The International Standard Book Number (ISBN) is a numeric commercial book identifier that is intended to be unique. Publishers purchase or receive ISBNs from an affiliate of the International ISBN Agency.
The Philippines, officially the Republic of the Philippines, is an archipelagic country in Southeast Asia. It is situated in the western Pacific Ocean and consists of around 7,641 islands that are broadly categorized under three main geographical divisions from north to south: Luzon, Visayas, and Mindanao. The Philippines is bounded by the South China Sea to the west, the Philippine Sea to the east, and the Celebes Sea to the southwest. It shares maritime borders with Taiwan to the north, Japan to the northeast, Palau to the east and southeast, Indonesia to the south, Malaysia to the southwest, Vietnam to the west, and China to the northwest. The Philippines covers an area of 300,000 km2 (120,000 sq mi) and, as of 2021, it had a population of around 109 million people, making it the world's thirteenth-most-populous country. The Philippines has diverse ethnicities and cultures throughout its islands. Manila is the country's capital, while the largest city is Quezon City; both lie within the urban area of Metro Manila.
Skatole or 3-methylindole is an organic compound belonging to the indole family. It occurs naturally in the feces of mammals and birds and is the primary contributor to fecal odor. In low concentrations, it has a flowery smell and is found in several flowers and essential oils, including those of orange blossoms, jasmine, and Ziziphus mauritiana.
Sodium amide, commonly called sodamide, is the inorganic compound with the formula NaNH2. It is a salt composed of the sodium cation and the azanide anion. This solid, which is dangerously reactive toward water, is white, but commercial samples are typically gray due to the presence of small quantities of metallic iron from the manufacturing process. Such impurities do not usually affect the utility of the reagent. NaNH2 conducts electricity in the fused state, its conductance being similar to that of NaOH in a similar state. NaNH2 has been widely employed as a strong base in organic synthesis.
7-Methylindole is a mildly toxic off-white crystalline organic compound with chemical formula C9H9N.
5-Methylindole is an irritating organic compound with chemical formula C9H9N. 5-Methylindole is used as an intermediate in the synthesis of compounds with a variety of pharmacological properties, such as staurosporine-like bisindole inhibitors of protein kinases.
The Bartoli indole synthesis is the chemical reaction of ortho-substituted nitroarenes and nitrosoarenes with vinyl Grignard reagents to form substituted indoles.
The September 11 attacks, commonly known as 9/11, were four coordinated suicide terrorist attacks carried out by the militant Islamist extremist network al-Qaeda against the United States on September 11, 2001. That morning, nineteen terrorists hijacked four commercial airliners scheduled to travel from the East Coast to California. The hijackers crashed the first two planes into the Twin Towers of the World Trade Center in New York City, and the third into The Pentagon in Arlington County, Virginia near Washington, D.C. The fourth plane was also intended to hit a federal government building in D.C., but crashed in a field following a passenger revolt. The attacks killed nearly 3,000 people and instigated the global war on terror.
Fog fever is a refeeding syndrome in cattle, clinically named acute bovine pulmonary emphysema and edema (ABPEE) and bovine atypical interstitial pneumonia. This veterinary disease in adult cattle follows an abrupt move from feedlot to 'foggage pasture'. Clinical signs begin within 1 to 14 days and death may follow within 2 to 4 days. The condition can affect up to 50% of the herd, and around 30% of affected cattle may die as a result. This metabolic nutritional-respiratory disturbance has also been reported in other ruminants and on a wide variety of grasses, alfalfa, rape, kale, and turnip tops.
Isoindoline is a heterocyclic organic compound with the molecular formula C8H9N. The parent compound has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing ring. The compound's structure is similar to indoline except that the nitrogen atom is in the 2 position instead of the 1 position of the five-membered ring. Isoindoline itself is not commonly encountered, but several derivatives are found in nature and some synthetic derivatives are commercially valuable drugs, e.g. pazinaclone.
Cytochrome P450 2F1 is a protein that in humans is encoded by the CYP2F1 gene.
iOS is a mobile operating system developed by Apple Inc. exclusively for its hardware. It is the operating system that powers many of the company's mobile devices, including the iPhone; the term also includes the system software for iPads predating iPadOS—which was introduced in 2019—as well as on the iPod Touch devices—which were discontinued in mid-2022. It is the world's second-most widely installed mobile operating system, after Android. It is the basis for three other operating systems made by Apple: iPadOS, tvOS, and watchOS. It is proprietary software, although some parts of it are open source under the Apple Public Source License and other licenses.
Bopindolol (INN) is a beta blocker. It is an ester which acts as a prodrug for its active metabolite 4-(3-t-butylamino-2-hydroxypropoxy)-2-methylindole.
Indole is an aromatic, heterocyclic, organic compound with the formula C8H7N. It has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered pyrrole ring. Indole is widely distributed in the natural environment and can be produced by a variety of bacteria. As an intercellular signal molecule, indole regulates various aspects of bacterial physiology, including spore formation, plasmid stability, resistance to drugs, biofilm formation, and virulence. The amino acid tryptophan is an indole derivative and the precursor of the neurotransmitter serotonin.
The molecular formula C9H9N (molar mass: 131.17 g/mol) may refer to:
JWH-203 (1-pentyl-3-(2-chlorophenylacetyl)indole) is an analgesic chemical from the phenylacetylindole family that acts as a cannabinoid agonist with approximately equal affinity at both the CB1 and CB2 receptors, having a Ki of 8.0 nM at CB1 and 7.0 nM at CB2. It was originally discovered by, and named after, John W. Huffman, but has subsequently been sold without his permission as an ingredient of synthetic cannabis smoking blends. Similar to the related 2'-methoxy compound JWH-250, the 2'-bromo compound JWH-249, and the 2'-methyl compound JWH-251, JWH-203 has a phenylacetyl group in place of the naphthoyl ring used in most aminoalkylindole cannabinoid compounds, and has the strongest in vitro binding affinity for the cannabinoid receptors of any compound in the phenylacetyl group.
Eudistoma is a genus of sea squirts belonging to the class Ascidiacea. It was first described in 1909 by Maurice Caullery. Originally it was thought to be a subgenus of Distoma. Eudistoma is the most species-rich genus in the family Polycitordae, with 124 valid species as of 2014. They are found in tropical and temperate waters; some species are also found in the Antarctic and subtropical area.
D-15414 is a nonsteroidal weak estrogen of the 2-phenylindole group which was never marketed. It is the major metabolite of the selective estrogen receptor modulator (SERM) zindoxifene (D-16726). D-15414 has high affinity for the estrogen receptor (ER) and inhibits the growth of ER-positive MCF-7 breast cancer cells in vitro. However, contradictorily, subsequent research found that the drug produced fully estrogenic effects in vitro similarly to but less actively than estradiol, with no antiestrogenic activity observed. The reason for the discrepancy between the findings is unclear, though may be due to methodology. The unexpected estrogenic activity of D-15414 may be responsible for the failure of zindoxifene in clinical trials as a treatment for breast cancer.
Olsenella scatoligenes is a Gram-positive, saccharolytic, non-spore-forming, strictly anaerobic and non-motile bacterium from the genus of Olsenella which has been isolated from faeces of a pig from the Aarhus University in Denmark.Olsenella scatoligenes produces 3-methylindole and 4-methylphenol.
The Hegedus indole synthesis is a name reaction in organic chemistry that allows for the generation of indoles through palladium(II)-mediated oxidative cyclization of ortho-alkenyl anilines. The reaction can still take place for tosyl-protected amines.
