| Singles | |
|---|---|
| 2021 St. Petersburg Open | |
| Champion |  Marin Čilić |
| Runner-up |  Taylor Fritz |
| Final score | 7–6(7–3), 4–6, 6–4 |
| Draw | 28 (4 Q / 3 WC ) |
| Seeds | 8 |
Andrey Rublev was the defending champion, [1] but lost in the quarterfinals to Botic van de Zandschulp.
Marin Čilić won the title, defeating Taylor Fritz in the final, 7–6(7–3), 4–6, 6–4.
The top four seeds received a bye into the second round.
Andrey Rublev (quarterfinals)
Denis Shapovalov (quarterfinals)
Roberto Bautista Agut (quarterfinals) Aslan Karatsev (second round) Taylor Fritz (final) Karen Khachanov (second round)
Alexander Bublik (second round) Sebastian Korda (second round)| Semifinals | Final | ||||||||||||
| Q |  Botic van de Zandschulp | 3 | 3 | ||||||||||
| Marin Čilić | 6 | 6 | |||||||||||
| Marin Čilić | 77 | 4 | 6 | ||||||||||
| 5 | Taylor Fritz | 63 | 6 | 4 | |||||||||
| 5 | Taylor Fritz | 5 | 6 | 6 | |||||||||
 Jan-Lennard Struff | 7 | 1 | 3 | ||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | A Rublev | 6 | 6 | ||||||||||||||||||||||||
 L Đere | 3 | 2 |  I Ivashka | 4 | 4 | ||||||||||||||||||||||
| I Ivashka | 6 | 6 | 1 | A Rublev | 3 | 4 | |||||||||||||||||||||
| Q | B van de Zandschulp | 6 | 6 | Q | B van de Zandschulp | 6 | 6 | ||||||||||||||||||||
| Q |  Y Nishioka | 2 | 2 | Q | B van de Zandschulp | 6 | 7 | ||||||||||||||||||||
| WC | N Serdarušić | 62 | 5 | 8 | S Korda | 2 | 5 | ||||||||||||||||||||
| 8 | S Korda | 77 | 7 | Q | B van de Zandschulp | 3 | 3 | ||||||||||||||||||||
| M Čilić | 6 | 6 | |||||||||||||||||||||||||
| 3 | R Bautista Agut | 6 | 6 | ||||||||||||||||||||||||
| Q | E Gerasimov | 5 | 4 | M McDonald | 3 | 2 | |||||||||||||||||||||
| M McDonald | 7 | 6 | 3 | R Bautista Agut | 4 | 6 | 3 | ||||||||||||||||||||
| M Čilić | 6 | 6 | M Čilić | 6 | 3 | 6 | |||||||||||||||||||||
| A Ramos Viñolas | 2 | 3 | M Čilić | 6 | 61 | 6 | |||||||||||||||||||||
 A Mannarino | 3 | 3 | 6 | K Khachanov | 4 | 77 | 4 | ||||||||||||||||||||
| 6 | K Khachanov | 6 | 6 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 5 | T Fritz | 6 | 6 | ||||||||||||||||||||||||
| Q |  E Ruusuvuori | 1 | 4 | 5 | T Fritz | 77 | 6 | ||||||||||||||||||||
| P Martínez | 3 | 2 | T Paul | 63 | 4 | ||||||||||||||||||||||
| T Paul | 6 | 6 | 5 | T Fritz | 6 | 6 | |||||||||||||||||||||
 J Millman | 6 | 6 | J Millman | 4 | 2 | ||||||||||||||||||||||
| WC |  Y Oliel | 1 | 1 | J Millman | 6 | 6 | |||||||||||||||||||||
| 4 | A Karatsev | 3 | 2 | ||||||||||||||||||||||||
| 5 | T Fritz | 5 | 6 | 6 | |||||||||||||||||||||||
| 7 | A Bublik | 6 | 6 | J-L Struff | 7 | 1 | 3 | ||||||||||||||||||||
| WC | E Tiurnev | 3 | 4 | 7 | A Bublik | 4 | 3 | ||||||||||||||||||||
| J-L Struff | 77 | 6 | J-L Struff | 6 | 6 | ||||||||||||||||||||||
| J Duckworth | 63 | 3 | J-L Struff | 6 | 6 | ||||||||||||||||||||||
 F Delbonis | 2 | 61 | 2 | D Shapovalov | 4 | 3 | |||||||||||||||||||||
| PR | P Andújar | 6 | 77 | PR | P Andújar | 6 | 3 | 0 | |||||||||||||||||||
| 2 | D Shapovalov | 2 | 6 | 6 | |||||||||||||||||||||||
Botic van de Zandschulp (qualified) Benjamin Bonzi (first round) Federico Coria (first round) Miomir Kecmanović (qualifying competition) Emil Ruusuvuori (qualified) Yoshihito Nishioka (qualified)
Mikael Ymer (first round) Egor Gerasimov (qualified)| First round | Qualifying competition | ||||||||||||
| 1 | Botic van de Zandschulp | 6 | |||||||||||
| Alt | Marc Polmans | 6r | |||||||||||
| 1 | Botic van de Zandschulp | 5 | 6 | 6 | |||||||||
| Alt | Evgeny Donskoy | 7 | 3 | 2 | |||||||||
| Alt | Evgeny Donskoy | 6 | 7 | ||||||||||
| 7 | Mikael Ymer | 2 | 5 | ||||||||||
| First round | Qualifying competition | ||||||||||||
| 2 | Benjamin Bonzi | 6 | 64 | 2 | |||||||||
| WC | Dmitry Popko | 4 | 77 | 6 | |||||||||
| WC | Dmitry Popko | 62 | 4 | ||||||||||
| 5 | Emil Ruusuvuori | 77 | 6 | ||||||||||
| PR | Gilles Simon | 0 | 3 | ||||||||||
| 5 | Emil Ruusuvuori | 6 | 6 | ||||||||||
| First round | Qualifying competition | ||||||||||||
| 3 | Federico Coria | 3 | 4 | ||||||||||
 Radu Albot | 6 | 6 | |||||||||||
| Radu Albot | 62 | 4 | |||||||||||
| 8 | Egor Gerasimov | 77 | 6 | ||||||||||
 Damir Džumhur | 1 | 66 | |||||||||||
| 8 | Egor Gerasimov | 6 | 78 | ||||||||||
| First round | Qualifying competition | ||||||||||||
| 4 | Miomir Kecmanović | 2 | 6 | 6 | |||||||||
| WC | Evgeny Karlovskiy | 6 | 4 | 1 | |||||||||
| 4 | Miomir Kecmanović | 3 | 6 | 2 | |||||||||
| 6 | Yoshihito Nishioka | 6 | 4 | 6 | |||||||||
| Alt | Roman Safiullin | 5 | 2 | ||||||||||
| 6 | Yoshihito Nishioka | 7 | 6 | ||||||||||
Botic van de Zandschulp is a Dutch professional tennis player. Van de Zandschulp has a career high ranking of world No. 29 in singles by the Association of Tennis Professionals (ATP), achieved on 16 May 2022. He is the current Dutch No. 1 men's singles player. He also has a career high doubles ranking of world No. 226, first achieved on 7 March 2022. Van de Zandschulp has won one ATP Challenger singles title in Hamburg and one ATP Challenger doubles title in Alphen.
Dominic Thiem was the defending champion, but chose to compete in the Laver Cup instead.
Karen Khachanov was the defending champion, but lost in the quarterfinals to Andreas Seppi.
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| Grand Slam events | |
|---|---|
| ATP Tour Masters 1000 | |
| ATP Tour 500 | |
| ATP Tour 250 |
|
| Team events | |
 – Tournaments are affected by the COVID-19 pandemic * – Tournaments are introduced due to the impact of the COVID-19 pandemic | |