Sudhanshu Vrati

Last updated

Sudhanshu Vrati
Born (1960-03-19) 19 March 1960 (age 64)
Uttar Pradesh, India
Nationality Indian
Alma mater
Known forStudies in RNA virus replication and vaccine development
Awards
Scientific career
Fields
Institutions

Sudhanshu Vrati (born 19 March 1960) is an Indian immunologist, microbiologist and the director of the Regional Centre for Biotechnology. Known for his studies in the fields of RNA virus replication and vaccine development, Vrati is an elected fellow of the National Academy of Sciences, India, Indian National Science Academy and the Indian Academy of Sciences. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences in 2003. [1]

Contents

Biography

G. B. Pant University of Agriculture and Technology - Office of the vice chancellor VC Office building Pantnagar.JPG
G. B. Pant University of Agriculture and Technology - Office of the vice chancellor
Making of a DNA vaccine Making of a DNA vaccine.jpg
Making of a DNA vaccine

Born on 19 March 1960 in the Indian state of Uttar Pradesh, [2] Sudhanshu Vrati earned an MSc in microbiology from G. B. Pant University of Agriculture and Technology and did a DIIT in biochemical engineering at the Indian Institute of Technology, Delhi. [3] Subsequently, he moved to Australia for his doctoral studies and secured a PhD in biochemistry from the Australian National University. His post-doctoral work was at the Commonwealth Scientific and Industrial Research Organisation (CSIRO) center in Sydney and on his return to India, he joined the National Institute of Immunology as a scientist. [4] He was working as a senior scientist when he was appointed as the dean at the Translational Health Science and Technology Institute (THSTI) in 2005. [5] In October 2015, he was transferred, on deputation, to the Regional Centre for Biotechnology (RCB) as its executive director, a post he held till May 2023. [3] He is also a visiting scientist at the Pasteur Institute, Paris and an executive director of Bharat Immunologicals and Biologicals Corporation, [6] a Government of India undertaking involved in the manufacture of vaccines and immunizers. [7]

Legacy

Vrati's early researches at THSTI focused on JEV life-cycle like receptor binding and entry mechanisms, molecular mechanisms of virus replication, assembly, egress as well as the clinical development of an oral rotavirus vaccine. Later, he concentrated on the development of DNA vaccines and the details of the work has since been published as an article, DNA vaccines: Getting closer to becoming a reality, in 2013. [8] His work on rat brains help identify Mov34 protein which has assisted in the development of vaccines for flaviviral diseases like Japanese encephalitis and Dengue. [9] His studies have been documented by way of a number of articles. [10] [11] [note 1] Besides, he has contributed chapters to books edited by others. [12] [13] He holds several patents for the process he has developed. [14] [15] [16]

Awards and honors

It was during his days at the National Institute of Immunology, Vrati received the 2001 VASVIK Industrial Research Award. [17] The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards in 2003; [1] the elected membership of the Guha Research Conference reached him the same year. [3] He was elected as a fellow by the National Academy of Sciences, India in 2004; [18] the same year as he received the elected fellowship of the Indian Academy of Sciences. [19] The Indian National Science Academy selected him for the Professor KP Bhargava Memorial Medal [20] and the Association of Microbiologists of India chose him for the Alembic Award, both in 2005. [21] The National Academy of Sciences, India honored him again in 2006 with the NASI-Reliance Platinum Jubilee Award. [22] He received the Tata Innovation Fellowship of the Department of Biotechnology in 2009 and the High Commission of Australia in India awarded him the Australian Alumni Award in 2010 [23] The award orations delivered by him include the 2003 edition of the Dr. J. B. Srivastava Oration of the Indian Council of Medical Research. [24] In 2021, he was conferred the prestigious J C Bose National Fellowship of SERB.

Selected bibliography

Chapters

Articles

See also

Notes

  1. Please see Selected bibliography section

Related Research Articles

Translational Health Science and Technology Institute (THSTI) is an institute of the Biotechnology Research and Innovation Council (BRIC), Department of Biotechnology, Ministry of Science and Technology, Government of India. It was set up in 2009 and is located in NCR Biotech Science Cluster, Faridabad. Envisioned by former secretary of DBT, Dr. M. K. Bhan, the institute was created to enable a faster transition of lab research to market. Prof. Ganesan Karthikeyan is the Executive Director of THSTI.

Virander Singh Chauhan is an Indian scientist and a Rhodes Scholar working in the fields of genetic engineering and biotechnology. He is known for his contributions to the development of a recombinant vaccine for malaria. and for synthetic structural peptides with biological functions. He was honored by the Government of India in 2012 with the fourth highest Indian civilian award of Padma Shri. He is the present Chancellor of the Gandhi Institute of Technology and Management.

Kanury Raoalso known as Kanury Venkata Subba Rao is an Indian immunologist. He was the head of the Drug Discovery Research Centre (DDRC) at the Translational Health Science and Technology Institute (THSTI) Faridabad. He is known for his studies in the fields of peptide synthesis and cell signaling and the design of synthetic peptide vaccines. He is an elected fellow of the Indian Academy of Sciences, National Academy of Sciences, India and the Indian National Science Academy. and a recipient of several awards including the Millennium Plaque of Honour of the Indian Science Congress and the National Bioscience Award for Career Development. The Council of Scientific and Industrial Research awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, in 1997, for his contributions to biological sciences.

<span class="mw-page-title-main">Rajesh Sudhir Gokhale</span> Indian chemical biologist (born 1967)

Rajesh Sudhir Gokhale is a Professor of Biology at Indian Institute of Science Education and Research, Pune on lien. Currently, serving as Secretary for Department of Biotechnology (DBT) Government of India from October 2021 onwards. He joined as a faculty in National Institute of Immunology, India after conducting his postdoctoral training at Stanford University, He was the Director of Institute of Genomics and Integrative Biology from 2009 to 2016. Gokhale is known for his studies on the metabolic diversity of pathogens. He is credited with the discovery of a family of Long-chain Fatty acyl-AMP ligases (FAAL) and his studies assisted in the elucidation of biochemical crosstalk between fatty acid synthases and polyketide synthases in Mycobacterium tuberculosis. He holds US and Indian patents for his invention of Method to Modulate Pigmentation Process in the Melanocytes of Skin. An alumnus of the Indian Institute of Science, he is an elected fellow of the Indian Academy of Sciences (2007) and the Indian National Science Academy (2014). The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2006, for his contributions to biological sciences. He received the National Bioscience Award for Career Development of the Department of Biotechnology in 2009.

Suman Kumar Dhar is an Indian molecular biologist and a professor at the Special Centre for Molecular Medicine of Jawaharlal Nehru University. He is known for his studies on the DNA replication and cell cycle regulation in Helicobacter pylori and Plasmodium falciparum, two pathogens affecting humans. An elected fellow of the National Academy of Sciences, India, Indian National Science Academy and the Indian Academy of Sciences, he is also a recipient of the National Bioscience Award for Career Development of the Department of Biotechnology in 2010. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2012, for his contributions to biological sciences.

<span class="mw-page-title-main">Shahid Jameel</span> Indian virologist and academic (born 1957)

Shahid Jameel is an Indian virologist and academic. Dr. Jameel is the Sultan Qaboos bin Said Fellow at Oxford Centre for Islamic Studies and Research Fellow, Green Templeton College, University of Oxford. He serves as the Principal Investigator for the Centre's project on Public Health, Science and Technology in Muslim societies. Previously he was the director of the Trivedi School of Biosciences since its inception in the year 2020 at Ashoka University. He was formerly head of the scientific advisory group to the Indian SARS-CoV-2 Genomics Consortia (INSACOG) established in December 2020, and the chief executive officer of Wellcome Trust DBT India Alliance. Known for his research in hepatitis E virus, Jameel is an elected fellow of all the three major Indian science academies viz. National Academy of Sciences, India, Indian Academy of Sciences, and Indian National Science Academy. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards for his contributions to Medical Sciences in 2000.

Javed Naim Agrewala is an Indian immunologist, the prof. at Indian Institute of Technology Ropar and the chief scientist and professor at the Institute of Microbial Technology, Chandigarh. Known for his research on Tuberculosis, Agrewala is an elected fellow of all the three major Indian science academies viz. National Academy of Sciences, India, Indian National Science Academy and Indian Academy of Sciences. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards for his contributions to Medical Sciences in 2005. He is also a recipient of the National Bioscience Award for Career Development of the Department of Biotechnology.

Pundi Narasimhan Rangarajan is an Indian biochemist, virologist and a professor at the department of biochemistry of the Indian Institute of Science. Prof Rangarajan is currently the Chairman of the Department of Biochemistry at Indian Institute of Science. Known for his research on eukaryotic gene expression, Rangarajan is an elected fellow of all the three major Indian science academies viz. National Academy of Sciences, India, Indian Academy of Sciences and Indian National Science Academy. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards for his contributions to Medical Sciences in 2007.

<span class="mw-page-title-main">M. Radhakrishna Pillai (scientist)</span> Indian cancer biologist

Madhavan Radhakrishna Pillai is an Indian cancer biologist and the former director of the Rajiv Gandhi Centre for Biotechnology. Known for his studies on papilloma viruses, Pillai is an elected fellow of the Indian Academy of Sciences, National Academy of Sciences, India, Royal College of Pathologists and the National Academy of Medical Sciences. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences in 2002.

Rajendra Prasad Roy is an Indian chemical biologist, biochemist and a scientist at the National Institute of Immunology. Known for his studies in protein engineering, Roy has developed several chemo-enzymatic strategic processes for which he has a patent assigned to him. He holds a PhD from the Indian Institute of Science and is an elected fellow of all the three major Indian science academies namely Indian National Science Academy, Indian Academy of Sciences, and National Academy of Sciences, India. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for him contributions to biosciences in 2005. Currently he is the dean of Regional Centre for Biotechnology, Faridabad.

Dulal Panda is an Indian cell biologist and the chair professor at the department of biosciences and bioengineering of the Indian Institute of Technology, Bombay. Presently, he is the Director of NIPER, SAS Nagar (Mohali). Known for his studies on microtubule dynamics and FtsZ assembly dynamics, Panda is an elected fellow of the Indian Academy of Sciences and the National Academy of Sciences, India. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences in 2005.

Saumitra Das is an Indian microbiologist and a professor at the Department of Microbiology and Cell Biology of the Indian Institute of Science. Known for his studies in the fields of molecular virology and molecular biology, Das is an elected fellow of all the three major Indian science academies namely, the Indian Academy of Sciences, the National Academy of Sciences, India and the Indian National Science Academy. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences in 2005.

Tilak Raj Sharma is an Indian plant biologist, the Deputy Director General (CS) of ICAR and former executive director and chief executive officer of the National Agri-Food Biotechnology Institute (NABI), and Center of Innovative and Applied Bioprocessing (CIAB) respectively, both autonomous institutes under the Department of Biotechnology. Known for his studies in the fields of genomics and plant disease resistance, Sharma is an elected fellow of the National Academy of Sciences, India, the National Academy of Agricultural Sciences and the Indian National Science Academy. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences in 2007.

Gopal Dhinakar Raj is an Indian veterinary scientist, an academic and the project director of the Translational Research Platform for Veterinary Biologicals, a partnership program between the Department of Biotechnology and the Tamil Nadu Veterinary and Animal Sciences University. Known for the development of diagnostic test kits for animal and poultry diseases such as Leptospirosis and Egg drop syndrome, Raj is a member of the DBT Task Force on Animal Biotechnology. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences in 2007.

Anirban Basu is an Indian neurobiologist, who is primarily interested in neurovirology, a senior scientist at the National Brain Research Centre, a deemed to be university, located in Manesar, Gurgaon, Haryana. He is internationally known for his studies on Japanese encephalitis. Basu is an elected fellow of all the three major Indian science Academies namely the Indian Academy of Sciences, the Indian National Science Academy and the National Academy of Sciences, India as well as of the West Bengal Academy of Science and Technology. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the prominent Indian science awards, for his contributions to biosciences and biotechnology, in 2010.

Santasabuj Das is an Indian medical doctor, molecular immunologist, bioinformatician and a scientist at the National Institute of Cholera and Enteric Diseases, Kolkata. He is known for his studies on the pathogenesis of various types of infections caused by Salmonella in humans and is an elected fellow of the West Bengal Academy of Science and Technology. He is a former Fulbright scholar and a life member of the Probiotic Association of India, the Society of Biological Chemists, India and the Indian Science Congress Association. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2011.

Dr. Manmohan Parida, Sc ‘H’ is the director of the Indian Defence Research and Development Establishment (DRDE) in Gwalior. He assumed the position with effect from 1 October 2021. He obtained his graduation in Veterinary Science from Odisha Veterinary College as best graduate with three Gold Medals into his credit. He earned his master's degree in Veterinary Virology from prestigious Indian Veterinary Research Institute, Mukteswar and further obtained his Doctorate Jiwaji University, Gwalior in Microbiology. He was also awarded with Monbusho Fellowship from Japanese Govt and pursued Post Doctoral Research Scientist at Institute of Tropical Medicine, WHO reference center for research on arboviruses, Nagasaki, Japan.

Naval Kishore Vikram is an Indian physician, diabetologist and a professor at the department of medicine of the All India Institute of Medical Sciences, Delhi. He is known for his studies in the field of metabolic disorders with special emphasis on insulin resistance and obesity and his work assisted in profiling the Indian population with regard to imbalanced dietary practices and cardiovascular risk factors. He was a member of the group which proposed guidelines for obesity management, metabolic syndrome, and dietary controls for Asian Indians. His studies have been documented by way of a number of articles and ResearchGate, an online repository of scientific articles has listed 125 of them.

Ramandeep Singh is an Indian molecular biologist, geneticist and a professor at the Translational Health Science and Technology Institute. Known for his studies on the pathogenesis of Mycobacterium tuberculosis, he is a former research fellow of the National Institutes of Health. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2014.

<span class="mw-page-title-main">Bharat Biotech</span> Indian multinational biotechnology company and vaccine manufacturer

Bharat Biotech International Limited (BBIL) is an Indian multinational biotechnology company based in Hyderabad, which is engaged in drug discovery, drug development, and the manufacture of vaccines, biotherapeutics, pharmaceuticals and healthcare products.

References

  1. 1 2 "Awardees of National Bioscience Awards for Career Development" (PDF). Department of Biotechnology. 2016. Archived from the original (PDF) on 4 March 2018. Retrieved 20 November 2017.
  2. "Fellow profile". Indian Academy of Sciences. 12 November 2017. Retrieved 12 November 2017.
  3. 1 2 3 "Vrati on THSTI" (PDF). Translational Health Science and Technology Institute. 12 December 2017. Retrieved 12 December 2017.
  4. "Director profile". Regional Centre for Biotechnology. 12 December 2017. Retrieved 12 December 2017.
  5. Desk, BioVoice News (15 October 2016). "Prof Sudhanshu Vrati takes charge as Executive Director at RCB, Faridabad". BioVoiceNews. Retrieved 12 December 2017.{{cite news}}: |last= has generic name (help)
  6. 4-traders. "Sudhanshu Vrati, PhD - Biography". www.4-traders.com. Retrieved 12 December 2017.{{cite web}}: CS1 maint: numeric names: authors list (link)
  7. "About BIBCOL – National Institute of Solar Energy". www.bibcol.com. 12 December 2017. Retrieved 12 December 2017.
  8. Kaushik Bharati, Sudhanshu Vrati (2013). "DNA vaccines: Getting closer to becoming a reality". Indian J Med Res. 137 (6): 1027–8. PMC   3734707 . PMID   23852283.
  9. Gregory R. Bock; Jamie A. Goode (2 October 2006). New Treatment Strategies for Dengue and Other Flaviviral Diseases. John Wiley & Sons. pp. 147–. ISBN   978-0-470-05801-5.
  10. "Browse by Fellow". Indian Academy of Sciences. 6 December 2017. Retrieved 6 December 2017.
  11. "On Google Scholar". Google Scholar. 23 November 2017. Retrieved 23 November 2017.
  12. Malik Zainul Abdin; Usha Kiran; Kamaluddin, Athar Ali (10 March 2017). Plant Biotechnology: Principles and Applications. Springer. pp. 329–. ISBN   978-981-10-2961-5.
  13. Ta, M.; Vrati, S. (June 2000). "Mov34 protein from mouse brain interacts with the 3' noncoding region of Japanese encephalitis virus". Journal of Virology. 74 (11): 5108–5115. doi:10.1128/jvi.74.11.5108-5115.2000. ISSN   0022-538X. PMC   110863 . PMID   10799585.
  14. "Sudhanshu VRATI Inventions, Patents and Patent Applications". patents.justia.com. 12 December 2017. Retrieved 12 December 2017.
  15. "Novel japanese encephalitis vaccine and method of manufacturing the same". Google Patents. 12 December 2017. Retrieved 12 December 2017.
  16. "Dna encoding ovine adenovirus (oav287) and its use as a viral vector". Google Patents. 12 December 2017. Retrieved 12 December 2017.
  17. "Biological Sciences & Technology". www.vasvik.org. 12 December 2017. Archived from the original on 14 June 2021. Retrieved 12 December 2017.
  18. "NASI Year Book 2015" (PDF). National Academy of Sciences, India. 24 November 2017. Archived from the original (PDF) on 6 August 2015. Retrieved 24 November 2017.
  19. "Fellowship - Indian Academy of Sciences". www.ias.ac.in. 12 December 2017. Retrieved 12 December 2017.
  20. "Professor KP Bhargava Memorial Medal". Indian National Science Academy. 12 December 2017. Retrieved 12 December 2017.
  21. "Alembic Award". Association of Microbiologists of India. 12 December 2017. Retrieved 12 December 2017.
  22. "NASI-Reliance Industries Platinum Jubilee Award". National Academy of Sciences, India. 12 December 2017. Retrieved 12 December 2017.
  23. "Australian Alumni Award" (PDF). National Institute of Immunology. 12 December 2017. Retrieved 12 December 2017.
  24. "ICMR Awards and Prizes" (PDF). Indian Council of Medical Research. 12 December 2017. Archived from the original (PDF) on 4 March 2016. Retrieved 12 December 2017.

Further reading