| IUPAC name |
3D model (JSmol)
CompTox Dashboard (EPA)
|Molar mass||270.240 g·mol−1|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Thunberginol A is an isocoumarin found in Hydrangea macrophyllaand the herbal preparation hydrangeae dulcis folium which is produced from its leaves.
Hydrangea is a genus of 70–75 species of flowering plants native to Asia and the Americas. By far the greatest species diversity is in eastern Asia, notably Korea, China, and Japan. Most are shrubs 1 to 3 meters tall, but some are small trees, and others lianas reaching up to 30 m (98 ft) by climbing up trees. They can be either deciduous or evergreen, though the widely cultivated temperate species are all deciduous.
Hydrangea macrophylla is a species of flowering plant in the family Hydrangeaceae, native to Japan. It is a deciduous shrub growing to 2 m (7 ft) tall by 2.5 m (8 ft) broad with large heads of pink or blue flowers in summer and autumn. Common names include bigleaf hydrangea, French hydrangea, lacecap hydrangea, mophead hydrangea, penny mac and hortensia. It is widely cultivated in many parts of the world in many climates. It is not to be confused with H. aspera 'Macrophylla'.
Hydrangea quercifolia, commonly known by its translation oakleaf hydrangea or oak-leaved hydrangea, is a species of flowering plant native to the Southeastern United States, in woodland habitats from North Carolina west to Tennessee, and south to Florida and Louisiana. A deciduous shrub with white showy flower heads, it is a commonly grown garden plant. Numerous cultivars are available commercially.
Necdin is a protein that in humans is encoded by the NDN gene.
G protein-coupled receptor 177 (GPR177), commonly known as Wntless, is a human gene that encodes a receptor for Wnt proteins in Wnt-secreting cells.
Bassia scoparia is a large annual herb in the family Amaranthaceae native to Eurasia. It has been introduced to many parts of North America, where it is found in grassland, prairie, and desert shrub ecosystems. Its common names include burningbush, ragweed, summer cypress, mock-cypress, kochia, belvedere, Mexican firebrush, and Mexican fireweed.
AS-8112 is a synthetic compound that acts as a selective antagonist at the dopamine receptor subtypes D2 and D3, and the serotonin receptor 5-HT3. It has potent antiemetic effects in animal studies and has been investigated for potential medical use.
A metalloanthocyanin is a chemical complex giving color to petals of certain plants.
Osemozotan (MKC-242) is a selective 5-HT1A receptor agonist with some functional selectivity, acting as a full agonist at presynaptic and a partial agonist at postsynaptic 5-HT1A receptors. 5-HT1A receptor stimulation influences the release of various neurotransmitters including serotonin, dopamine, norepinephrine, and acetylcholine. 5-HT1A receptors are inhibitory G protein-coupled receptor. Osemozotan has antidepressant, anxiolytic, antiobsessional, serenic, and analgesic effects in animal studies, and is used to investigate the role of 5-HT1A receptors in modulating the release of dopamine and serotonin in the brain, and their involvement in addiction to abused stimulants such as cocaine and methamphetamine.
Momordin is one of several saponins derived from oleanolic acid, a triterpenoid. These chemical compounds are found in some plants of the genus Momordica, which includes the bitter melon and the balsam apple, as well as in other Asian herbal medicine plants such as Kochia scoparia and Ampelopsis radix.
Hydrangenol is a dihydroisocoumarin. It can be found in Hydrangea macrophylla, as well as its 8-O-glucoside. (-)-hydrangenol 4'-O-glucoside and (+)-hydrangenol 4'-O-glucoside can be found in Hydrangeae Dulcis Folium, the processed leaves of H. macrophylla var. thunbergii.
Phyllodulcin is a dihydroisocoumarin found in Hydrangea macrophylla and Hydrangea serrata. It is a sweetener 400-800 sweeter than sugar.
Thunberginol B is an isocoumarin found in Hydrangeae Dulcis Folium, the processed leaves of Hydrangea macrophylla var. thunbergii.
Thunberginol C is a dihydroisocoumarin found in Hydrangeae Dulcis Folium, the processed leaves of Hydrangea macrophylla var. thunbergii.
Thunberginol D is a dihydroisocoumarin found in Hydrangeae Dulcis Folium, the processed leaves of Hydrangea macrophylla var. thunbergii.
Thunberginol E is a dihydroisocoumarin found in Hydrangeae Dulcis Folium, the processed leaves of Hydrangea macrophylla var. thunbergii.
Thunberginol F is a phthalide found in Hydrangea macrophylla.
Thunberginol G is a dihydroisocoumarin found in Hydrangeae Dulcis Folium, the processed leaves of Hydrangea macrophylla var. thunbergii.
MGS-0039 is a drug that is used in neuroscientific research, which acts as a potent and selective antagonist for group II of the metabotropic glutamate receptors (mGluR2/3). It produces antidepressant and anxiolytic effects in animal studies, and has been shown to boost release of dopamine and serotonin in specific brain areas. Research has suggested this may occur through a similar mechanism as that suggested for the similarly glutamatergic drug ketamine.
Hydrangeic acid is a stilbenoid found in the leaves of Hydrangea macrophylla.
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