Undurti Narasimha Das

Last updated

Undurti Narasimha Das
Born (1950-06-28) 28 June 1950 (age 73)
NationalityIndian
Alma mater
Known forStudies on Endocrinology and Rheumatology
Awards
  • 1988  ICMR Shakuntala Amirchand Prize
  • 1992  Shanti Swarup Bhatnagar Prize
  • 1992 Association of Physicians of India Dr. Coelho Memorial Prize
  • 1992 Japanese Society of Clinical Chemistry Regional Research Award
  • 1992 Yagnavalki Sangham Award
  • 1992 PSMA Distinguished Citizen Award
  • 1994 KAPI Bobba Dharma Rao Prize
Scientific career
Fields
Institutions

Undurti Narasimha Das (born 1950) shortly Undurti N. Das and U. N. Das is an Indian clinical immunologist, endocrinologist and the founder president and chief executive officer of UND Life Sciences. [1] Additionally, he serves as the Chief Medical Officer and the Chairman of the Scientific Advisory Board of Asha Nutrition Sciences, Inc. [2] An elected fellow of the National Academy of Medical Sciences, [3] Das is known for his researches in the fields of Immunology, Endocrinology and Rheumatology. [4] He holds a number of patents for his work [5] The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards for his contributions to Medical Sciences in 1992. [6] [note 1]

Contents

Biography

Osmania Medical College Osmania Medical College Koti.jpg
Osmania Medical College

Born to Kameshwari and Undurti Sitarama Swamy on 28 June 1950 at Kakinada, a large city in the south Indian state of Andhra Pradesh, Undurti N. Das graduated in medicine from Andhra Medical College of the Andhra University in 1973. [7] Subsequently, he joined Osmania Medical College as a senior research fellow of the Indian Council of Medical Research and the Council of Scientific and Industrial Research, simultaneously pursuing his higher studies to secure an MD in 1981. He continued at the institution at the Department of Genetics as an ICMR Research Associate, doing his post-doctoral work for 3 years. In 1984, he moved to Canada to join Efamol Research Institute, Kentville, as a scientist, where he stayed for two years, and on his return to India in 1986, he joined Nizam's Institute of Medical Sciences as an associate professor at the department of clinical pharmacology and medical research. [5] He served the institution till 1996, holding the position of a professor from 1990 onward. For the next three years, he was with L. V. Prasad Eye Institute as a professor and the head of the Division of Internal Medicine, Clinical Immunology and Biochemistry. In 1999, he had his second stint abroad, this time in the US, where he chaired EFA Sciences, Norwood as its research director. His service at EFA lasted till 2004, during which period he also served as a research professor of surgery, nutrition, and physiology at the State University of New York Upstate Medical University from 2003 to 2004. That year, he founded UND Life Sciences at Shaker Heights, Ohio, a biotechnology company, [8] and became its founder president and chief executive officer. [9] Between 2007 and 2009, he had a brief stay in India as the Research Director of IKP Centre for Technologies in Public Health, Chennai. [7]

Das is married to Lakshmi and the couple has two children, Arundhati and Aditya. He holds the positions of the CEO and research director of UND Life Sciences [10] and is a director of Primrose Biosciences, [11] a Hyderabad-based company involved in research and experimental development in the field of natural sciences and engineering. [12]

On January 1, 2013, Dr. Das joined Asha Nutrition Sciences, Inc. as the Chief Medical Officer and the Chairman of the Scientific Advisory Board. [13]

Legacy

Glioma - MRI MRI glioma 28 yr old male.JPG
Glioma – MRI

Researches of U. N. Das are focused on various disease processes and his researches have revealed the tumoricidal properties of cis-unsaturated fatty acids as well as the role of gamma-Linolenic acid in controlling the progress of glioma, a type of tumor which affects brain and spinal cord. [14] He has also worked on drug development to combat diseases and conditions such as obesity, cancer, diabetes, hypertension and schizophrenia. [15] [16] His researches have been documented by way of several articles; [17] [note 2] ResearchGate an online repository of scientific articles has listed 500 of them. [17] Besides, he has authored three books, viz. Metabolic Syndrome Pathophysiology: The Role of Essential Fatty Acids, [18] Molecular Basis of Health and Disease [19] [note 3] and A Perinatal Strategy For Preventing Adult Disease: The Role of Long-Chain Polyunsaturated Fatty Acids. [20] He holds a number of patents for his work, which include "Method of potentiating the action of 2-methoxyoestradiol, statins and C-peptide of proinsulin, [21] Method(s) of stabilizing and potentiating the actions and administration of brain-derived neurotrophic factor (BDNF) [22] Method of stabilizing and potentiating the action of anti-angiogenic substances, [23] Method(s) of preventing, arresting, reversing and treatment of atherosclerosis, [24] and Methods for selectively occluding blood supplies to neoplasias [25] and Butyrylcholinesterase as a marker of low-grade systemic inflammation. [26]

Das is the editor-in-chief of Lipids in Health and Disease, a journal published by BioMed Central [27] and Current Nutrition & Food Science, published by Bentham Science. [28] [note 4] He is the section editor of Medicine journal, [29] a member of the editorial board of the controversial and non-peer reviewed journal Medical Hypotheses [30] and the Journal of Geriatric Cardiology [31] and sits in the scientific advisory board of Techno Scienze Publisher [32] which publishes a number of journals. [33] He is also a member of the editorial review board of Journal of Applied Research in Clinical and Experimental Therapeutics [34] and has been associated with a number of other journals as a member of their editorial boards or the Panel of Reviewers which include World Journal of Diabetes, [35] European Journal of General Medicine, Journal of the Association of Physicians of India, Frontiers in Biosciences, Diabetes Review Letters, Open Colorectal Cancer Journal, Indian Journal of Medical Research [36] and Gene Therapy and Molecular Biology. [7] He has also been a member of the International Advisory Board of the II International Conference on Functional Foods for the Prevention and Treatment of Chronic Diseases, organized by Functional Foods Center, held in November, 2005 at Richardson, Texas; [37]

Awards and honors

Das, a Ramalingaswamy Re-entry Fellow of the Department of Biotechnology, [10] received the Shakuntala Amirchand Prize of the Indian Council of Medical Research in 1988 [7] and the Council of Scientific and Industrial Research awarded him Shanti Swarup Bhatnagar Prize, one of the highest Indian science awards in 1992. [38] He delivered the Dr. Coelho Memorial Award Oration of Association of Physicians of India in 1992; [9] the same year as he received the Regional Research Award of the Japanese Society of Clinical Chemistry.[ citation needed ] He also received two minor awards in 1992 viz. Yagnavalki Sangham Award and Distinguished Citizen Award of Pramukh Swamy Maharaj of Aksharadham and the Karnataka Association of Physicians of India awarded him the Bobba Dharma Rao Prize in 1994. [7] In between, the National Academy of Medical Sciences elected him as a fellow in 1992 [39] and the Indian College of Physicians followed suit in 1993. [7] He is also a fellow of the Royal Society of Chemistry, a founder member of Telangana Academy of Sciences [40] and a member of science organizations such as New York Academy of Sciences, American Association for the Advancement of Science and Society for Experimental Biology and Medicine, New York.[ citation needed ]

Selected bibliography

Books

Articles

Reviews

Patents

See also

Notes

  1. Long link - please select award year to see details
  2. Please see Selected bibliography section
  3. Published under Ramalingaswami Re-entry fellowship of the Department of Biotechnology [10]
  4. Das is a former member of the editorial boards of four other Bentham Science publications viz. Open Nutrition Journal, Open Nutrition Reviews, Open Nutrition Letters and Current Pharmaceutical Biotechnology. [7]

Related Research Articles

<span class="mw-page-title-main">Fat</span> Esters of fatty acid or triglycerides

In nutrition, biology, and chemistry, fat usually means any ester of fatty acids, or a mixture of such compounds, most commonly those that occur in living beings or in food.

Omega−3 fatty acids, also called Omega−3 oils, ω−3 fatty acids or n−3 fatty acids, are polyunsaturated fatty acids (PUFAs) characterized by the presence of a double bond, three atoms away from the terminal methyl group in their chemical structure. They are widely distributed in nature, being important constituents of animal lipid metabolism, and they play an important role in the human diet and in human physiology. The three types of omega−3 fatty acids involved in human physiology are α-linolenic acid (ALA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). ALA can be found in plants, while DHA and EPA are found in algae and fish. Marine algae and phytoplankton are primary sources of omega−3 fatty acids. DHA and EPA accumulate in fish that eat these algae. Common sources of plant oils containing ALA include walnuts, edible seeds, and flaxseeds as well as hempseed oil, while sources of EPA and DHA include fish and fish oils, and algae oil.

<span class="mw-page-title-main">Dietary supplement</span> Product providing additional nutrients

A dietary supplement is a manufactured product intended to supplement a person's diet by taking a pill, capsule, tablet, powder, or liquid. A supplement can provide nutrients either extracted from food sources, or that are synthetic. The classes of nutrient compounds in supplements include vitamins, minerals, fiber, fatty acids, and amino acids. Dietary supplements can also contain substances that have not been confirmed as being essential to life, and so are not nutrients per se, but are marketed as having a beneficial biological effect, such as plant pigments or polyphenols. Animals can also be a source of supplement ingredients, such as collagen from chickens or fish for example. These are also sold individually and in combination, and may be combined with nutrient ingredients. The European Commission has also established harmonized rules to help insure that food supplements are safe and appropriately labeled.

Essential fatty acids, or EFAs, are fatty acids that humans and other animals must ingest because the body requires them for good health, but cannot synthesize them.

α-Linolenic acid Chemical compound

α-Linolenic acid, also known as alpha-Linolenic acid (ALA), is an n−3, or omega-3, essential fatty acid. ALA is found in many seeds and oils, including flaxseed, walnuts, chia, hemp, and many common vegetable oils.

A saturated fat is a type of fat in which the fatty acid chains have all single bonds. A fat known as a glyceride is made of two kinds of smaller molecules: a short glycerol backbone and fatty acids that each contain a long linear or branched chain of carbon (C) atoms. Along the chain, some carbon atoms are linked by single bonds (-C-C-) and others are linked by double bonds (-C=C-). A double bond along the carbon chain can react with a pair of hydrogen atoms to change into a single -C-C- bond, with each H atom now bonded to one of the two C atoms. Glyceride fats without any carbon chain double bonds are called saturated because they are "saturated with" hydrogen atoms, having no double bonds available to react with more hydrogen.

<span class="mw-page-title-main">Arachidonic acid</span> Fatty acid used metabolically in many organisms

Arachidonic acid is a polyunsaturated omega-6 fatty acid 20:4(ω-6), or 20:4(5,8,11,14). It is structurally related to the saturated arachidic acid found in cupuaçu butter. Its name derives from the Neo-Latin word arachis (peanut), but peanut oil does not contain any arachidonic acid.

<span class="mw-page-title-main">Omega-6 fatty acid</span> Fatty acids where the sixth bond is double

Omega-6 fatty acids are a family of polyunsaturated fatty acids that have in common a final carbon-carbon double bond in the n-6 position, that is, the sixth bond, counting from the methyl end.

Linoleic acid (LA) is an organic compound with the formula HOOC(CH
2
)
7
CH=CHCH
2
CH=CH(CH
2
)
4
CH
3
. Both alkene groups are cis. It is a fatty acid sometimes denoted 18:2 (n-6) or 18:2 cis-9,12. A linoleate is a salt or ester of this acid.

In biochemistry and nutrition, a monounsaturated fat is a fat that contains a monounsaturated fatty acid (MUFA), a subclass of fatty acid characterized by having a double bond in the fatty acid chain with all of the remaining carbon atoms being single-bonded. By contrast, polyunsaturated fatty acids (PUFAs) have more than one double bond.

<span class="mw-page-title-main">Docosahexaenoic acid</span> Chemical compound

Docosahexaenoic acid (DHA) is an omega-3 fatty acid that is a primary structural component of the human brain, cerebral cortex, skin, and retina. In physiological literature, it is given the name 22:6(n-3). It can be synthesized from alpha-linolenic acid or obtained directly from maternal milk, fatty fish, fish oil, or algae oil.

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<span class="mw-page-title-main">Egg oil</span> Oil derived from yolk of chicken eggs

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George Edward Billman is an American physiologist and professor at Ohio State University. After receiving a Ph.D from the University of Kentucky in 1980, Billman began his professional career at the University of Oklahoma. In 1984, he joined the Ohio State staff, where he became an associate professor in 1990 and a full professor in 1996.

<span class="mw-page-title-main">Cooking oil</span> Oil consumed by humans, of vegetable or animal origin

Cooking oil is a plant or animal liquid fat used in frying, baking, and other types of cooking. Oil allows higher cooking temperatures than water, making cooking faster and more flavorful, while likewise distributing heat, reducing burning and uneven cooking. It sometimes imparts its own flavor. Cooking oil is also used in food preparation and flavoring not involving heat, such as salad dressings and bread dips.

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Ravinder Goswami is an Indian endocrinologist and professor at the department of endocrinology and metabolism at the All India Institute of Medical Sciences, Delhi. Known for his research on vitamin D deficiency, Goswami is an elected fellow of National Academy of Sciences, India and Indian Academy of Sciences. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards for his contributions to Medical Sciences in 2008.

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References

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  19. Undurti N. Das (2 April 2011). Molecular Basis of Health and Disease. Springer Science & Business Media. ISBN   978-94-007-0495-4.
  20. Undurti N. Das (31 May 2002). A Perinatal Strategy For Preventing Adult Disease: The Role Of Long-Chain Polyunsaturated Fatty Acids: The Role of Long-Chain Polyunsaturated Fatty Acids. Springer Science & Business Media. ISBN   978-1-4020-7070-9.
  21. Undurti Narasimha Das (20 June 2002). "Method of potentiating the action of 2-methoxyoestradiol, statins and C-peptide of proinsulin". US Patent 20020077317. Justia Patents.
  22. Undurti Narasimha Das, Appa Rao Allam (25 September 2008). "Method(s) of stabilizing and potentiating the actions and administration of brain-derived neurotrophic factor (BDNF)". US Patent 20080234197. Justia Patents.
  23. Undurti Narasimha Das (23 February 2010). "Method of stabilizing and potentiating the action of anti-angiogenic substances". US Patent 7666910. Justia Patents.
  24. Undurti Narasimha Das, Appa Rao Allam (10 April 2012). "Method(s) of preventing, arresting, reversing and treatment of atherosclerosis". US Patent 8153392. Justia Patents.
  25. Undurti Narasimha Das (16 January 2003). "Methods for selectively occluding blood supplies to neoplasias". US20030013759 A1. Google Patents.
  26. Appa Rao Allam, Sridhar Gumpeny, Undurti Narasimha Das (7 August 2008). "Butyrylcholinesterase as a marker of low-grade systemic inflammation". US20080187944 A1. Google Patents.{{cite web}}: CS1 maint: multiple names: authors list (link)
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