Prototheca

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Prototheca
Prototheca wickerhamii.gif
Prototheca wickerhamii, with Gram stain
Scientific classification OOjs UI icon edit-ltr.svg
Clade: Viridiplantae
Division: Chlorophyta
Class: Trebouxiophyceae
Order: Chlorellales
Family: Chlorellaceae
Genus: Prototheca
Krüger, 1894 [1]
Species [2]

Prototheca is a genus of algae in the family Chlorellaceae. [3] While this genus is a member of the green algae, all Prototheca no longer have chloroplasts and therefore their photosynthetic ability. Some species can cause protothecosis in humans and various vertebrates.

Contents

Etymology

From the Greek proto- (first) + thēkē (sheath), Prototheca is a genus of variably shaped spherical cells of achloric algae in the family Chlorellaceae. Wilhelm Krüger, a German expert in plant physiology and sugar production, reported Prototheca microorganisms in 1894, shortly after spending 7 years in Java studying sugarcane. He isolated Prototheca species from the sap of 3 tree species. Krüger named these organisms as P. moriformis and P. zopfii, the second name as a tribute to Friedrich Wilhelm Zopf, a renowned botanist, mycologist, and lichenologist. [4]

Biology

Prototheca consists of microscopic, single cells, which may sometimes be clustered to form irregular packets. The cell is generally spherical, ellipsoidal or reniform in shape, with a thin and delicate cell wall. Chloroplasts are absent. [5]

With the lack of chloroplasts and photosynthetic ability, Prototheca grow heterotrophically and some exhibit parasitism. Other groups of photosynthetic organisms have undergone similar functional losses in photosynthetic ability and shifted to a parasitic lifestyle, such as in apicomplexans.

Evolution and taxonomy

Although Prototheca lack chloroplasts, they were recognized early on as closely related to other Chlorellaceae based on other morphological and physiological traits similar to the group. [6] [7] Phylogenetics confirm that Prototheca species are closely related to Chlorella and other genera, although it is not yet clear whether Prototheca is a monophyletic group. [8]

Pathogenicity

Some species in the genus Prototheca are known to cause protothecosis, one of the few researched diseases caused by algae, which are categorized as Algaemia. P. wickerhamii is the main causing agent of protothecosis in humans, and was first identified as such in 1964. A strain of P. bovis (formerly classified under P. zopfii ) is known to cause this disease in cattle, dogs, buffalo, and horses. [9]

Symptoms include: Cutaneous lesions, Olecranon bursitis.

Related Research Articles

<span class="mw-page-title-main">Chlorophyta</span> Phylum of green algae

Chlorophyta is a division of green algae informally called chlorophytes.

<span class="mw-page-title-main">Green algae</span> Paraphyletic group of eukaryotes

The green algae are a group of chlorophyll-containing autotrophic eukaryotes consisting of the phylum Prasinodermophyta and its unnamed sister group that contains the Chlorophyta and Charophyta/Streptophyta. The land plants (Embryophytes) have emerged deep within the charophytes as a sister of the Zygnematophyceae. Since the realization that the Embryophytes emerged within the green algae, some authors are starting to include them. The completed clade that includes both green algae and embryophytes is monophyletic and is referred to as the clade Viridiplantae and as the kingdom Plantae. The green algae include unicellular and colonial flagellates, most with two flagella per cell, as well as various colonial, coccoid (spherical), and filamentous forms, and macroscopic, multicellular seaweeds. There are about 22,000 species of green algae, many of which live most of their lives as single cells, while other species form coenobia (colonies), long filaments, or highly differentiated macroscopic seaweeds.

<span class="mw-page-title-main">Archaeplastida</span> Clade of eukaryotes containing land plants and some algae

The Archaeplastida are a major group of eukaryotes, comprising the photoautotrophic red algae (Rhodophyta), green algae, land plants, and the minor group glaucophytes. It also includes the non-photosynthetic lineage Rhodelphidia, a predatorial (eukaryotrophic) flagellate that is sister to the Rhodophyta, and probably the microscopic picozoans. The Archaeplastida have chloroplasts that are surrounded by two membranes, suggesting that they were acquired directly through a single endosymbiosis event by phagocytosis of a cyanobacterium. All other groups which have chloroplasts, besides the amoeboid genus Paulinella, have chloroplasts surrounded by three or four membranes, suggesting they were acquired secondarily from red or green algae. Unlike red and green algae, glaucophytes have never been involved in secondary endosymbiosis events.

<span class="mw-page-title-main">Trebouxiophyceae</span> Class of algae

The Trebouxiophyceae, also known as trebouxiophytes, are a class of green algae, in the division Chlorophyta. Members of this class are single-celled, colonial, or multicellular and are found in freshwater or terrestrial habitats worldwide. Many taxa in the Trebouxiophyceae form symbiotic relationships with other organisms; in particular, the majority of phycobionts within lichens are trebouxiophytes. A number of taxa have also lost the ability to photosynthesize, and have evolved to become parasitic; examples include Prototheca and Helicosporidium.

<span class="mw-page-title-main">Prasiolales</span> Order of algae

Prasiolales is an order of green algae in the class Trebouxiophyceae. Members of this order are ecologically widespread and are found in freshwater, marine, and terrestrial habitats from the Arctic to the Antarctic.

<span class="mw-page-title-main">Botryococcaceae</span> Family of algae

Botryococcaceae is a family of green algae in the class Trebouxiophyceae.

<span class="mw-page-title-main">Prasiolaceae</span> Family of algae

Prasiolaceae is a family of green algae in the order Prasiolales. Members of this family are found in freshwater, terrestrial, and marine habitats.

<span class="mw-page-title-main">Selenastraceae</span> Family of algae

Selenastraceae is a family of green algae in the order Sphaeropleales. Members of this family are common components of the phytoplankton in freshwater habitats worldwide. A few species have been found in brackish and marine habitats, such as in the Baltic Sea.

<i>Choricystis</i> Genus of algae

Choricystis is a genus of green algae in the class Trebouxiophyceae, considered a characteristic picophytoplankton in freshwater ecosystems. Choricystis, especially the type species Choricystis minor, has been proposed as an effective source of fatty acids for biofuels. Choricystis algacultures have been shown to survive on wastewater. In particular, Choricystis has been proposed as a biological water treatment system for industrial waste produced by the processing of dairy goods.

Dictyochloris is a genus of green algae in the class Chlorophyceae. It is the sole genus of the family Dictyochloridaceae. It is commonly found in terrestrial and subaerial habitats.

Dictyochloropsis is a genus of unicellular green alga of the phylum Chlorophyta. This genus consists of free-living algae which have a reticulate (net-like) chloroplast that varies slightly in morphology between species, and that when mature always lacks a pyrenoid. Dictyochloropsis is asexual and reproduces using autospores.

<i>Dictyosphaerium</i> Genus of algae

Dictyosphaerium is a genus of green algae, in the family Chlorellaceae. It occurs in freshwater habitats around the world and is planktonic. The name comes from the Greek roots diktyon, meaning "net", and sphaira, meaning "ball", referring to its morphology.

<i>Didymogenes</i> Genus of algae

Didymogenes is a genus of microscopic green algae in the class Trebouxiophyceae. It is a planktonic species found in freshwater habitats worldwide. Formerly placed in the family Scenedesmaceae, molecular studies have placed it in the family Chlorellaceae.

<i>Elliptochloris</i> Genus of algae

Elliptochloris is a genus of green algae in the order Prasiolales. Species of this genus are common and found in a variety of terrestrial habitats such as soils. Some species in the genus are photobiont partners in lichens. One species, E. marina, is a symbiont within two species of sea anemone, Anthopleura elegantissima and A. xanthogrammica. It seems to have a worldwide distribution.

<i>Geminella</i> (alga) Genus of algae

Geminella is a genus of green algae in the phylum Chlorophyta. Once considered part of the order Ulotrichales, molecular phylogenetics have shown that Geminella and related genera form a well-supported clade within the class Trebouxiophyceae.

<i>Helicosporidium</i> Genus of algae

Helicosporidium is a genus of colorless, pathogenic algae in the class Trebouxiophyceae of the green algae. It is a parasite found in the gut of insects, and a close relative of Prototheca.

<i>Trebouxia</i> Genus of algae

Trebouxia is a unicellular green alga. It is a photosynthetic organism that can exist in almost all habitats found in polar, tropical, and temperate regions. It can either exist in a symbiotic relationship with fungi in the form of lichen or it can survive independently as a free-living organism alone or in colonies. Trebouxia is the most common photobiont in extant lichens. It is a primary producer of marine, freshwater and terrestrial ecosystems. It uses carotenoids and chlorophyll a and b to harvest energy from the sun and provide nutrients to various animals and insects.

Algaemia is a secondary term that refers to the emerging condition in which green algae enter the bloodstream. Members of the genus Prototheca are the most common algae that leads to algaemia. Prototheca and Chlorella, which is extremely rare, are the only two known algae genera capable of inflicting disease on mammals, including humans, through invasion of host tissue. The majority of cases are observed in dairy cattle as a cause of bovine mastitis as well as other domesticated animals. Cases of algaemia have been observed in dogs and cats as well. Few cases have been observed in humans. Human cases of protothecosis are examined on a case-by-case basis due to the particularity of each case. Protothecosis infection is classified based on the symptoms: (i) cutaneous lesions, (ii) olecranon bursitis, and (iii) disseminated or systemic type infections.

Chlorellosis is a disease caused by the infection of Chlorella, a type of microalgae containing large amount of chloroplasts. It is mainly found in sheep and cattle, while cases in humans, dogs, antelopes, beavers, camels and fish, were also reported. Symptoms of Chlorellosis including focal cutaneous lesions, lymphadenitis, and peritonitis.

Asterochloris is a genus of green algae in the family Trebouxiophyceae. It is a common photobiont in lichen, occurring in the thalli of more than 20 lichen genera worldwide. Asterochloris is distinguishable from the morphologically similar genus Trebouxia, primarily due to its deeply lobed chloroplast, the placement of the chloroplast along the cell's periphery before the initiation of zoospore or aplanospore formation, and its tendency to primarily reproduce asexually through the production of aplanospores.

References

  1. Krüger, W. (1894). Kurze Charakteristik einiger niedrerer Organismen im Saftfluss der Laubbäume. Hedwigia 33: 241-266, .
  2. Jagielskia T, Bakułaa Z, Gaworb J, Maciszewskic K, Kusberd W, Dyląge M, Nowakowskaf J, Gromadkab R, Karnkowskac A (2019). "The genus Prototheca (Trebouxiophyceae, Chlorophyta) revisited: Implications from molecular taxonomic studies". Algal Research. 43. Bibcode:2019AlgRe..4301639J. doi:10.1016/j.algal.2019.101639.
  3. See the NCBI webpage on Prototheca. Data extracted from the "NCBI taxonomy resources". National Center for Biotechnology Information . Retrieved 2007-03-19.
  4. Ollhoff, Rüdiger D.; Sellera, Fábio P.; Pogliani, Fabio C. (November 2021). "Early Release -Etymologia: Prototheca". Emerg Infect Dis. 27 (11): 2891. doi: 10.3201/eid2711.211554 . PMC   8544978 . Citing public domain text from the CDC.
  5. Bicudo, Carlos E. M.; Menezes, Mariângela (2006). Gêneros de Algas de Águas Continentais do Brasil: chave para identificação e descrições (2 ed.). RiMa Editora. p. 508. ISBN   857656064X.
  6. Lass-Flörl, Cornelia; Mayr, Astrid (2007-04-01). "Human Protothecosis". Clinical Microbiology Reviews. 20 (2): 230–242. doi:10.1128/CMR.00032-06. ISSN   0893-8512. PMC   1865593 . PMID   17428884.
  7. Ueno, Ryohei; Urano, Naoto; Suzuki, Motofumi (2003-06-01). "Phylogeny of the non-photosynthetic green micro-algal genus Prototheca (Trebouxiophyceae, Chlorophyta) and related taxa inferred from SSU and LSU ribosomal DNA partial sequence data". FEMS Microbiology Letters. 223 (2): 275–280. doi:10.1016/s0378-1097(03)00394-x. ISSN   0378-1097. PMID   12829298.
  8. Plieger, Tanja; Wolf, Matthias (2022-02-01). "18S and ITS2 rDNA sequence-structure phylogeny of Prototheca (Chlorophyta, Trebouxiophyceae)". Biologia. 77 (2): 569–582. Bibcode:2022Biolg..77..569P. doi: 10.1007/s11756-021-00971-y . ISSN   1336-9563.
  9. Shave, Christopher D.; Millyard, Linda; May, Robin C. (2021). "Now for something completely different: Prototheca, pathogenic algae". PLOS Pathogens. 17 (4): e1009362. doi: 10.1371/journal.ppat.1009362 . PMC   8016101 . PMID   33793666.