Pentachloroaniline

Pentachloroaniline

Names
Preferred IUPAC name 2,3,4,5,6-pentachloroaniline
Other names Benzenamine, pentachloroaminobenzene [1]
Identifiers
CAS Number	527-20-8  Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL1904605
ChemSpider	10243
ECHA InfoCard	100.007.647
EC Number	208-410-3
PubChem CID	10693
UNII	UW5QVL647I  Y
CompTox Dashboard (EPA)	DTXSID4037584
InChI InChI=1S/C6H2Cl5N/c7-1-2(8)4(10)6(12)5(11)3(1)9/h12H2 Key: KHCZSJXTDDHLGJ-UHFFFAOYSA-N
SMILES C1(=C(C(=C(C(=C1Cl)Cl)Cl)Cl)Cl)N
Properties
Chemical formula	C6H2Cl5N
Molar mass	265.34 g·mol−1
Appearance	yellow crystalline solid
Density	1.75 g/cm³
Melting point	−43.8 °C (−46.8 °F; 229.3 K)
Boiling point	81.6 °C (178.9 °F; 354.8 K)
Solubility in water	practically insoluble
Hazards
GHS labelling:
Pictograms	[2]
Signal word	Danger
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Pentachlorotoluene is a chemical compound from the group of chloroanilines. Its chemical formula is C₆H₂Cl₅N. ^[3] Pentachloroaniline occurs as a derivative of pentachloronitrobenzene. ^{[4] [5]}

Synthesis

Pentachloroaniline can be obtained by reducing pentachloronitrobenzene with tin, hydrochloric acid, and ethanol. It is also formed by the action of chlorine on an ethereal solution of symmetrical m-dichloroaniline. ^[6]

Physical characteristics

Pentachloroaniline is a yellow crystalline solid, practically insoluble in water, but readily dissolves in organic solvents. Highly flammable.

Uses

Pentachloroaniline is highly important in the industrial field, where it is utilized in various ways. Belonging to the aniline group, which comprises substances such as aniline and chloroanilines, it is employed as a dye and as an intermediate in the synthesis of plasticizers and pesticides. Additionally, it is involved in rubber production and functions as a flame retardant. ^[7]

See also

• Hexachlorobenzene
• Pentabromotoluene
• Pentachlorobenzene
• Pentafluorotoluene

References

1. Informatics, NIST Office of Data and. "2,3,4,5,6-Pentachloroaniline". webbook.nist.gov. Retrieved 23 April 2025.
2. "Pentachloroaniline". accustandard.com. Retrieved 23 April 2025.
3. "NCATS Inxight Drugs — PENTACHLOROANILINE". drugs.ncats.io. Retrieved 23 April 2025.
4. "Pentachloroaniline". sitem.herts.ac.uk. Retrieved 23 April 2025.
5. "Pentachloroaniline". Sigma Aldrich . Retrieved 23 April 2025.
6. Erlenmeyer, Emil (1894). Lehrbuch der organischen Chemie (in German). C.F. Winter'sche Verlagshandlung. p. 743. Retrieved 23 April 2025.
7. "Pentachloroaniline | CAS 527-20-8 | SCBT - Santa Cruz Biotechnology". scbt.com . Retrieved 23 April 2025.