Peptidyl-glutaminase

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peptidyl-glutaminase
Identifiers
EC no. 3.5.1.43
CAS no. 37228-70-9
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In enzymology, a peptidyl-glutaminase (EC 3.5.1.43) is an enzyme that catalyzes the chemical reaction

alpha-N-peptidyl-L-glutamine + H2O alpha-N-peptidyl-L-glutamate + NH3

Thus, the two substrates of this enzyme are alpha-N-peptidyl-L-glutamine and H2O, whereas its two products are alpha-N-peptidyl-L-glutamate and NH3.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is peptidyl-L-glutamine amidohydrolase. Other names in common use include peptidoglutaminase I, peptideglutaminase, and peptidoglutaminase.

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References