N-methyl-2-oxoglutaramate hydrolase

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N-methyl-2-oxoglutaramate hydrolase
Identifiers
EC no. 3.5.1.36
CAS no. 9073-53-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
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PMC articles
PubMed articles
NCBI proteins

In enzymology, a N-methyl-2-oxoglutaramate hydrolase (EC 3.5.1.36) is an enzyme that catalyzes the chemical reaction

N-methyl-2-oxoglutaramate + H2O 2-oxoglutarate + methylamine

Thus, the two substrates of this enzyme are N-methyl-2-oxoglutaramate and H2O, whereas its two products are 2-oxoglutarate and methylamine.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-methyl-2-oxoglutaramate methylamidohydrolase. This enzyme is also called 5-hydroxy-N-methylpyroglutamate synthase.

References