in shaping the teeth and jaws.

Cosmetic dentistry is generally used to refer to any dental work that improves the appearance of teeth, gums and/or bite. It primarily focuses on improvement in dental aesthetics in color, position, shape, size, alignment and overall smile appearance. Many dentists refer to themselves as "cosmetic dentists" regardless of their specific education, specialty, training, and experience in this field. This has been considered unethical with a predominant objective of marketing to patients. The American Dental Association does not recognize cosmetic dentistry as a formal specialty area of dentistry. However, there are still dentists that promote themselves as cosmetic dentists.

<span class="mw-page-title-main">Dental technician</span> Technician working on dental appliances

A dental technician is a member of the dental team who, upon prescription from a dental clinician, constructs custom-made restorative and dental appliances.

<span class="mw-page-title-main">Malocclusion</span> Misalignment between upper and lower teeth as the jaws close

In orthodontics, a malocclusion is a misalignment or incorrect relation between the teeth of the upper and lower dental arches when they approach each other as the jaws close. The English-language term dates from 1864; Edward Angle (1855–1930), the "father of modern orthodontics", popularised it. The word derives from mal- 'incorrect' and occlusion 'the manner in which opposing teeth meet'.

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<span class="mw-page-title-main">Edward Angle</span> American dentist (1855–1930)

Edward Hartley Angle was an American dentist, widely regarded as "the father of American orthodontics". He was trained as a dentist, but made orthodontics his speciality and dedicated his life to standardizing the teaching and practice of orthodontics. He founded the Angle School of Orthodontia in 1899 in St. Louis and schools in other regions of the United States. As the originator of the profession, Angle founded three orthodontic schools between 1905 and 1928 in St. Louis, Missouri, New London, Connecticut and Pasadena, California. These exclusive institutions provided the opportunity for several pioneering American orthodontists to receive their training.

<span class="mw-page-title-main">Crossbite</span> Left-right misalignment of upper and lower teeth

In dentistry, crossbite is a form of malocclusion where a tooth has a more buccal or lingual position than its corresponding antagonist tooth in the upper or lower dental arch. In other words, crossbite is a lateral misalignment of the dental arches.

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<span class="mw-page-title-main">All Smiles Dental Centers</span>

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Dustin Burleson is an American orthodontist and consultant.

Elastics are rubber bands frequently used in the field of orthodontics to correct different types of malocclusions. The elastic wear is prescribed by an orthodontist or a dentist in an orthodontic treatment. The longevity of the elastic wear may vary from two weeks to several months. The elastic wear can be worn from 12 to 23 hours a day, either during the night or throughout the day depending on the requirements for each malocclusion. The many different types of elastics may produce different forces on teeth. Therefore, using elastics with specific forces is critical in achieving a good orthodontic occlusion.

<span class="mw-page-title-main">Align Technology</span> American company that produces orthodontics devices

Align Technology, Inc. is an American manufacturer of 3D digital scanners and Invisalign clear aligners used in orthodontics and restorative workflow. It was founded in 1997 and is headquartered in Tempe, Arizona. The company manufactures the aligners in Juarez, Mexico, and its scanners in Israel and China. The company is best known for its Invisalign system, which is a clear aligner treatment used to straighten teeth.

<span class="mw-page-title-main">SmileDirectClub</span> Teledentistry company (2014–2023)

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References

  1. "Traditional Braces vs Clear Aligners like Invisalign". Orthodontics Australia. 2020-09-01. Retrieved 2021-02-06.
  2. 1 2 3 Weir, T. (2017). "Clear aligners in orthodontic treatment". Australian Dental Journal. 62: 58–62. doi: 10.1111/adj.12480 . PMID   28297094.
  3. 1 2 Rossini, G.; Parrini, S.; Castroflorio, T.; Deregibus, A.; Debernardi, CL. (Nov 2014). "Efficacy of clear aligners in controlling orthodontic tooth movement: A systematic review". Angle Orthod. 85 (5): 881–9. doi: 10.2319/061614-436.1 . PMC   8610387 . PMID   25412265. S2CID   10787375. The quality level of the studies was not sufficient to draw any evidence-based conclusions.
  4. 1 2 3 4 5 Kuncio, Daniel A. (March 2014). "Invisalign: current guidelines for effective treatment". The New York State Dental Journal. 80 (2): 11–4. PMID   24851387.
  5. John D. Da Silva, Oxford American Handbook of Clinical Dentistry, New York: Oxford University Press, p.  162.
  6. 1 2 3 4 Malik, Ovals; McMullin, Allbhe; Waring, David (April 2013). "Invisible Orthodontics Part 1: Invisalign". Dental Update. 40 (3): 203–4, 207–10, 213–5. doi:10.12968/denu.2013.40.3.203. PMID   23767109.
  7. 1 2 Fogel, Joshua; Janani, Raymond (2010). "Intentions and behaviors to obtain Invisalign". Journal of Medical Marketing. 10 (2): 135–145. doi:10.1057/jmm.2009.50. ISSN   1745-7904.
  8. Yu, Y; Sun, J; Lai, W; Wu, T; Koshy, S; Shi, Z (6 September 2013). "Interventions for managing relapse of the lower front teeth after orthodontic treatment". The Cochrane Database of Systematic Reviews. 9 (9): CD008734. doi:10.1002/14651858.CD008734.pub2. PMC   10793711 . PMID   24014170.
  9. 1 2 3 4 5 Basavaraj Subhashchandra Phulari (30 June 2013). History of Orthodontics. JP Medical Ltd. p. 1. ISBN   978-93-5090-471-8.
  10. 1 2 3 4 5 6 Tuncay, Orhan (2006). The Invisalign System. Quintessence Publishing Co, Ltd. ISBN   978-1850971276.
  11. 1 2 3 4 5 6 7 Rakosi, Thomas; Graber, Thomas M. (2010). Orthodontic and Dentofacial Orthopedic Treatment. Thieme. ISBN   978-3-13-127761-9.
  12. 1 2 Bishop, A.; Womack, R.; Derakhshan, M. (September–October 2002), "An esthetic and removable orthodontic treatment option for patients: Invisalign", The Dental Assistant, 71 (5): 14–7, PMID   12387123
  13. 1 2 3 4 Melsen, Birte (3 February 2012). Adult Orthodontics. John Wiley & Sons. pp. 353–. ISBN   978-1-4443-5574-1.
  14. Haouili, Nada; Kravitz, Neal D.; Vaid, Nikhilesh R.; Ferguson, Donald J.; Makki, Laith (2020-09-01). "Has Invisalign improved? A prospective follow-up study on the efficacy of tooth movement with Invisalign". American Journal of Orthodontics and Dentofacial Orthopedics. 158 (3): 420–425. doi: 10.1016/j.ajodo.2019.12.015 . ISSN   0889-5406. PMID   32620479.
  15. Cowley, Daniel (August 1, 2012), Effect of Gingival Margin Design on Retention of Thermoformed Orthodontic Aligners, University of Nevada, retrieved March 11, 2014
  16. Alexander, Justin (2012), Effect of Reducing the Incremental Distance of Tooth Movement per Aligner while Maintaining Overall Rate of Movement on Self-Reported Discomfort in Invisalign Patients (PDF), Saint Louis University, archived from the original (PDF) on March 29, 2014, retrieved March 11, 2014
  17. Joffe, L. (2003). "Invisalign(R): early experiences". Journal of Orthodontics. 30 (4): 348–352. doi:10.1093/ortho/30.4.348. ISSN   1465-3133. PMID   14634176.
  18. "The role of attachments in clear aligner treatment". orthodonticsaustralia.org.au. November 2, 2018.
  19. Humber, PV (2008), "A Snapshot of Invisalign", Aesthetic Dentistry Today, 2 (1): 85–88, archived from the original on 2012-03-16, retrieved 2011-01-28
  20. Boyd, RL (August 2008), "Esthetic orthodontic treatment using the invisalign appliance for moderate to complex malocclusions", Journal of Dental Education , 72 (8): 948–67, doi:10.1002/j.0022-0337.2008.72.8.tb04570.x, PMID   18676803, archived from the original on September 30, 2019, retrieved January 28, 2011
  21. "6 Things you didn't know about clear aligners". orthodonticsaustralia.org.au. October 18, 2018.
  22. Howley, Elaine K. (25 Jan 2022). "How Much Do Invisible Braces Cost?". U.S. News & World Report. Retrieved 8 Feb 2022.
  23. Coughlan, Anne; Hennessy, Julie, Invisalign: Orthodontics Unwired, Kellogg School of Management}
  24. 1 2 3 "OrthoClear, Align end lengthy legal fight". Silicon Valley Business Journal. September 28, 2006. Retrieved January 9, 2013.
  25. 1 2 Benesh, Peter (March 19, 2007). "No More Mouthfuls of Metal". Investor's Business Daily. Retrieved January 9, 2013.
  26. "Align Technology and OrthoClear end Litigation" (PDF). Ortho Tribune. October 16, 2006. Archived from the original (PDF) on September 23, 2015. Retrieved January 7, 2013.
  27. "Inc. Company Profile Rank". 2018-08-15.
  28. "ClearCorrect honored by Inc. magazine". DrBicuspid.com. August 30, 2011.
  29. Del Williams (Jan 21, 2021). "A Clear Choice in the Dental Aligner Market: Doctors welcome options".
  30. "Dental Cosmetic Center of Houston". Archived from the original on April 25, 2012.
  31. Lynn S. (17 July 2019). "Invisible braces". ArchWired.com.
  32. Necessity Knows The Law – The Next Stage Bootstrapper, Texas CEO magazine, 10 January 2011, archived from the original on 2 November 2019, retrieved 2 September 2015
  33. 1 2 3 Casey Wooten (August 23, 2009). "Competing at the cutting edge". The Business Journals.
  34. "Getting Your Teeth Straightened at a Strip Mall? Doctors Have a Warning". Bloomberg. September 20, 2018.
  35. "Smile Direct Club dentistry aligners firm shuts down". BBC. 2023-12-10. Retrieved 2023-12-18.
  36. "Leeds twin millionaires at helm of dentistry empire whose clients include Leeds United players make eight-figure business purchase". Yorkshire Post. 2023.
  37. "Consumer Alert: Questions to Consider When Researching Direct-To-Consumer Orthodontic Companies". American Association of Orthodontists. Retrieved 2020-08-16.
  38. Rasmussen, March (March 2011), Invisalign Agrees to Settlement in Class Action Lawsuit, American Dental Association, retrieved March 25, 2014
  39. "ClearCorrect Voluntarily Dismisses Lawsuit Against Invisalign" (Press release). Reuters. April 9, 2009. Archived from the original on September 24, 2015.
  40. "Align Technology Files Lawsuits Against ClearCorrect". GlobeNewswire. February 2, 2011.
  41. "ClearCorrect denies patent infringement, countersues Align". DrBicuspid.com. May 12, 2011.
  42. "Align Technology Files Patent Infringement and False Advertising Lawsuit Against SmileCareClub, Sharper Image, and". CNN. October 22, 2015. Archived from the original on October 25, 2015.
  43. "SmileDirectClub Bites the Dust After Crooked Business Practices".
  44. "Byte sales suspended, FDA probes adverse events: 8 clear aligner updates to know".
  45. "Comparison of UK Clear Teeth Aligner Treatment Costs". aligners.co.uk. 19 June 2022.
  46. "An Expert's Guide to Clear Aligner Treatment" (PDF). orthodonticsaustralia.org.au.
  47. "Clear Braces Guide: Information on Types, Costs and More in the UK". dentaly.org. 10 September 2023.
  48. "Clear Braces Guide: Information on Types, Costs and More". dentaly.org. 14 September 2023.
  49. "What are Invisalign Costs in Canada?". olympiabenefits.com.

Further reading