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Frank LoVecchio | |
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Citizenship | American |
Occupation(s) | Emergency medicine physician, medical toxicologist, academic, researcher, lecturer |
Academic background | |
Alma mater | State University of New York at Stony Brook (BA) New York Institute of Technology College of Osteopathic Medicine (DO) Harvard School of Public Health (MPH) |
Academic work | |
Institutions | College of Health Solutions Banner - University Medical Center Phoenix |
Frank LoVecchio is an American emergency medicine physician,medical toxicologist,academic and researcher. [1] He is the medical director of Clinical Research at College of Health Solutions,the Director of Good Samaritan Regional Poison Center,the Research Director of Maricopa Medical Center Emergency Medicine Program,and clinical professor at Arizona College of Osteopathic Medicine. He also serves as an attending physician at Valleywise Health,Phoenix Children's Hospital,and in the Department of Medical Toxicology at Banner University Medical Center. [2] [3] [4] [5]
LoVecchio has authored various scholarly publications and book chapters. [4] His research includes ketone levels in the lungs and blood,and pesticide exposures and scorpion stings in young children. He has served as primary or co-investigator on several National Institutes of Health grants. [1]
He is one of the founding members of the Center for Toxicology and Pharmacology Education and Research of the University of Arizona College of Medicine. [6] He is also associated with several professional organizations and societies,including American Board of Addiction Medicine,American College of Medical Toxicologists,American College of Emergency Physicians,Emergency Medicine Resident Association,Society of Academic Emergency Medicine,American Society of Forensic Examiners,and American Osteopathic Association. [7] He has been a keynote speaker for numerous conferences,and has contributed on various media outlets. [8] [9] [10]
LoVecchio studied at State University of New York at Stony Brook and received his bachelor's degree in General Science in 1988. He earned his Doctor of Osteopathic Medicine degree from New York College of Osteopathic Medicine in 1992 and a Master of Public Health from Harvard School of Public Health in 2002. [1] [2] He then completed his internship at St. Barnabas Hospital,affiliated with Cornell Medical College and New York College of Osteopathic Medicine in 1993,his residency at Mount Sinai School of Medicine Integrated Residency in Emergency Medicine, [11] Beth Israel Medical Center &City Hospital Center at Elmhurst in 1996,and his fellowship in Medical Toxicology at Good Samaritan Regional Medical Center in 1998. [12] He is also board certified in Addiction Medicine and Medical Forensics. [1] [4]
LoVecchio joined New York City Emergency Medical Service Academy as a lecturer in 1995. In 2007,he held an appointment as clinical professor at Arizona College of Osteopathic Medicine. [13] He also held administrative appointments in his career. In 1998,he was appointed by Good Samaritan Regional Poison Center as an Associate Medical Director. [11] He was associated with a program in Clinical Effectiveness at Harvard School of Public Health from 1999 till 2002,and with Federal Emergency Medical Assistance Program from 1998 till 2005. He served as Resident Research Director and then held appointment as a vice-chair of Department of Emergency Medicine at Maricopa Medical Center,University of Arizona College of Medicine 2009 to 2019. [1] He was named medical director of Clinical Research at College of Health Solutions and is one of the founders of the Translational Research Center at Arizona State University. [2]
LoVecchio's research mainly focuses on ketone levels in the lungs and blood,and pesticide exposures and scorpion stings in young children. He has advocated in the legal arena regarding medical toxicology,emergency medicine,addiction,product safety and public health issues, [14] [15] and has also worked as an on-air expert on topics including,public health,opioid crisis,and COVID-19. [16] [17] [18] He was featured in National Geographic’Drugs,Inc. Flesh-Eating Krokodil episode. [19]
He has received funding to study suicide prevention,respiratory diseases,CPR,sepsis,and MRSA infections.
In a February 2021 New York Times documentary following Valleywise healthcare workers, LoVecchio gave positive remarks on the expected future COVID-19 situation in Arizona. [20] In September of that year, he was part of a study that conducted a test-negative case-control investigation regarding the effectiveness of Moderna COVID-19 vaccine among U.S. health care personnel. [21]
In 2014, LoVecchio conducted a multicenter trial in the tertiary care setting, and found out that protocol-based resuscitation of patients in whom septic shock was diagnosed in the emergency department did not improve outcomes. [22] In his paper published in 2010, he investigated the survival rate of patients with out-of-hospital cardiac arrest using compression-only CPR (COCPR) compared with conventional CPR. Results of his study showed that layperson compression-only CPR was associated with increased survival in comparison to conventional CPR and no bystander CPR in this setting with public endorsement of chest compression–only CPR. [23]
LoVecchio also investigated the influence of the infecting pathogen on the hospital length of stay (LOS) for acute bronchiolitis. He determined that RSV was more frequently detected virus in children hospitalized with bronchiolitis, as compared to HRV; which was detected in one-quarter of the children. [24] Furthermore, he studied procalcitonin-guided use of antibiotics in context of lower respiratory tract infection. [25]
In 1997, The dogma of avoiding analgesics in patients with acute abdominal pain [26] was challenged, and in one of the first studies addressing this issue, LoVecchio and his colleagues, concluded that physical examination does change after the administration of analgesics in patients with acute abdominal pain. [27] He also conducted a study to determine the impact of ED-initiated intervention in terms of subsequent suicidal behavior. [28]
LoVecchio published a paper in 2008 focused on how poison control centers decrease emergency healthcare utilization costs, and determined that the home management by Banner Poison Control Center provided large monetary savings to residents in comparison to dollars received in state support. [29] He also focused his study on the centruroides sculpturatus and regarded it as the only scorpion native to the United States whose venom produces life‐threatening illness. He studied the distribution of the severity grades following scorpion envenomations, the time to deterioration, the onset of clinical signs and symptoms, and side effects regarding the antivenom treatment in children of particular age. [30]
LoVecchio reviewed poison center data charts from January 2007 through December 2009, and discussed the outcomes of unintentional beta-blocker or calcium channel blocker overdoses among patients. [31] Furthermore, he conducted a 5-year retrospective poison control center review and explored the outcomes regarding chlorine exposure in 598 patients. [32]
Emergency medicine is the medical speciality concerned with the care of illnesses or injuries requiring immediate medical attention. Emergency physicians specialise in providing care for unscheduled and undifferentiated patients of all ages. As first-line providers, in coordination with emergency medical services, they are primarily responsible for initiating resuscitation and stabilization and performing the initial investigations and interventions necessary to diagnose and treat illnesses or injuries in the acute phase. Emergency physicians generally practise in hospital emergency departments, pre-hospital settings via emergency medical services, and intensive care units. Still, they may also work in primary care settings such as urgent care clinics.
A do-not-resuscitate order (DNR), also known as Do Not Attempt Resuscitation (DNAR), Do Not Attempt Cardiopulmonary Resuscitation (DNACPR), no code or allow natural death, is a medical order, written or oral depending on country, indicating that a person should not receive cardiopulmonary resuscitation (CPR) if that person's heart stops beating. Sometimes these decisions and the relevant documents also encompass decisions around other critical or life-prolonging medical interventions. The legal status and processes surrounding DNR orders vary from country to country. Most commonly, the order is placed by a physician based on a combination of medical judgement and patient involvement.
Internal medicine or general internal medicine is the medical specialty dealing with the prevention, diagnosis, and treatment of internal diseases. Doctors specializing in internal medicine are called internists, or physicians in Commonwealth nations. Internists are medical specialists that are skilled in the management of patients who have undifferentiated or multi-system disease processes. Internists care for hospitalized (inpatient) and ambulatory (outpatient) patients and may play a major role in teaching and research. Internists are qualified physicians with postgraduate training in internal medicine and should not be confused with "interns", a term for doctors in their first year of residency training.
The United States National Library of Medicine (NLM), operated by the United States federal government, is the world's largest medical library.
Carbon monoxide poisoning typically occurs from breathing in carbon monoxide (CO) at excessive levels. Symptoms are often described as "flu-like" and commonly include headache, dizziness, weakness, vomiting, chest pain, and confusion. Large exposures can result in loss of consciousness, arrhythmias, seizures, or death. The classically described "cherry red skin" rarely occurs. Long-term complications may include chronic fatigue, trouble with memory, and movement problems.
Chelation therapy is a medical procedure that involves the administration of chelating agents to remove heavy metals from the body. Chelation therapy has a long history of use in clinical toxicology and remains in use for some very specific medical treatments, although it is administered under very careful medical supervision due to various inherent risks, including the mobilization of mercury and other metals through the brain and other parts of the body by the use of weak chelating agents that unbind with metals before elimination, exacerbating existing damage. To avoid mobilization, some practitioners of chelation use strong chelators, such as selenium, taken at low doses over a long period of time.
The American College of Emergency Physicians (ACEP) is a professional organization of emergency medicine physicians in the United States. ACEP publishes the Annals of Emergency Medicine and the Journal of the American College of Emergency Physicians Open.
The United States Medical Licensing Examination (USMLE) is a three-step examination program for medical licensure in the United States sponsored by the Federation of State Medical Boards (FSMB) and the National Board of Medical Examiners (NBME). Physicians with a Doctor of Medicine (MD) degree are required to pass the USMLE for medical licensure. However, those with a Doctor of Osteopathic Medicine degree (DO) are required to take the COMLEX-USA (COMLEX) exams.
Nicotine poisoning describes the symptoms of the toxic effects of nicotine following ingestion, inhalation, or skin contact. Nicotine poisoning can potentially be deadly, though serious or fatal overdoses are rare. Historically, most cases of nicotine poisoning have been the result of use of nicotine as an insecticide. More recent cases of poisoning typically appear to be in the form of Green Tobacco Sickness, or due to unintended ingestion of tobacco or tobacco products or consumption of nicotine-containing plants.
A poison control center is a medical service that is able to provide immediate, free, and expert treatment advice and assistance over the telephone in case of exposure to poisonous or hazardous substances. Poison control centers answer questions about potential poisons in addition to providing treatment management advice about household products, medicines, pesticides, plants, bites and stings, food poisoning, and fumes. In the US, more than 72% of poison exposure cases are managed by phone, greatly reducing the need for costly emergency department and doctor visits.
A medical specialty is a branch of medical practice that is focused on a defined group of patients, diseases, skills, or philosophy. Examples include those branches of medicine that deal exclusively with children (paediatrics), cancer (oncology), laboratory medicine (pathology), or primary care. After completing medical school or other basic training, physicians or surgeons and other clinicians usually further their medical education in a specific specialty of medicine by completing a multiple-year residency to become a specialist.
Paracetamol poisoning, also known as acetaminophen poisoning, is caused by excessive use of the medication paracetamol (acetaminophen). Most people have few or non-specific symptoms in the first 24 hours following overdose. These symptoms include feeling tired, abdominal pain, or nausea. This is typically followed by absence of symptoms for a couple of days, after which yellowish skin, blood clotting problems, and confusion occurs as a result of liver failure. Additional complications may include kidney failure, pancreatitis, low blood sugar, and lactic acidosis. If death does not occur, people tend to recover fully over a couple of weeks. Without treatment, death from toxicity occurs 4 to 18 days later.
Benzodiazepine overdose describes the ingestion of one of the drugs in the benzodiazepine class in quantities greater than are recommended or generally practiced. The most common symptoms of overdose include central nervous system (CNS) depression, impaired balance, ataxia, and slurred speech. Severe symptoms include coma and respiratory depression. Supportive care is the mainstay of treatment of benzodiazepine overdose. There is an antidote, flumazenil, but its use is controversial.
Jeffrey A. Brent is a medical toxicologist who is a distinguished clinical professor of medicine and emergency medicine at the University of Colorado, School of Medicine. In addition, he is a professor at the Department of Environmental and Occupational Health at the Colorado School of Public Health. He is also the past president of the American Academy of Clinical Toxicology, was editor in chief of the journal Toxicological Reviews, and was a member of the board of directors of the American College of Medical Toxicology. Previously, most of Brent's research focused on the use of fomepizole as a treatment for both methanol and ethylene glycol poisoning, and he led a trial of this drug which resulted in the FDA approving it in December 1997. Currently, Brent serves as Director of the Toxicology Investigators Consortium, an NIH and FDA supported multi center research and surveillance group. Brent is also a senior editor of "Critical Care Toxicology: Diagnosis and Management of the Critically Poisoned Patient," originally published in 2005, and now in its second edition, which was published in 2017.
Steven A. Seifert was an American medical toxicologist. He was a professor of emergency medicine at the University of New Mexico, as well as the medical director of the New Mexico Poison and Drug Information Center. Since 2017, he was the editor-in-chief of Clinical Toxicology. He was also a jazz tenor saxophonist.
Although several medications have been approved in different countries as of April 2022, not all countries have these medications. Patients with mild to moderate symptoms who are in the risk groups can take nirmatrelvir/ritonavir or remdesivir, either of which reduces the risk of serious illness or hospitalization. In the US, the Biden Administration COVID-19 action plan includes the Test to Treat initiative, where people can go to a pharmacy, take a COVID test, and immediately receive free Paxlovid if they test positive.
Barry H. Rumack is an American medical toxicologist and pediatrician. His primary clinical and research interest has been in clinical toxicology with a special interest in acetaminophen poisoning. Since 2014 he is emeritus professor of emergency medicine and pediatrics at the University of Colorado School of Medicine.
ReSPECT stands for Recommended Summary Plan for Emergency Care and Treatment. It is an emergency care and treatment plan (ECTP) used in parts of the United Kingdom, in which personalized recommendations for future emergency clinical care and treatment are created through discussion between health care professionals and a person. These recommendations are then documented on a ReSPECT form.
Chloroquine and hydroxychloroquine are anti-malarial medications also used against some auto-immune diseases. Chloroquine, along with hydroxychloroquine, was an early experimental treatment for COVID-19. Neither drug prevents SARS-CoV-2 infection.
Onyema Eberechukwu Ogbuagu is an American-born infectious diseases physician, educator, researcher, and clinical trial investigator, who was raised and educated in Nigeria. He is an associate professor at Yale School of Medicine in New Haven, CT and is the director of the Yale AIDS Program clinical trials unit. His research contributions have focused on HIV/AIDS prevention and COVID-19 vaccination and treatment clinical trials. He switched his focus at the beginning of the 2019 COVID pandemic and participated as a principal investigator (PI) on the Pfizer-BioNtech COVID-19 vaccine trials and the Remdesivir SIMPLE trial in 2020 and 2021. In pursuit of his global health component of his career, Ogbuagu also supports postgraduate physician medical education programs in low and middle income countries in sub-Saharan Africa in Rwanda (2013–2018) and Liberia as well as HIV treatment programs in Liberia.