Prostaglandin E

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Prostaglandin E
Alprostadil.svg
Dinoprostone.png
PGE1 (alprostadil) - top
PGE2 (dinoprostone) - bottom
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Prostaglandin E is a family of naturally occurring prostaglandins that are used as medications.

Types include:

Both types are on the World Health Organization's List of Essential Medicines. [1]

Prostaglandin E play an important role in thermoregulation of the human brain. Decreased formation of prostaglandin E through inhibition of cyclooxygenase is the basis for the antipyretic of nonsteroidal anti-inflammatory drugs (NSAIDs).

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References

  1. World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl: 10665/325771 . WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.