S. culicis was first described as Trypanosoma (Herpetomonas) culicis in 1907 by Frederick G. Novy, Ward J. MacNeal, and Harry N. Torreyin 1907.[7] The species name refers to the mosquito genus Culex in which it was found, although it has been found to also be present in other mosquitos such as Aedes.[8] Another description by F.G. Wallace and A. Johnson as Blastocrithidia culicis, published in 1961 based on specimens from Aedes vexans,[3] was later considered synonymous to Herpetomonas culicis. Eventually, by microbiological analysis of endosymbiont harboring Trypanosoma, this species was assigned to the genus Strigomonas in 2011, bearing the current name S. culicis.[2]
The obligate bacterium belongs a group of ß-proteobacterium and provides nutrients to the host, in addition to influencing some of the cellular functions.[9]
Biology
Stages of dividing Strigomonas culicis with its bacterial symbiont - S (blue in 2 picture) and green indicate the bacterium; K denotes the kinetoplast, and N, the nucleus
S. culicis spends its life cycle in mosquitos. It migrates from the mosquito midgut and enter the body cavity (haemocoel) and finally reside in the salivary glands.[10] Unlike other trypanosomatids, S. culicis does not produce some amino acids such as methionine, histidine, and arginine; and vitamins such as thiamin, nicotinamide, and riboflavin.[8] The bacterium provides these nutrients. In addition, it also provides enzymes required by the host for amino acid synthesis, lipid and purine/pyrimidine metabolism, urea cycle, haeme biosynthesis,[11]protein synthesis, and protein folding. It can not reproduce on its own and relies on signals from the protist's nucleus.[6] Isolated bacteria cannot survive on their own.[11] When the bacteria are removed by antibiotic treatment, the protist survives but can not infect mosquitos.[6]
The bacterium Ca. Kinetoplastibacterium blastocrithidii is a ß-proteobacterium of the family Alcaligenaceae. It is enclosed in two layers of cell membranes, and unlike typical bacterial membrane, peptidoglycan is greatly reduced.[11] It acts as a cell organelle not only by supplying essential enzymes, but also by replacing paraflagellar rod associated to the axoneme, thus, intimately associated with the kinetoplast.[12] In addition, it provides surplus supply of ATP molecules for increased metabolic activities.[13] During cell division, as the kinetoplast of the host divides so do the bacterium.[14] The host cell controls the number of bacterial division.[1] This coordinated mitosis results in even distribution of one bacterium in each daughter cell.[14]
↑ Chang, K. P. (1974). "Ultrastructure of symbiotic bacteria in normal and antibiotic-treated Blastocrithidia culicis and Crithidia oncopelti". The Journal of Protozoology. 21 (5): 699–707. doi:10.1111/j.1550-7408.1974.tb03733.x. PMID4217371.
↑ Loyola-Machado, Ana Carolina; Azevedo-Martins, Allan Cézar; Catta-Preta, Carolina Moura Costa; de Souza, Wanderley; Galina, Antonio; Motta, Maria Cristina M. (2017). "The Symbiotic Bacterium Fuels the Energy Metabolism of the Host Trypanosomatid Strigomonas culicis". Protist. 168 (2): 253–269. doi:10.1016/j.protis.2017.02.001. PMID28371652.
1 2 Brum, Felipe Lopes; Catta-Preta, Carolina Moura Costa; de Souza, Wanderley; Schenkman, Sergio; Elias, Maria Carolina; Motta, Maria Cristina Machado (2014). "Structural characterization of the cell division cycle in Strigomonas culicis, an endosymbiont-bearing trypanosomatid". Microscopy and Microanalysis. 20 (1): 228–237. Bibcode:2014MiMic..20..228B. doi:10.1017/S1431927613013925. PMID24397934. S2CID29468549.
This page is based on this Wikipedia article Text is available under the CC BY-SA 4.0 license; additional terms may apply. Images, videos and audio are available under their respective licenses.
