Jugular foramen syndrome

Jugular foramen syndrome
Human brain inferior view showing cranial nerves

Jugular foramen syndrome, or Vernet's syndrome, is characterized by paresis of the glossopharyngeal, vagal, and accessory (with or without the hypoglossal) nerves. ^{[1] [2]}

Symptoms

Symptoms of this syndrome are consequences of this paresis. As such, an affected patient may show:^{[ citation needed ]}

• dysphonia/hoarseness
• soft palate drooping
• deviation of the uvula towards the normal side
• dysphagia
• loss of sensory function from the posterior 1/3 of the tongue (CN IX)
• decrease in the parotid gland secretion (CN IX)
• loss of gag reflex
• sternocleidomastoid and trapezius muscles paresis (CN XI)

Causes

• Glomus tumors (most frequently)
• Meningiomas
• Schwannomas (Acoustic neuroma)
• Metastatic tumors located at the cerebellopontine angle
• Trauma
• Fracture of occipital bone
• Infections
• Cholesteatoma (very rare)
• Obstruction of the jugular foramen due to bone diseases
• Nasopharyngeal carcinoma spreading into the parapharyngeal space involving the ninth, tenth, and eleventh cranial nerves

Diagnosis

• Gadolinium-enhanced MRI for vestibular schwannoma
• MRI and biopsy for nasopharyngeal carcinoma
• Based on nerve palsies
• NCCT for occipital bone fracture

References

1. Erol, Fatih Serhat; Kaplan, Metin; Kavakli, Ahmet; Ozveren, M. Faik (June 2005). "Jugular foramen syndrome caused by choleastatoma" . Clinical Neurology and Neurosurgery. 107 (4): 342–346. doi:10.1016/j.clineuro.2004.08.006. PMID   15885397.
2. Quinones-Hinojosa, Alfredo, ed. (2012). Schmidek and Sweet Indications, Methods and Results (Expert Consult - Online and Print) (6th ed.). London: Elsevier Health Sciences. p. 2337. ISBN   9781455723287.