Route 43 is a highway in western Missouri. Its northern terminus is at U.S. Route 54 midway between Nevada and Deerfield. Its southern terminus is at the corner of Missouri, Arkansas, and Oklahoma where it continues down the Arkansas/Oklahoma state line as both Arkansas Highway 43 and Oklahoma State Highway 20.
Route 19 is a long state highway in Missouri. Its northern terminus is at U.S. Route 61 in New London and its southern terminus is at U.S. Route 63 on the north side of Thayer. Route 19 is one of Missouri's original 1922 highways, though it initially had a northern terminus at Route 14 in Cuba and was later extended north.
Route 21 is a highway in eastern Missouri. Its northern terminus is at Route 30 in Affton. Its southern terminus is at the Arkansas state line. In the St. Louis area, it is known as Tesson Ferry Road, which was named after the 19th century proprietor of the ferry across the Meramec River.
Route 94 serves eastern and central Missouri. The entire route closely parallels the Missouri River. The eastern terminus is at U.S. Route 67 in West Alton; its western terminus is at the intersection of U.S. Route 54 and U.S. Route 63 in Jefferson City.
Route 283 was a short highway in the Kansas City, Missouri regional area. Its northern terminus was at Interstate 29 (I-29) and U.S. Route 71 (US 71) in Kansas City; its southern terminus was at Route 9 at the northern city limit of North Kansas City. It was known locally as North Oak Trafficway.
Route 116 is a highway in northwestern Missouri. Its eastern terminus is at Route A in Braymer; its western terminus is at U.S. Route 59 in Rushville.
Route 9 is a highway in the Kansas City, Missouri area. Its northern terminus is at Interstate 29/U.S. Route 71 in Kansas City North; its southern terminus is at Interstate 35/Interstate 70/U.S. Route 24/U.S. Route 40 in downtown Kansas City. Even though both termini are in Kansas City, it passes through other towns and cities. It is carried across the Missouri River by the Heart of America Bridge between downtown Kansas City, Missouri and North Kansas City, Missouri. In North Kansas City, the highway serves as a main thoroughfare, Burlington Street.
Route 34 is a highway in southeastern Missouri. Its eastern terminus is at the Illinois state line on the Mississippi River at Cape Girardeau where it overlaps Route 74. Its western terminus is at U.S. Route 60 near Van Buren. The road continues into Illinois as Illinois Route 146.
Route 80 is a state highway in southeastern Missouri. The route is located in northern New Madrid and central Mississippi Counties.
Route 58 is a highway in western Missouri. Its eastern terminus is at U.S. Route 50 west of Warrensburg; its western terminus is at Route D west of Belton, Missouri. It is one of only a very few highways to end at a state supplemental route.
Route 109 is a state highway in St. Louis County, Missouri and Jefferson County, Missouri. Its northern terminus is at Wild Horse Creek Road in Chesterfield; its southern terminus is at Routes W and FF in Jefferson County. The road continues north, curves around Spirit of St. Louis Airport and connects with Chesterfield Airport Road, providing a "backway" to the Chesterfield area.
Route 113 is a highway in northwestern Missouri. Its northern terminus is at U.S. Route 136 in Burlington Junction; its southern terminus is at U.S. Route 59 east of Mound City.
Route 41 is a highway in central Missouri. Its northern terminus is at U.S. Route 24 in southern Carroll County; its southern terminus is at Interstate 70/U.S. Route 40 west of Boonville, where the road continues south as Route 135.
Route 87 is a highway in central Missouri. Its southern terminus is at U.S. Route 54 in Eldon, and its northern terminus is at Route 5/240 in Glasgow. Parts of the road are overlapped by the Lewis and Clark Trail and Santa Fe Trail.
Route 33 is a highway in western Missouri. Its northern terminus is at Route 6 in Maysville; its southern terminus is at U.S. Route 69 in Liberty.
Route 47 is a highway in eastern Missouri. Its northern terminus is at Route 79 near Winfield; its southern terminus is at U.S. Route 67 in Bonne Terre.
Route 110 is a short highway in Jefferson County. Its eastern terminus is at U.S. Route 67 about six miles (10 km) east of De Soto; its western terminus is at Route 21 a few miles north of De Soto. De Soto and Olympian Village are the only cities on the route.
Route 88 was a 6.8-mile-long (10.9 km) state highway located entirely within the city limits of Springfield. Its western terminus was at Sunshine Street. Its eastern terminus was at Glenstone Avenue. It was a collection of older highways which were still under state maintenance.
US 54 / Route B in Jefferson City
Route 98 east of Boonville 
