P-Toluic acid

p-Toluic acid

Names
Preferred IUPAC name 4-Methylbenzoic acid
Other names para-toluic acid p-toluic acid para-methylbenzoic acid p-methylbenzoic acid toluene-4-carboxylic acid crithminic acid
Identifiers
CAS Number	99-94-5  Y
3D model (JSmol)	Interactive image
Beilstein Reference	3904552
ChEBI	CHEBI:36635
ChEMBL	ChEMBL21708  Y
ChemSpider	7190  Y
ECHA InfoCard	100.002.549
EC Number	202-803-3
KEGG	C01454  Y
PubChem CID	7470
RTECS number	XU1575000
UNII	A26GBX5SSV  Y
CompTox Dashboard (EPA)	DTXSID6021618
InChI InChI=1S/C8H8O2/c1-6-2-4-7(5-3-6)8(9)10/h2-5H,1H3,(H,9,10) Y Key: LPNBBFKOUUSUDB-UHFFFAOYSA-N Y InChI=1/C8H8O2/c1-6-2-4-7(5-3-6)8(9)10/h2-5H,1H3,(H,9,10) Key: LPNBBFKOUUSUDB-UHFFFAOYAB
SMILES O=C(O)c1ccc(cc1)C
Properties
Chemical formula	C8H8O2
Molar mass	136.150 g·mol−1
Appearance	Crystalline solid
Density	1.06g/mL
Melting point	180 to 181 °C (356 to 358 °F; 453 to 454 K) [1]
Boiling point	274 to 275 °C (525 to 527 °F; 547 to 548 K) [1]
Solubility in water	Sparingly soluble in hot water
Thermochemistry
Std enthalpy of formation (ΔfH⦵298)	−429 kJ/mol
Std enthalpy of combustion (ΔcH⦵298)	3862 kJ/mol
Hazards
GHS labelling:
Pictograms
Signal word	Warning
Hazard statements	H302, H315, H317, H319, H335
Precautionary statements	P261, P264, P270, P271, P272, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P333+P313, P337+P313, P362, P363, P403+P233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y  verify  (what is  YN ?) Infobox references

p-Toluic acid (4-methylbenzoic acid) is a substituted benzoic acid with the formula CH₃C₆H₄CO₂H. It is a white solid that is poorly soluble in water but soluble in acetone. A laboratory route to p-toluic acid involves oxidation of p-cymene with nitric acid. ^[2]

Role in production of terephthalic acid

p-Toluic acid is an intermediate in the conversion of p-xylene to terephthalic acid, a commodity chemical used in the manufacture of polyethylene terephthalate. It is generated both by the oxidation of p-xylene as well as the hydrogenolysis of 4-carboxybenzaldehyde. In related processes it is converted to methyl p-toluate, which is oxidized to monomethyl terephthalate. ^[3]

p-Toluic acid is an intermediate in the production of terephthalic acid.

See also

• o-Toluic acid
• m-Toluic acid

References

1. Merck Index , 12th Edition, 9673
2. W. F. Tuley; C. S. Marvel (1947). "p-Toluic Acid". Org. Synth. 27: 86. doi:10.15227/orgsyn.027.0086.
3. Tomas, Rogerio A. F.; Bordado, Joao C. M.; Gomes, Joao F. P. (2013). "p-Xylene Oxidation to Terephthalic Acid: A Literature Review Oriented toward Process Optimization and Development". Chemical Reviews. 113 (10): 7421–7469. doi:10.1021/cr300298j. PMID   23767849.

External links

Material Safety Data Sheet