Prostaglandin E

Prostaglandin E

PGE1 (alprostadil) - top PGE2 (dinoprostone) - bottom
Clinical data
ATC code	G02AD ( WHO )
Identifiers
CAS Number	11042-70-9
ChemSpider	none

Prostaglandin E is a family of naturally occurring prostaglandins that are used as medications.

Types include:

• Prostaglandin E₁ also known as alprostadil
• Prostaglandin E₂ also known as dinoprostone

Both types are on the World Health Organization's List of Essential Medicines. ^[1]

Prostaglandin E play an important role in thermoregulation of the human brain. Decreased formation of prostaglandin E through inhibition of cyclooxygenase is the basis for the antipyretic of nonsteroidal anti-inflammatory drugs (NSAIDs).

References

1. World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl: 10665/325771 . WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.

External links

• "Alprostadil". Drug Information Portal. U.S. National Library of Medicine. Archived from the original on July 13, 2016.
• "Dinoprostone". Drug Information Portal. U.S. National Library of Medicine. Archived from the original on June 28, 2019.
• Prostaglandins+E at the U.S. National Library of Medicine Medical Subject Headings (MeSH)