The National Institute of Allergy and Infectious Diseases is one of the 27 institutes and centers that make up the National Institutes of Health (NIH),an agency of the United States Department of Health and Human Services (HHS). NIAID's mission is to conduct basic and applied research to better understand,treat,and prevent infectious,immunologic,and allergic diseases.
The Influenza Genome Sequencing Project (IGSP),initiated in early 2004,seeks to investigate influenza evolution by providing a public data set of complete influenza genome sequences from collections of isolates representing diverse species distributions.
H5N1 clinical trials are clinical trials concerning H5N1 vaccines,which are intended to provide immunization to influenza A virus subtype H5N1. They are intended to discover pharmacological effects and identify any adverse reactions the vaccines may achieve in humans.
The National Emerging Infectious Diseases Laboratories (NEIDL) is a biosciences facility of Boston University located in the clinical and biopharma hub of the South End neighborhood of Boston,Massachusetts.
The Vaccine Research Center (VRC),is an intramural division of the National Institute of Allergy and Infectious Diseases (NIAID),part of the National Institutes of Health (NIH),US Department of Health and Human Services (HHS). The mission of the VRC is to discover and develop both vaccines and antibody-based products that target infectious diseases.
Bernard Moss is a virologist at the National Institute of Allergy and Infectious Diseases,part of the United States National Institutes of Health. He is the Chief of the NIAID Laboratory of Viral Diseases and of the NIAID Genetic Engineering Section. He is known for his work on poxviruses.
Julie E. Ledgerwood is an American allergist and immunologist,who is the chief medical officer and chief of the Clinical Trials Program at the Vaccine Research Center (VRC) of the National Institute of Allergy and Infectious Diseases (NIAID),part of the National Institutes of Health in Bethesda,Maryland. She is a Doctor of Osteopathic Medicine.
Stephen E. Straus was an American physician,immunologist,virologist and science administrator. He is particularly known for his research into human herpesviruses and chronic fatigue syndrome,and for his discovery of the autoimmune lymphoproliferative syndrome genetic disorder. He headed the Laboratory of Clinical Investigation of the National Institute of Allergy and Infectious Diseases,National Institutes of Health (NIH),and served as the founding director of the NIH's National Center for Complementary and Alternative Medicine.
A Zika virus vaccine is designed to prevent the symptoms and complications of Zika virus infection in humans. As Zika virus infection of pregnant women may result in congenital defects in the newborn,the vaccine will attempt to protect against congenital Zika syndrome during the current or any future outbreak. As of April 2019,no vaccines have been approved for clinical use,however a number of vaccines are currently in clinical trials. The goal of a Zika virus vaccine is to produce specific antibodies against the Zika virus to prevent infection and severe disease. The challenges in developing a safe and effective vaccine include limiting side effects such as Guillain-Barrésyndrome,a potential consequence of Zika virus infection. Additionally,as dengue virus is closely related to Zika virus,the vaccine needs to minimize the possibility of antibody-dependent enhancement of dengue virus infection.
Brian R. Murphy is an American virologist and former co-chief of the Laboratory of Infectious Diseases at the National Institute of Allergy and Infectious Disease.
Emmie de Wit is a Dutch-American virologist. She is chief of the molecular pathogenesis unit at the Rocky Mountain Laboratories. Her research combines pathogenesis studies with detailed molecular analyses to identify molecular determinants of severe respiratory tract disease within the virus and the host.
Andrea Marzi is a German-American virologist. She is chief of the immunobiology and molecular virology unit at the Rocky Mountain Laboratories. Marzi investigates the pathogenesis of filoviruses and vaccine development. She received the Loeffler-Frosch medal in recognition of her research.
Kizzmekia "Kizzy" Shanta Corbett is an American viral immunologist. She is an Assistant Professor of Immunology and Infectious Diseases at Harvard T.H. Chan School of Public Health and the Shutzer Assistant Professor at the Harvard Radcliffe Institute since June 2021.
Arnold Monto is an American physician and epidemiologist. At the University of Michigan School of Public Health,Monto is the Thomas Francis,Jr. Collegiate Professor Emeritus of Public Health,professor emeritus of both epidemiology and global public health,and co-director of the Michigan Center for Respiratory Virus Research &Response. His research focuses on the occurrence,prevention,and treatment of viral respiratory infections in industrialized and developing countries' populations.
Nancy Jean Sullivan is an American cell biologist,virologist,and immunologist. She has served as the director of the National Emerging Infectious Diseases Laboratories (NEIDL) at Boston University since December 2022. Previously,she was chief of the Biodefense Research Section at the Vaccine Research Center (VRC) in the National Institute of Allergy and Infectious Diseases (NIAID).
Patrizia Farci is an Italian scientist and hepatologist. She is chief of the hepatic pathogenesis section at the National Institute of Allergy and Infectious Diseases. Farci conducts translational research in the field of liver diseases,particularly in the study of pathogenesis of acute and chronic viral hepatitis. She was previously a full professor of medicine and director of the liver unit and the postgraduate school of gastroenterology at the University of Cagliari.
Vanessa M. Hirsch is a Canadian-American veterinary pathologist and scientist. She is a senior investigator and chief of the nonhuman primate virology section at the National Institute of Allergy and Infectious Diseases. Hirsch researches AIDS pathogenesis,the evolution and origins of primate lentiviruses,and HIV vaccine development.
John Ring La Montagne was a Mexican-American biomedical scientist who served as the deputy director of the National Institute of Allergy and Infectious Diseases from 1998 to 2004. He specialized in viral vaccines,HIV/AIDS research,and oversaw NIH's biodefense research after the September 11 attacks.
John R. Mascola is an American physician-scientist,immunologist and infectious disease specialist. He was the director of the Vaccine Research Center (VRC),part of the National Institute of Allergy and Infectious Diseases (NIAID),National Institutes of Health (NIH). He also served as a principal advisor to Anthony Fauci,director of NIAID,on vaccines and biomedical research affairs. Mascola is the current Chief Scientific Officer for ModeX Therapeutics.
Kanta Subbarao is an Indian virologist,molecular geneticist,and physician-scientist. She is director of the World Health Organization collaborating centre for reference and research on influenza. Subbarao is also a professor at the Doherty Institute.
