Maybelle "May" Parker-Jameson, commonly known as Aunt May, is a fictional character appearing in American comic books published by Marvel Comics, commonly in association with the superhero Spider-Man. Making her first full appearance in Amazing Fantasy #15, the character was created by writer Stan Lee and artist Steve Ditko, playing an influential role in the Spider-Man comic books.
Gwendolyne Maxine "Gwen" Stacy is a character appearing in American comic books published by Marvel Comics, usually as a supporting character in those featuring Spider-Man. A college student and the daughter of George and Helen Stacy, she was the first romantic interest for Peter following his high school graduation before she was murdered by the Green Goblin. Her death has haunted Peter ever since, and stories published long afterwards indicate she still holds a special place in his heart. Gwen was posthumously subjected to numerous cloning experiments by her former professor Miles Warren, Peter's clone Ben Reilly, and an A.I. of Harry Osborn, the latter resulting in the creation of the Kindreds, and Ben briefly resurrecting Gwen in "Dead No More: The Clone Conspiracy" (2016–2017), with the embodiment of Death herself confirming in Ben Reilly: The Scarlet Spider (2017–2018) that all clones Ben created of deceased people had their souls intact on being brought back, while clones of living people had unique souls of their own. In the alternate realities of Ultimate Marvel and Spider-Gwen, a still-living Gwen respectively becomes their universe's versions of Carnage and Spider-Woman.
Electro is the name of two supervillains appearing in American comic books published by Marvel Comics.
Kraven the Hunter is a supervillain appearing in American comic books published by Marvel Comics. Created by writer Stan Lee and artist Steve Ditko, the character first appeared in The Amazing Spider-Man #15 as an adversary for the superhero Spider-Man. He since endured as one of the web-slinger's most formidable foes, and is part of the collective of adversaries that make up Spider-Man's rogues' gallery. Kraven has also come into conflict with other heroes, such as Black Panther and Tigra. He is the half-brother of the Chameleon and is one of the founding members of the Sinister Six.
Doctor Octopus, also known as Doc Ock for short, is a fictional character appearing in American comic books published by Marvel Comics. The character was created by Stan Lee and Steve Ditko and first appeared in The Amazing Spider-Man #3. He is a highly intelligent, myopic, and stocky mad scientist who sports four strong and durable appendages resembling an octopus's tentacles, which extend from his body and can be used for various purposes. After his mechanical harness became permanently fused to his body during a laboratory accident, he turned to a life of crime, and came into conflict with the superhero Spider-Man. He has endured as one of Spider-Man's most prominent villains, and is regarded as one of his three archenemies, alongside the Green Goblin and Venom. He is the founder and leader of the Sinister Six, the first supervillain team to oppose Spider-Man.
The Lizard is a character appearing in American comic books published by Marvel Comics. Created by Stan Lee and Steve Ditko, he first appeared in The Amazing Spider-Man #6 as an enemy of the superhero Spider-Man. While the character has retained this role throughout most of his subsequent appearances, he has also been portrayed as a tragic antihero and occasional ally of Spider-Man. Connors is sometimes an ally of Spider-Man just as himself, and not necessarily as his alter ego.
Harold Theopolis "Harry" Lyman is a character appearing in American comic books published by Marvel Comics, commonly in association with the superhero Spider-Man. Created by Stan Lee and Steve Ditko, the character first appeared in The Amazing Spider-Man #31.
Benjamin "Ben" Reilly, also known as the Scarlet Spider, is a superhero appearing in American comic books published by Marvel Comics. Grown in a lab by Miles Warren/Jackal, he is a clone of Peter Parker/Spider-Man tasked with fighting him but instead becoming an ally, later even regarded as a "brother". Created by writer Gerry Conway, the character first appeared in The Amazing Spider-Man #149 and is seemingly killed in the same issue. The character returned and featured prominently in the 1994–96 "Clone Saga" storyline, adopting the "Scarlet Spider" alias with a costume similar to Spider-Man's consisting of a red spandex bodysuit and mask complemented by a blue sleeveless hoodie sweatshirt adorned with a large spider symbol on both sides, along with a utility belt and bulkier web-shooters. This Scarlet Spider costume was designed by artist Tom Lyle. When Peter Parker temporarily left the Spider-Man role, Ben became the new Spider-Man while wearing a new costume variation designed by artist Mark Bagley. However, Reilly dies at the hands of Norman Osborn/Green Goblin, sacrificing himself to save Parker who then resumes the Spider-Man role.
Edward "Ned" Leeds is a fictional character appearing in American comic books published by Marvel Comics. A supporting character in stories featuring the superhero Spider-Man, he has been a reporter for the Daily Bugle, and husband of Betty Brant. Leeds is one of the characters that appears under the mantle of the supervillain Hobgoblin; for a long time believed to be the first Hobgoblin, ten years following his assassination, he is retroactively established to have been the second Hobgoblin, brainwashed to serve as a stand-in for Roderick Kingsley and later left to be killed when he was no longer deemed necessary. The character was revived in a 2018–2022 storyline, with both Ned and Roderick brainwashed again by the Queen Goblin to serve as Hobgoblins. Synergetic with his MCU adaptation, Ned is revealed to be a sorcerer who trained with Baron Mordo to learn chaos magic, rewriting reality in an attempt to make himself the one-and-only Hobgoblin, archenemy of Spider-Man and lover of Natasha Romanoff.
The Jackal is an alias used by several supervillains appearing in American comic books published by Marvel Comics, usually depicted as enemies of the superhero Spider-Man. The original and best known incarnation, Miles Warren, was originally introduced in The Amazing Spider-Man #31 as a professor at the fictional Empire State University. Later storylines established him as also being a scientist researching genetics and biochemistry, and revealed an unhealthy romantic obsession he had for Gwen Stacy. Warren was driven mad with grief and jealousy so he created his Jackal alter-ego to seek revenge on Spider-Man, whom he blamed for Gwen's tragic death. To this end, he trained himself in martial arts, and created a green suit and gauntlets with claw-like razors. Although the Jackal initially didn't possess any superpowers, he later gained enhanced strength, speed and agility by mixing his genes with those of a jackal.
Silvermane is a supervillain appearing in American comic books published by Marvel Comics. A notorious crime boss and prominent figure in the Maggia, a fictional organized crime syndicate, he is usually depicted as an adversary of the superhero Spider-Man and the father of Joseph Manfredi. Silvermane later became a cyborg in an attempt to extend his lifespan.
Jean DeWolff is a character appearing in American comic books published by Marvel Comics. Created by writer Bill Mantlo and artist Sal Buscema, the character first appeared in Marvel Team-Up #48. Captain Jean DeWolff is a police detective from New York City. She is depicted as tough and unrelenting, the result of her difficult childhood and teenage years. She is a supporting character of the superhero Peter Parker / Spider-Man, for whom she secretly develops romantic feelings. She is also the sister of the original Wraith.
Molten Man is a fictional character appearing in American comic books published by Marvel Comics. Once a chemical engineer who longed to get rich, Mark Raxton was caught in an accident that saw his body get covered by an experimental organic-liquid metal alloy, which granted him superpowers, including the ability to generate extreme heat and radiation. Turning to a life of crime, he started off as an enemy of the superhero Spider-Man, but eventually was redeemed. He is also the stepbrother of Liz Allan.
Spencer Smythe is a supervillain appearing in American comic books published by Marvel Comics. The character is usually depicted as an adversary of the superhero Spider-Man as well as the father of Alistair Smythe. A scientist researching robotics and arachnids, he turned to crime to finance his research, and dedicated his life to capturing Spider-Man. He is best known for creating the Spider-Slayers, robots designed specifically to hunt down, capture, or kill the web-slinger.
The Green Goblin, a supervillain in Marvel Comics and an archenemy of the superhero Spider-Man, has been adapted in various forms of media, including films, television series, and video games.
Farley Stillwell is a fictional character appearing in American comic books published by Marvel Comics. He is a scientist best known for transforming Mac Gargan into the Scorpion.
"Dead No More: The Clone Conspiracy" is a 2016–17 Marvel Comics storyline starring Spider-Man. The story was notable for bringing long-dead Spider-Man supporting character Ben Reilly back to life. The storyline led Kaine to reclaim the heroic Scarlet Spider mantle and appear in his own comic book series. The story received generally mixed reviews, with critics praising the art style and action, however criticized the story and the retcons, as well as the treatment of Ben Reilly.
William "Billy" Connors is a fictional character appearing in American comic books published by Marvel Comics. He is usually depicted as a supporting character of Spider-Man, and the son of Dr. Curt Connors, also known as the Lizard. Much of his character's story deals with the trauma of his father's uncontrollable powers. Billy was later injected with Curt's Lizard Formula to cure him of a deadly virus, which also mutated him into an anthropomorphic lizard.
"Hunted" is a 2019 comic book storyline published by Marvel Comics, starring the character Spider-Man. It is a spiritual successor to the 1987 storyline "Kraven's Last Hunt". It involves the characters Spider-Man, Black Cat, Kraven the Hunter, Lizard, Vulture, and Taskmaster as well as the debut of the Last Son of Kraven.
