2-Methylindole

Last updated
2-Methylindole
2-Methylindole Structural formula V.1.svg
2-Methylindole-3D-balls.png
Names
Preferred IUPAC name
2-Methyl-1H-indole
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.002.181 OOjs UI icon edit-ltr-progressive.svg
PubChem CID
UNII
  • InChI=1S/C9H9N/c1-7-6-8-4-2-3-5-9(8)10-7/h2-6,10H,1H3 Yes check.svgY
    Key: BHNHHSOHWZKFOX-UHFFFAOYSA-N Yes check.svgY
  • Cc2cc1ccccc1[nH]2
Properties
C9H9N
Molar mass 131.178 g·mol−1
AppearanceYellow viscous liquid
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Yes check.svgY  verify  (what is  Yes check.svgYX mark.svgN ?)

Methylketol or 2-methylindole is a mildly toxic and slightly flammable organic compound which occurs as a white solid which turns brown over time. [1] [2] It has chemical formula C 9 H 9 N . [3]

Methylketol is used as an intermediate for synthesizing dyes, [4] pigments, [5] optical brighteners, and pharmaceuticals. [6]

See also

References

  1. ↑ Brown, Daniel R.; Clark, Bryan W.; Garner, Lindsey V. T.; Di Giulio, Richard T. (June 2015). "Zebrafish cardiotoxicity: the effects of CYP1A inhibition and AHR2 knockdown following exposure to weak aryl hydrocarbon receptor agonists". Environmental Science and Pollution Research International. 22 (11): 8329–8338. Bibcode:2015ESPR...22.8329B. doi:10.1007/s11356-014-3969-2. ISSN   1614-7499. PMC   4442063 . PMID   25532870.
  2. ↑ Brown, D. R.; Clark, B. W.; Garner, L. V. T.; Di Giulio, R. T. (October 2016). "Embryonic cardiotoxicity of weak aryl hydrocarbon receptor agonists and CYP1A inhibitor fluoranthene in the Atlantic killifish (Fundulus heteroclitus)". Comparative Biochemistry and Physiology. Toxicology & Pharmacology. 188: 45–51. doi:10.1016/j.cbpc.2016.05.005. ISSN   1532-0456. PMID   27211013.
  3. ↑ Parker, Amie; Lamata, Pilar; Viguri, Fernando; Rodríguez, Ricardo; López, José A.; Lahoz, Fernando J.; García-Orduña, Pilar; Carmona, Daniel (2020-10-12). "Half-sandwich complexes of osmium containing guanidine-derived ligands". Dalton Transactions. 49 (39): 13601–13617. doi:10.1039/d0dt02713h. hdl: 10261/233133 . ISSN   1477-9234. PMID   32975256. S2CID   221913494.
  4. ↑ Casas-Catalán, María José; Doménech-Carbó, María Teresa (May 2005). "Identification of natural dyes used in works of art by pyrolysis-gas chromatography/mass spectrometry combined with in situ trimethylsilylation". Analytical and Bioanalytical Chemistry. 382 (2): 259–268. doi:10.1007/s00216-005-3064-0. ISSN   1618-2642. PMID   15782338. S2CID   44407380.
  5. ↑ Shaki, Hanieh; Gharanjig, Kamaladin; Khosravi, Alireza (July 2015). "Synthesis and investigation of antimicrobial activity and spectrophotometric and dyeing properties of some novel azo disperse dyes based on naphthalimides". Biotechnology Progress. 31 (4): 1086–1095. doi:10.1002/btpr.2107. ISSN   1520-6033. PMID   25967675. S2CID   25349059.
  6. ↑ Ozcan-Sezer, Senem; Ince, Elif; Akdemir, Atilla; Ceylan, Özlem Öztürk; Suzen, Sibel; Gurer-Orhan, Hande (May 2019). "Aromatase inhibition by 2-methyl indole hydrazone derivatives evaluated via molecular docking and in vitro activity studies". Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 49 (5): 549–556. doi:10.1080/00498254.2018.1482029. ISSN   1366-5928. PMID   29804490. S2CID   44062839.


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