R. Sowdhamini

Last updated

R. Sowdhamini
Born (1964-05-24) 24 May 1964 (age 59)
Tamil Nadu, India
Nationality Indian
Alma mater
Known forComputational studies on Protein Science
Awards
Scientific career
Fields
Institutions
Doctoral advisor

Ramanathan Sowdhamini (born 24 May 1964) is an Indian computational biologist, bioinformatician and a professor at the department of biochemistry, biophysics and bioinformatics of the National Centre for Biological Sciences, a TIFR research facility located in Bengaluru. Known for computational studies in the field of Protein Science, Sowdhamini is also associated with the Institute for Stem Cell Biology and Regenerative Medicine as a collaborator and is an elected fellow of the Indian Academy of Sciences as well as the Indian National Science Academy. The Department of Biotechnology of the Government of India awarded her the National Bioscience Award for Career Development, one of the highest Indian science awards, for her contributions to biosciences in 2007.

Contents

Biography

NCBS Campus NCBS Bangalore Campus.JPG
NCBS Campus

Born on 24 May 1964 [1] in the south Indian state of Tamil Nadu, Sowdhamini earned a post graduate degree from the Indian Institute of Technology, Madras in basic chemistry and enrolled at the Indian Institute of Science for her doctoral studies from where she secured a PhD. [2] Subsequently, she did her post-doctoral work in the UK, first at Birkbeck, University of London [note 1] and later, at the University of Cambridge. On her return to India, she joined the National Centre for Biological Sciences (NCBS), a research facility in Bengaluru, jointly funded by the Tata Institute of Fundamental Research and the Department of Atomic Energy as a member of faculty [3] where she serves as a professor at the department of biochemistry, biophysics and bioinformatics. [4] She also serves as a collaborator at the Centre for Cardiovascular Biology and Disease of the Institute for Stem Cell Biology and Regenerative Medicine (inStem) of the Department of Biotechnology. [5]

Legacy

Tulsi plant Starr 080117-1577 Ocimum tenuiflorum.jpg
Tulsi plant

Sowdhamini's research is in the fields of computational studies of Protein Science as well as genome sequencing and she is reported to have done advanced research in the code development for studying Protein folding and unfolding. [6] She leads a group of scientists engaged in the computational studies of proteins with regard to their random rearrangements during evolution [7] and they have carried out genome surveys of several protein families and superfamilies. [8] Her team was successful in preparing the draft genome of Ocimum tenuiflorum (commonly known as Tulsi), a plant with medicinal properties, for the first time which assisted in identifying the genes responsible for the production of Ursolic acid, a triterpenoid and Eugenol, a phenylpropanoid, compounds responsible for the medicinal properties of the plant. [9] [10] She was the lead developer of 3DSwap, a database of 3D domain-swapped proteins. [11] Besides, along with James Spudich of the Stanford University and Henrik Flyvbjerg of the Technical University of Denmark, she led the project for studying coiled coil interactions in proteins, a collaborative project of the two institutions and the National Centre for Biological Sciences. [12] Her studies have been documented by way of a number of articles [13] [note 2] and ResearchGate, an online repository of scientific articles has listed 427 of them. [14] She sits in the editorial board of Bioinformation journal [15] and has also mentored many post-graduate, doctoral ad post-doctoral scholars in their research. [16] [17] [18]

Awards and honours

The Department of Biotechnology of the Government of India awarded Sowdhamini the National Bioscience Award for Career Development, one of the highest Indian science awards in 2007. [19] She was elected as a fellow by the Indian Academy of Sciences in 2010 [20] and she received the Human Frontier Science Program Award the same year. [21] A year later, The Indian National Science Academy elected her as a fellow in 2011. [22] She is also a recipient of the Bharat Jyoti Award of the India International Friendship Society. [23] She is a J. C. Bose National Fellow of the Department of Science and Technology since 2016.

Selected bibliography

See also

Notes

  1. Under the guidance of Tom Blundell, a Knight Bachelor
  2. Please see Selected bibliography section

Related Research Articles

<span class="mw-page-title-main">Jayant B. Udgaonkar</span> Indian biochemist, molecular biologist (born 1960)

Jayant Bhalchandra Udgaonkar is an Indian biochemist, molecular biologist, and academic at the Indian Institute of Science Education and Research, Pune. He is the former Director of the Indian Institute of Science Education and Research, Pune, and was previously a senior professor at the National Centre for Biological Sciences. A J.C. Bose National Fellow, he is known for his studies on protein folding. He is an elected fellow of the Indian Academy of Sciences, Indian National Science Academy and The World Academy of Sciences. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2000, for his contributions to biological sciences. He is the son of noted scientist Padmabhushan Bhalchandra Udgaonkar.

Umesh Varshney is an Indian molecular biologist, academician and the head of a laboratory at the Indian Institute of Science, Bengaluru. He is a J. C. Bose National Fellow of the Department of Science and Technology and is known for his studies on protein synthesis and DNA repair in Escherichia coli and Mycobacterium tuberculosis. An elected fellow of the Indian Academy of Sciences, Indian National Science Academy and the National Academy of Sciences (India), he is also a recipient of the National Bioscience Award for Career Development of the Government of India. The Council of Scientific and Industrial Research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2001, and then in 2014 with the G. N. Ramachandran Gold Medal for Excellence in Biological Sciences & Technology for his contributions to biological sciences.

Narayanaswamy Srinivasan was an Indian molecular biophysicist and a professor and the head of Proteins: Structure, Function and Evolutionary Group at the Molecular Biophysics Unit of the Indian Institute of Science. He is known for his researches in the fields of computational genomics and protein structure analysis. An elected fellow of the Indian Academy of Sciences and the National Academy of Sciences, India, he is a J. C. Bose National fellow of the Department of Biotechnology and a recipient of the National Bioscience Award for Career Development of the Department of Science and Technology. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2007, for his contributions to biological sciences.

<span class="mw-page-title-main">L. S. Shashidhara</span>

Lingadahalli Subrahmanya Shashidhara is an Indian developmental biologist, geneticist and a professor of biology currently serving as the Centre Director of National Centre for Biological Sciences, Bengaluru, India. He is a Professor at the Indian Institute of Science Education and Research, Pune, and at Ashoka University, Sonepat, India. He heads the LSS Laboratory at IISER and is known for his studies on Drosophila, particularly the evolution of appendages and functions of homeotic selector genes. He is a J. C. Bose National Fellow of the Department of Science and Technology and an elected fellow of the Indian National Science Academy, Indian Academy of Sciences and the National Academy of Sciences, India. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2008, for his contributions to biological sciences.

Sanjeev Anant Galande is an Indian cell biologist, epigeneticist, academic, former Chair of Biology and the Dean of Research and Development at the Indian Institute of Science Education and Research, Pune. He heads the Laboratory of Chromatin Biology and Epigenetics at the Indian Institute of Science Education and Research, Pune. He is the founder of the Centre of Excellence in Epigenetics at IISER Pune and is known for his studies on higher-order chromatin architecture and how it influences spatiotemporal changes in gene expression. He is an elected fellow of the Indian National Science Academy and the Indian Academy of Sciences and a recipient of the National Bioscience Award for Career Development of the Department of Biotechnology. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2010, for his contributions to biological sciences.

Akhilesh Kumar Tyagi is an Indian plant biologist and the former director of National Institute of Plant Genome Research. Known for his studies on plant genomics and biotechnology, Tyagi is an elected fellow of all the three major Indian science academies namely Indian Academy of Sciences, Indian National Science Academy and National Academy of Sciences, India as well as The World Academy of Sciences and the National Academy of Agricultural Sciences. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences in 1999.

Anil Grover is an Indian molecular biologist, professor and the head of the Department of Plant Molecular Biology at the University of Delhi. He also heads the Anil Grover Lab of the department, serving as the principal investigator. Known for his research in the field of molecular biology of plants, Grover is an elected fellow of all the three major Indian science academies namely the National Academy of Sciences, India, the Indian Academy of Sciences and the Indian National Science Academy as well as the National Academy of Agricultural Sciences. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences in 2002.

Kanakaraj Sekar is an Indian bioinformatician and a professor at the Department of Computational and Data Sciences of the Indian Institute of Science (IISc). Known for his studies in the field of bioinformatics, Sekar heads the Laboratory for Structural Biology and Bio-computing at IISc. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences in 2004.

Apurva Sarin is an Indian cell biologist and is presently Sr. Professor and Director of Institute for Stem Cell Science and Regenerative Medicine (inStem), an Autonomous Institution under Department of Biotechnology, Govt. of India. Formerly, she was a professor at the National Centre for Biological Sciences. Known for her studies on the Mechanisms of apoptosis in metazoan cells, Sarin also serves as the dean of research at the Institute for Stem Cell Biology and Regenerative Medicine (inStem) and is an elected fellow of the Indian Academy of Sciences. An alumnus of the University of Delhi, she did her doctoral studies at the Jawaharlal Nehru University and the post-doctoral work at the National Cancer Institute of the National Institutes of Health. Her studies have been documented by way of a number of articles and the online article repository of the Indian Academy of Sciences has listed 44 of them. The Department of Biotechnology of the Government of India awarded her the National Bioscience Award for Career Development, one of the highest Indian science awards, for her contributions to biosciences in 2005.

Saumitra Das is an Indian microbiologist and a professor at the Department of Microbiology and Cell Biology of the Indian Institute of Science. Known for his studies in the fields of molecular virology and molecular biology, Das is an elected fellow of all the three major Indian science academies namely, the Indian Academy of Sciences, the National Academy of Sciences, India and the Indian National Science Academy. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences in 2005.

Kumaravel Somasundaram is an Indian cancer biologist and a professor at the Department of Microbiology and Cell Biology of the Indian Institute of Science. Known for his studies on the therapeutics of Glioblastoma, Somasunderam is an elected fellow of all the three major Indian science academies namely, the National Academy of Sciences, India, the Indian Academy of Sciences and the Indian National Science Academy. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences in 2006.

Snehasikta Swarnakar is an Indian chemical biologist and the senior principal scientist at the Division of Cancer Biology and Inflammatory Disorder of the Indian Institute of Chemical Biology. Known for her studies in the field of gastric, ovarian, head and neck cancers, Swarnakar is an elected fellow of the National Academy of Sciences, India and the West Bengal Academy of Science and Technology. The Department of Biotechnology of the Government of India awarded her the National Bioscience Award for Career Development, one of the highest Indian science awards, for her contributions to biosciences in 2007.

Nihar Ranjan Jana is an Indian neuroscientist and professor at the IIT Kharagpur, known for his studies on E3 ubiquitin ligases, protein homeostasis and neurodegenerative disorders. Jana is an elected fellow of the National Academy of Sciences, India. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, in 2008 and TATA Innovation Fellowship in 2014 for his contributions to Neurodegenerative diseases.

Ramasubbu Sankararamakrishnan is an Indian computational biologist, bioinformatician and a professor at the Department of Biological Sciences and Bioengineering of the Indian Institute of Technology, Kanpur. He is known for his computational studies on membrane protein function. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences in 2008.

Nagasuma Chandra is an Indian structural biologist, biochemist and a professor at the department of biochemistry of the Indian Institute of Science. She is known for her studies on Mycobacterium tuberculosis. The Department of Biotechnology of the Government of India awarded her the National Bioscience Award for Career Development, one of the highest Indian science awards, for her contributions to biosciences in 2008.

Balaji Prakash is an Indian structural biologist, biochemist and the Associate Dean of Sciences & Professor, Biological and Life Sciences, at the School of Arts and Sciences, Ahmedabad University, since July 2020. Prior to this he served as senior principal scientist and the head of the department of molecular nutrition of the Central Food Technological Research Institute. Known for elucidating the structure of a unique GTP-binding protein, Prakash is an elected fellow of the National Academy of Sciences, India and was a senior research fellow of The Wellcome Trust, UK. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2009.

Debasisa Mohanty is an Indian computational biologist, bioinformatician and a staff scientists at the National Institute of Immunology, India. Known for his studies on structure and function prediction of proteins, genome analysis and computer simulation of biomolecular systems, Mohanty is an elected fellow of all the three major Indian science academies namely the Indian Academy of Sciences, the Indian National Science Academy and the National Academy of Sciences, India. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2009.

Alok Krishna Sinha is an Indian molecular biologist, biochemist, plant physiologist and a staff scientist Grade VII at the National Institute of Plant Genome Research (NIPGR). Known for his research on Mitogen-activated protein kinase (MAPK) cascade in plants, he is a three-time Alexander von Humboldt Fellow and an elected fellow of the National Academy of Sciences, India. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2013.

Arun Kumar Shukla is an Indian structural biologist and the Joy-Gill Chair professor at the department of biological sciences and bioengineering at the Indian Institute of Technology, Kanpur. Known for his studies on G protein-coupled receptor, Shukla is a Wellcome Trust-DBT Intermediate Fellow and a recipient of the SwarnaJayanti Fellowship of the Department of Science and Technology. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2017/18. He received the 2021 Shanti Swarup Bhatnagar Prize for Science and Technology in Biological Science. He was awarded the Infosys Prize 2023 in Life Sciences his outstanding contributions to the biology of G-protein coupled receptors (GPCRs).

Ranjith Padinhateeri is an Indian biological physicist and a professor at the Indian Institute of Technology, Mumbai. He is known for his biological studies using statistical mechanics, polymer physics, and soft matter theory. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2017–18.

References

  1. "Fellow profile". Indian Academy of Sciences. 26 December 2017. Retrieved 26 December 2017.
  2. "Speaker: R. Sowdhamini – Bioinformatica Indica 2016". BioIndica – Google. 26 December 2017. Retrieved 26 December 2017.[ permanent dead link ]
  3. "Indian fellow". Indian National Science Academy. 21 December 2017. Archived from the original on 23 December 2017. Retrieved 21 December 2017.
  4. "Faculty – NCBS". National Centre for Biological Sciences. 26 December 2017. Retrieved 26 December 2017.
  5. "Faculty – InStem". Institute for Stem Cell Biology and Regenerative Medicine. 26 December 2017. Retrieved 26 December 2017.
  6. Phillip R. Westmoreland; Peter A. Kollman; Anne M. Chaka, Peter T. Cummings, Keiji Morokuma, Matthew Neurock, Ellen B. Stechel, Priya Vashishta (17 April 2013). Applying Molecular and Materials Modeling. Springer Science & Business Media. pp. 184–. ISBN   978-94-017-0765-7.{{cite book}}: CS1 maint: multiple names: authors list (link)
  7. "Lab Members – NCBS". ncbs.res.in. 26 December 2017. Retrieved 26 December 2017.
  8. "Prof. R. Sowdhamini – NCBS". National Centre for Biological Sciences. 26 December 2017. Retrieved 26 December 2017.
  9. "Scientists decode humble tulsi". The Times of India. 10 September 2015. Retrieved 26 December 2017.
  10. Prasad, R. (30 August 2015). "Medicinal properties of tulsi unravelled". The Hindu. ISSN   0971-751X . Retrieved 26 December 2017.
  11. "Swapping long-drawn data searches for ingenuity: 3DSwap". NCBS news. 13 March 2012. Retrieved 26 December 2017.
  12. "VLife to develop Advanced Technology for NCBS, Bengaluru, Stanford University and Technical University of Denmark". Business Wire India. 25 March 2010. Retrieved 26 December 2017.
  13. "Browse by Fellow". Indian Academy of Sciences. 26 December 2017. Retrieved 26 December 2017.
  14. "On ResearchGate". 21 December 2017. Retrieved 21 December 2017.
  15. "Editorial Board Bioinformation". bioinformation.net. 26 December 2017. Retrieved 26 December 2017.
  16. "Nitish Sathyanarayanan NCBS". ncbs.res.in. 26 December 2017. Retrieved 26 December 2017.
  17. "Shaik Naseer Pasha NCBS". ncbs.res.in. 26 December 2017. Retrieved 26 December 2017.
  18. "Oommen K. Mathew NCBS". ncbs.res.in. 26 December 2017. Retrieved 26 December 2017.
  19. "Awardees of National Bioscience Awards for Career Development" (PDF). Department of Biotechnology. 2016. Archived from the original (PDF) on 4 March 2018. Retrieved 20 November 2017.
  20. "Fellowship – Indian Academy of Sciences". ias.ac.in. 21 December 2017. Retrieved 21 December 2017.
  21. "Prof. R. Sowdhamini: HFSP Awardee – NCBS news". news.ncbs.res.in. 23 April 2011. Retrieved 26 December 2017.
  22. "INSA Year Book 2016" (PDF). Indian National Science Academy. 26 December 2017. Retrieved 26 December 2017.
  23. "Prof. R. Sowdhamini – News – NCBS". ncbs.res.in. Retrieved 26 December 2017.

Further reading