Phantom cats, also known as Alien Big Cats (ABCs), are large felids, such as jaguars, cougars, and leopards, which allegedly appear in regions outside their indigenous range. Sightings, tracks and predation have been reported in a number of countries and states including Canada, Britain, Australia, Germany, France, Spain, Switzerland, Ireland, New Zealand, Finland, Denmark, the United States, Hawaii, Italy and Luxembourg.
Toxoplasmosis is a parasitic disease caused by Toxoplasma gondii, an apicomplexan. Infections with toxoplasmosis usually cause no obvious symptoms in adults. Occasionally, people may have a few weeks or months of mild, flu-like illness such as muscle aches and tender lymph nodes. In a small number of people, eye problems may develop. In those with a weak immune system, severe symptoms such as seizures and poor coordination may occur. If a woman becomes infected during pregnancy, a condition known as congenital toxoplasmosis may affect the child.
The cougar is a large cat of the subfamily Felinae. Native to the Americas, its range spans from the Canadian Yukon to the southern Andes in South America and is the most widespread of any large wild terrestrial mammal in the Western Hemisphere. It is an adaptable, generalist species, occurring in most American habitat types. Due to its wide range, it has many names including catamount, mountain lion, painter, panther and puma.
Nepetalactone is a name for multiple iridoid analog stereoisomers. Nepetalactones are produced by Nepeta cataria (catnip) and a many other plants belonging to the genus Nepeta, in which they protect these plants from herbivorous insects by functioning as insect repellents. They are also produced by many aphids, in which they are sex pheromones. Nepetalactones are cat attractants, and cause the behavioral effects that catnip induces in domestic cats. However, they affect visibly only about 2/3 of adult cats. They produce similar behavioral effects in many other Felidae, especially in lions and jaguars. McElvain and colleagues were the first to extract and name nepetalactones, which they did in 1941.
Simian immunodeficiency virus (SIV) is a species of retrovirus that cause persistent infections in at least 45 species of African non-human primates. Based on analysis of strains found in four species of monkeys from Bioko Island, which was isolated from the mainland by rising sea levels about 11,000 years ago, it has been concluded that SIV has been present in monkeys and apes for at least 32,000 years, and probably much longer.
Feline immunodeficiency virus (FIV) is a Lentivirus that affects cats worldwide, with 2.5% to 4.4% of felines being infected. FIV differs taxonomically from two other feline retroviruses, feline leukemia virus (FeLV) and feline foamy virus (FFV), and is more closely related to human immunodeficiency virus (HIV). Within FIV, five subtypes have been identified based on nucleotide sequence differences coding for the viral envelope (env) or polymerase (pol). FIV is the only non-primate lentivirus to cause an AIDS-like syndrome, but FIV is not typically fatal for cats, as they can live relatively healthily as carriers and transmitters of the disease for many years. A vaccine is available, although its efficacy remains uncertain. Cats will test positive for FIV antibodies after vaccination.
Toxocariasis is an illness of humans caused by larvae of either the dog roundworm, the cat roundworm or the fox roundworm. Toxocariasis is often called visceral larva migrans (VLM). Depending on geographic location, degree of eosinophilia, eye and/or pulmonary signs, the terms ocular larva migrans (OLM), Weingarten's disease, Frimodt-Møller's syndrome, and eosinophilic pseudoleukemia are applied to toxocariasis. Other terms sometimes or rarely used include nematode ophthalmitis, toxocaral disease, toxocarose, and covert toxocariasis. This zoonotic, helminthic infection is a rare cause of blindness and may provoke rheumatic, neurologic, or asthmatic symptoms. Humans normally become infected by ingestion of embryonated eggs from contaminated sources.
Feline leukemia virus (FeLV) is a retrovirus that infects cats. FeLV can be transmitted from infected cats when the transfer of saliva or nasal secretions is involved. If not defeated by the animal's immune system, the virus weakens the cat's immune system which can lead to diseases which can be lethal. Because FeLV is cat-to-cat contagious, FeLV+ cats should only live with other FeLV+ cats.
The Toxocaridae are a zoonotic family of parasitic nematodes that infect canids and felids and which cause toxocariasis in humans. The worms are unable to reproduce in humans.
Carnivore protoparvovirus 1 is a species of parvovirus that infects carnivorans. It causes a highly contagious disease in both dogs and cats. The disease is generally divided into two major genogroups: CPV-1 containing the classical feline panleukopenia virus (FPLV), and CPV-2 containing the canine parvovirus (CPV) which appeared in the 1970s.
Lentivirus is a genus of retroviruses that cause chronic and deadly diseases characterized by long incubation periods, in the human and other mammalian species. The best known lentivirus is the human immunodeficiency virus (HIV), which causes AIDS. Lentiviruses are also hosted in apes, cows, goats, horses, cats, and sheep. Recently, lentiviruses have been found in monkeys, lemurs, Malayan flying lemur, rabbits, and ferrets. Lentiviruses and their hosts have worldwide distribution. Lentiviruses can integrate a significant amount of viral cDNA into the DNA of the host cell and can efficiently infect nondividing cells, so they are one of the most efficient methods of gene delivery. Lentiviruses can become endogenous (ERV), integrating their genome into the host germline genome, so that the virus is henceforth inherited by the host's descendants.
Feline infectious peritonitis (FIP) is the name given to a common and aberrant immune response to infection with feline coronavirus (FCoV).
A felid hybrid is any of a number of hybrid between various species of the cat family, Felidae. This article deals with hybrids between the species of the subfamily Felinae.
Feline calicivirus (FCV) is a virus of the family Caliciviridae that causes disease in cats. It is one of the two important viral causes of respiratory infection in cats, the other being Felid alphaherpesvirus 1. FCV can be isolated from about 50% of cats with upper respiratory infections. Cheetahs are the other species of the family Felidae known to become infected naturally.
Viral vectors are tools commonly used by molecular biologists to deliver genetic material into cells. This process can be performed inside a living organism or in cell culture. Viruses have evolved specialized molecular mechanisms to efficiently transport their genomes inside the cells they infect. Delivery of genes or other genetic materia by a vector is termed transduction and the infected cells are described as transduced. Molecular biologists first harnessed this machinery in the 1970s. Paul Berg used a modified SV40 virus containing DNA from the bacteriophage λ to infect monkey kidney cells maintained in culture.
Visna virus from the genus Lentivirus and subfamily Orthoretrovirinae, is a "prototype" retrovirus that causes encephalitis and chronic pneumonitis in sheep. It is known as visna when found in the brain, and maedi when infecting the lungs. Lifelong, persistent infections in sheep occur in the lungs, lymph nodes, spleen, joints, central nervous system, and mammary glands; The condition is sometimes known as "ovine progressive pneumonia" (OPP), particularly in the United States, or "Montana sheep disease". White blood cells of the monocyte/macrophage lineage are the main target of visna virus.
Gene therapy using lentiviral vectors is being explored in early stage trials.
Janice Ellen Clements is Vice Dean for Faculty at the Johns Hopkins School of Medicine and the Mary Wallace Stanton Professor of Faculty Affairs. She is a professor in the departments of Molecular and Comparative Pathobiology, Neurology, and Pathology, and has a joint appointment in molecular biology and genetics. Her molecular biology and virology research examines lentiviruses and how they cause neurological diseases.
Many different species of mammal can be classified as cats (felids) in the United States. These include domestic cat, of the species Felis catus; medium-sized wild cats from the genus Lynx; and big cats from the genera Puma and Panthera. Domestic cats vastly outnumber wild cats in the United States.
