Pyrimidodiazepine synthase

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pyrimidodiazepine synthase
Identifiers
EC no. 1.5.4.1
CAS no. 93586-06-2
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In enzymology, a pyrimidodiazepine synthase (EC 1.5.4.1) is an enzyme that catalyzes the chemical reaction

a pyrimidodiazepine + glutathione disulfide + H2O 6-pyruvoyltetrahydropterin + 2 glutathione

The 3 substrates of this enzyme are pyrimidodiazepine, glutathione disulfide, and H2O, whereas its two products are 6-pyruvoyltetrahydropterin and glutathione.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with a disulfide as acceptor. The systematic name of this enzyme class is pyrimidodiazepine:glutathione-disulfide oxidoreductase (ring-opening, cyclizing). Other names in common use include PDA synthase, pyrimidodiazepine:oxidized-glutathione oxidoreductase (ring-opening,, and cyclizing). This enzyme participates in glutathione metabolism.

Related Research Articles

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References


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