Interstate 77 (I-77) is a north–south Interstate Highway in the Eastern United States. It traverses diverse terrain, from the mountainous state of West Virginia to the rolling farmlands of North Carolina and Ohio. It largely supplants the old U.S. Route 21 (US 21) between Cleveland, Ohio, and Columbia, South Carolina, as an important north–south corridor through the middle Appalachian Mountains. The southern terminus of I-77 is in Cayce, South Carolina, in Lexington County at the junction with I-26. The northern terminus is in Cleveland at the junction with I-90. Other major cities that I-77 connects to include Columbia, South Carolina; Charlotte, North Carolina; Charleston, West Virginia; and Akron, Ohio. The East River Mountain Tunnel, connecting Virginia and West Virginia, is one of only two instances in the U.S. where a mountain road tunnel crosses a state line. The other is the Cumberland Gap Tunnel, connecting Tennessee and Kentucky. I-77 is a snowbird route to the Southern U.S. for those traveling from the Great Lakes region.
Interstate 71 (I-71) is a north–south Interstate Highway in the midwestern and southeastern regions of the United States. Its southern terminus is at an interchange with I-64 and I-65 in Louisville, Kentucky, and its northern terminus at an interchange with I-90 in Cleveland, Ohio. I-71 runs concurrently with I-75 from a point about 20 miles (32 km) south of Cincinnati, Ohio, into Downtown Cincinnati. While most odd numbered Interstates run north–south, I-71 takes more of a northeast–southwest course, with some east–west sections, and is mainly a regional route serving Kentucky and Ohio. It links I-80 and I-90 to I-70 and ultimately links to I-40. Major metropolitan areas served by I-71 include Louisville, Cincinnati, Columbus, and Cleveland.
State Route 21 (SR 21) is a north–south state highway in northeastern Ohio. The southern terminus is north of Strasburg on U.S. Route 250. The northern terminus is at an interchange with Interstate 77 in Cuyahoga Heights.
Interstate 271 (I-271) is an auxiliary Interstate Highway in the suburbs of Cleveland and Akron in the US state of Ohio. The highway is officially designated the Outerbelt East Freeway but is rarely referred to by that name by locals, instead simply referring to it as "271".
U.S. Route 35 (US 35) is a United States Highway that runs southeast-northwest for approximately 412 miles (663 km) from the western suburbs of Charleston, West Virginia to northern Indiana. Although the highway is physically southeast-northwest, it is nominally north–south. The highway's southern terminus is in Teays Valley, West Virginia, near Scott Depot, at Interstate 64 (I-64). Its northern terminus is near Michigan City, Indiana, at US 20. The West Virginia portion of the highway is mostly expressway, becoming a freeway shortly before it crosses the Ohio River into Ohio. The Ohio portion has been upgraded to a four-lane highway/freeway between the West Virginia state line and Trotwood, west of Dayton.
U.S. Route 322 is a 494-mile-long (795.0 km), east–west United States Highway, traversing Ohio, Pennsylvania, and New Jersey. The road is a spur of US 22 and one of the original highways from 1926. A portion of it at one time was concurrent with the Lakes-to-Sea Highway.
State Route 59 is an east–west state highway in the U.S. state of Ohio, serving the Akron metropolitan area. The western terminus of State Route 59 is in downtown Akron at a partial interchange with the Interstate 76/Interstate 77 concurrency, and the eastern terminus is at State Route 5, 0.5 miles (0.80 km) east of Ravenna. The route is approximately 23 miles (37 km) long and was certified in 1969 over what had previously been part of SR 5. It serves as a major or as the primary east–west roadway for the cities of Cuyahoga Falls, Kent, Ravenna, and Stow, the village of Silver Lake, and Franklin and Ravenna Townships.
Interstate 76 (I-76) is an east–west Interstate Highway in the Eastern United States. The highway runs approximately 435.66 miles (701.13 km) from an interchange with I-71 west of Akron, Ohio, east to I-295 in Bellmawr, New Jersey. This route is not contiguous with I-76 in Colorado and Nebraska.
Interstate 490 (I-490) is a 2.43-mile (3.91 km) auxiliary Interstate Highway in Cleveland, Ohio. The western terminus is a junction with I-90 and I-71 on Cleveland's west side. After spanning the Cuyahoga River, I-490 reaches its eastern terminus at a junction with East 55th Street, just east of I-77.
Interstate 480 (I-480) is a 41.77-mile-long (67.22 km) auxiliary Interstate Highway of I-80 in the US state of Ohio that passes through much of the Greater Cleveland area, including the southern parts of the city of Cleveland. I-480 is one of 13 auxiliary Interstate Highways in the state. The western terminus of I-480 is an interchange with I-80 and the Ohio Turnpike in North Ridgeville. Starting east through suburban Lorain County, I-480 enters Cuyahoga County, then approaches Cleveland Hopkins International Airport, which serves as the primary airport for Northeast Ohio. After traversing Brooklyn and crossing the Cuyahoga River on the Valley View Bridge, the highway continues east toward the communities of Bedford and Twinsburg toward its eastern terminus at I-80 and the Ohio Turnpike in Streetsboro. On its route, I-480 crosses I-71 and I-77 and is concurrent with I-271 for approximately four miles (6.4 km). In 1998, the governor of Ohio, George Voinovich, gave I-480 the additional name of the "Senator John Glenn Highway", in honor of the former NASA astronaut and US senator from Ohio for 24 years.
U.S. Route 422 (US 422) is a 271-mile-long (436 km) spur route of US 22 split into two segments in the U.S. states of Ohio and Pennsylvania. The western segment of US 422 runs from downtown Cleveland, Ohio, east to Ebensburg, Pennsylvania. The eastern segment, located entirely within Pennsylvania, runs from Hershey east to King of Prussia, near Philadelphia. US 422 Business serves as a business route into each of four towns along the way.
Ohio State Route 176 is a route linking Interstate 71 (I-71) in Cleveland to I-77 near Richfield. The freeway portion is known as the Jennings Freeway, while the at-grade portion is mostly Broadview Road.
State Route 532 is a north–south state highway in the northeastern portion of the U.S. state of Ohio. The highway runs from its southern terminus at a signalized intersection with U.S. Route 224 (US 224) on the Summit–Portage county line approximately 0.75 miles (1.21 km) south of Mogadore on the border of Springfield Township and Suffield Township to its northern terminus at a diamond interchange with Interstate 76 (I-76), at its exit 29 within the Tallmadge city limits.
State Route 237 is a nearly 14-mile (23 km) north–south signed route in Cuyahoga County, Ohio. Its southern terminus is at SR 82 in Strongsville, and its northern terminus is in Lakewood where U.S. Route 20 (US 20) joins the US 6 / SR 2 concurrency.
The Ohio Department of Transportation is the administrative department of the Ohio state government responsible for developing and maintaining all state and U.S. roadways outside of municipalities and all Interstates except the Ohio Turnpike. In addition to highways, the department also helps develop public transportation and public aviation programs. ODOT is headquartered in Columbus, Ohio. Formerly, under the direction of Michael Massa, ODOT initiated a series of interstate-based Travel Information Centers, which were later transferred to local sectors. The Director of Transportation is part of the Governor's Cabinet.
Interstate 80 (I-80) in the US state of Ohio runs across the northern part of the state. Most of the route is part of the Ohio Turnpike; only an 18.78-mile (30.22 km) stretch is not part of the toll road. That stretch of road is the feeder route to the Keystone Shortway, a shortcut through northern Pennsylvania that provides access to New York City.
Interstate 77 (I-77) in Ohio is an Interstate Highway that runs for 163.03 miles (262.37 km) through the state. The highway crosses into Ohio on the Marietta–Williamstown Interstate Bridge over the Ohio River near Marietta. The northern terminus is in Cleveland at the junction with I-90. From the West Virginia state line to Cleveland, I-77 serves the cities of Marietta, Cambridge, New Philadelphia, Canton, Akron, and the Cleveland suburban city of Brecksville.
Interstate 90 (I-90) runs east–west across the northern tier of the US state of Ohio. Much of it is along the Ohio Turnpike, but sections outside the turnpike pass through Cleveland and northeast into Pennsylvania.
Interstate 75 (I-75) runs from Cincinnati to Toledo by way of Dayton in the US state of Ohio. The highway enters the state running concurrently with I-71 from Kentucky on the Brent Spence Bridge over the Ohio River and into the Bluegrass region. I-75 continues along the Mill Creek Expressway northward to the Butler County line just north of I-275. From there, the freeway runs into the Miami Valley and then passes through the Great Black Swamp before crossing into Michigan.
State Route 175 (SR 175) is a 15.70-mile (25.27 km) long north–south state highway in the northeastern part of the U.S. state of Ohio. The southern terminus of SR 175 is at a signalized intersection with SR 43 in Solon. Its northern terminus is at a signalized intersection with SR 283 in Euclid.
I-76 / I-77 in Akron 
US 6 / US 20 / US 422 / SR 14 / SR 43 / SR 87 at Public Square in Cleveland
