HMGB3

HMGB3
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 2EQZ, 2YQI
Identifiers
Aliases	HMGB3 , HMG-2a, HMG-4, HMG2A, HMG4, high mobility group box 3
External IDs	OMIM: 300193 HomoloGene: 84734 GeneCards: HMGB3
Gene location (Human) Chr. X chromosome (human) [1] Band Xq28 Start 150,980,509 bp [1] End 150,990,771 bp [1]
Gene ontology Molecular function • DNA binding • double-stranded DNA binding • DNA binding, bending • GO:0001948 protein binding • four-way junction DNA binding • RNA binding • transcription factor binding Cellular component • cytoplasm • cell nucleus • chromosome • nuclear chromatin Biological process • multicellular organism development • immune system process • DNA recombination • innate immune system • regulation of transcription, DNA-templated • transcription, DNA-templated • DNA geometric change • negative regulation of B cell differentiation • negative regulation of myeloid cell differentiation • chromatin remodeling • regulation of transcription from RNA polymerase II promoter • positive regulation of innate immune response • positive regulation of transcription from RNA polymerase II promoter Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	3149	n/a
Ensembl	ENSG00000029993	n/a
UniProt	O15347	n/a
RefSeq (mRNA)	NM_005342 NM_001301228 NM_001301229 NM_001301231	n/a
RefSeq (protein)	NP_001288157 NP_001288158 NP_001288160 NP_005333	n/a
Location (UCSC)	Chr X: 150.98 – 150.99 Mb	n/a
PubMed search	[2]	n/a
Wikidata
View/Edit Human

High-mobility group protein B3 is a protein that in humans is encoded by the HMGB3 gene. ^{[3] [4]}

References

1. GRCh38: Ensembl release 89: ENSG00000029993 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. Vaccari T, Beltrame M, Ferrari S, Bianchi ME (April 1998). "Hmg4, a new member of the Hmg1/2 gene family". Genomics. 49 (2): 247–52. doi:10.1006/geno.1998.5214. PMID   9598312.
4. "Entrez Gene: HMGB3 high-mobility group box 3".

Further reading

• Davis DL, Burch JB (April 1992). "Isolation of a chicken HMG2 cDNA clone and evidence for an HMG2-specific 3'-untranslated region". Gene. 113 (2): 251–6. doi:10.1016/0378-1119(92)90403-C. PMID   1572546.
• Shirakawa H, Tsuda K, Yoshida M (May 1990). "Primary structure of non-histone chromosomal protein HMG2 revealed by the nucleotide sequence". Biochemistry. 29 (18): 4419–23. doi:10.1021/bi00470a022. PMID   2350545.
• Wilke K, Wiemann S, Gaul R, Gong W, Poustka A (October 1997). "Isolation of human and mouse HMG2a cDNAs: evidence for an HMG2a-specific 3' untranslated region". Gene. 198 (1–2): 269–74. doi:10.1016/S0378-1119(97)00324-7. PMID   9370291.
• Hartley JL, Temple GF, Brasch MA (November 2000). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.
• Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (October 2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (January 2006). "The LIFEdb database in 2006". Nucleic Acids Research. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.

External links

• HMGB3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
• PDBe-KB provides an overview of all the structure information available in the PDB for Human High mobility group protein B3 (HMGB3)