Deslanoside

Last updated
Deslanoside
Deslanoside.svg
Clinical data
AHFS/Drugs.com International Drug Names
ATC code
Identifiers
  • (3β,5β,12β)-3-[(O-β-D-glucopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard 100.037.774 OOjs UI icon edit-ltr-progressive.svg
Chemical and physical data
Formula C47H74O19
Molar mass 943.090 g·mol−1
  • InChI=1S/C47H74O19/c1-20-41(64-36-16-30(50)42(21(2)60-36)65-37-17-31(51)43(22(3)61-37)66-44-40(56)39(55)38(54)32(18-48)63-44)29(49)15-35(59-20)62-25-8-10-45(4)24(13-25)6-7-27-28(45)14-33(52)46(5)26(9-11-47(27,46)57)23-12-34(53)58-19-23/h12,20-22,24-33,35-44,48-52,54-57H,6-11,13-19H2,1-5H3/t20-,21-,22-,24-,25+,26-,27-,28+,29+,30+,31+,32-,33-,35+,36+,37+,38-,39+,40-,41-,42-,43-,44+,45+,46+,47+/m1/s1 Yes check.svgY
  • Key:OBATZBGFDSVCJD-LALPQLPRSA-N Yes check.svgY
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Deslanoside (trade name Cedilanide in Brazil [1] ) is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat). It is found in the leaves of Digitalis lanata , the Woolly Foxglove. [2] [3]

References

  1. "Cedilanide". Drugs.com. Archived from the original on 2019-08-15. Retrieved 2018-01-23.
  2. Bakke OM, Aslaksen A, Lehmann V, Lien E (1981). "Pharmacokinetics and serum concentration--effect relationship of intravenous deslanoside". Journal of Cardiovascular Pharmacology. 3 (5): 1015–25. doi: 10.1097/00005344-198109000-00012 . PMID   6168847.
  3. Budavari S, ed. (1996). The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals (12th ed.). Merck. ISBN   0911910123.,2967