ALDH3B2

Last updated

ALDH3B2
Identifiers
Aliases ALDH3B2 , ALDH8, aldehyde dehydrogenase 3 family member B2
External IDs OMIM: 601917; MGI: 1920708; GeneCards: ALDH3B2; OMA:ALDH3B2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_028545

RefSeq (protein)

NP_000686
NP_001026786
NP_001341274

NP_082821

Location (UCSC) Chr 11: 67.66 – 67.68 Mb Chr 19: 4.01 – 4.02 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Aldehyde dehydrogenase family 3 member B2 is an enzyme that, in humans, is encoded by the ALDH3B2 gene. [5] [6] [7]

Contents

This gene encodes a member of the aldehyde dehydrogenase family, a group of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The gene for this particular family member is over 10 kb in length. The expression of these transcripts is restricted to the salivary gland among the human tissues examined. Alternate transcriptional splice variants have been characterized. [7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000132746 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000037263 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Hsu LC, Chang WC (Dec 1996). "Sequencing and expression of the human ALDH8 encoding a new member of the aldehyde dehydrogenase family". Gene. 174 (2): 319–22. doi:10.1016/0378-1119(96)00087-X. PMID   8890755.
  6. Hsu LC, Chang WC, Yoshida A (Jun 1997). "Human aldehyde dehydrogenase genes, ALDH7 and ALDH8: genomic organization and gene structure comparison". Gene. 189 (1): 89–94. doi:10.1016/S0378-1119(96)00839-6. PMID   9161417.
  7. 1 2 "Entrez Gene: ALDH3B2 aldehyde dehydrogenase 3 family, member B2".

Further reading