Anthony Nolan

Last updated
Anthony Nolan
Formation1974
Founder Shirley Nolan
Legal status Registered charity
Purpose Health care in the UK
Location
  • 2 Heathgate Place, 75-87 Agincourt Road, London
Region served
UK
Chief Executive
Henny Braund
Website AnthonyNolan.org

Anthony Nolan is a UK charity that works in the areas of leukaemia and hematopoietic stem cell transplantation. It manages and recruits donors to the Anthony Nolan Register, which is part of an aligned registry that also includes the Welsh Bone Marrow Donor Registry, NHS Blood and Transplant's British Bone Marrow Registry and Deutsche KnochenMarkSpenderdatei (DKMS) UK. This aligned register is known as the Anthony Nolan & NHS Stem Cell Registry. [1] It also carries out research to help make bone marrow transplants more effective. [2]

Contents

History

The charity is named after Anthony Nolan (born 1971–died 1979), who did not suffer from leukaemia but from Wiskott–Aldrich syndrome, a rare inherited blood disorder. [3] It was founded by Anthony's mother Shirley Nolan (1942–2001) in 1974 as the Anthony Nolan Register. [3]

Initially based at the Westminster Children's Hospital, it moved to St Mary Abbots Hospital in 1978 and to its present offices, laboratory and research institute in north London, in the grounds of the Royal Free Hospital. The charity was renamed in 2001 as the Anthony Nolan Trust. [3] and again in 2010 to Anthony Nolan. [3]

In 2008 Anthony Nolan set up the UK's first dedicated cord blood bank, allowing mothers to safely donate the blood from their umbilical cord and placenta after they give birth, [4] the charity then use this blood in their stem cell transplants. In 2012 Anthony Nolan became the first stem cell register in the world to start recruiting 16-year-olds. [4]

Present day

Today the register has over 720,000 potential donors on it. [4] One of the charity's main aims is to recruit more male donors, as they are the most likely to be chosen by doctors to donate, and are selected for 54% of donations. [5]

A student organisation operating in universities throughout the UK known as 'Marrow' works with Anthony Nolan to recruit potential donors to the register and raise awareness of the charity and blood cancers within universities and their local communities. It was set up in 1998 at the University of Nottingham and now operates in more than 50 universities in the UK and worldwide. [6]

In 2014, Anthony Nolan was the official charity partner for the London Marathon. [7]

Midland Metro named an AnsaldoBreda T-69 tram in his honour. [8] Daniel De Gale (1987–2008), a leukaemia patient, inspired his mother Beverley and her partner, Orin Lewis, to set up the African-Caribbean Leukaemia Trust in June 1996. ACLT worked "in partnership with the ... Nolan Trust" to build the number of bone marrow donors, specifically of African, African Caribbean, and mixed parentage on the UK register. [9]

The organisation organizes several novel campaigns to increase the number of donors joining the registry. For example, it organised the Spit and Save a life campaign [10] in 2010 which featured Devaanshi Mehta (1996–2012), an aplastic anemia patient. During the campaign donors could join the registry and find out if they could save a life by simply giving a sample of their saliva. [ citation needed ]

Olivia Colman became Patron of Anthony Nolan in 2018. [11]

See also

Related Research Articles

<span class="mw-page-title-main">Bone marrow</span> Semi-solid tissue in the spongy portions of bones

Bone marrow is a semi-solid tissue found within the spongy portions of bones. In birds and mammals, bone marrow is the primary site of new blood cell production. It is composed of hematopoietic cells, marrow adipose tissue, and supportive stromal cells. In adult humans, bone marrow is primarily located in the ribs, vertebrae, sternum, and bones of the pelvis. Bone marrow comprises approximately 5% of total body mass in healthy adult humans, such that a man weighing 73 kg (161 lbs) will have around 3.7 kg (8 lbs) of bone marrow.

<span class="mw-page-title-main">Hematopoietic stem cell transplantation</span> Medical procedure to replace blood or immune stem cells

Hematopoietic stem-cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood, in order to replicate inside a patient and produce additional normal blood cells. HSCT may be autologous, syngeneic, or allogeneic.

<span class="mw-page-title-main">Blood donation in England</span>

In England, blood and other tissues are collected by NHS Blood and Transplant (NHSBT). NHSBT Blood Donation was previously known as the National Blood Service until it merged with UK Transplant in 2005 to form a NHS special health authority. Other official blood services in the United Kingdom include the Northern Ireland Blood Transfusion Service, the Scottish National Blood Transfusion Service and the Welsh Blood Service.

Stem-cell therapy uses stem cells to treat or prevent a disease or condition. As of 2024, the only FDA-approved therapy using stem cells is hematopoietic stem cell transplantation. This usually takes the form of a bone marrow or peripheral blood stem cell transplantation, but the cells can also be derived from umbilical cord blood. Research is underway to develop various sources for stem cells as well as to apply stem-cell treatments for neurodegenerative diseases and conditions such as diabetes and heart disease.

The National Marrow Donor Program (NMDP) is a nonprofit organization founded in 1987 and based in Minneapolis, Minnesota, that operates the Be The Match Registry of volunteer hematopoietic cell donors and umbilical cord blood units in the United States.

<span class="mw-page-title-main">World Marrow Donor Association</span>

World Marrow Donor Association (WMDA) is an organization based in Leiden, Netherlands, that coordinates the collection of the HLA phenotypes and other relevant data of volunteer hematopoietic cell donors and cord blood units across the globe.

<span class="mw-page-title-main">John Raymond Hobbs</span> British surgeon

John Raymond Hobbs MRCS, FRCP, FRCPath, FRCPaed was a professor who was at the forefront of the techniques of clinical immunology, protein biochemistry and bone marrow transplantation, specifically in child health.

Autologous stem-cell transplantation is the autologous transplantation of stem cells—that is, transplantation in which stem cells are removed from a person, stored, and later given back to that same person.

<span class="mw-page-title-main">Treosulfan</span> Medication given to people before they have a bone marrow transplant

Treosulfan, sold under the brand name Trecondi, is a medication given to people before they have a bone marrow transplant from a donor known as allogeneic hematopoietic stem cell transplantation. It is used as a 'conditioning' treatment to clear the bone marrow and make room for the transplanted bone marrow cells, which can then produce healthy blood cells. It is used together with another medicine called fludarabine in adults and children from one month of age with blood cancers as well as in adults with other severe disorders requiring a bone marrow transplant.

<span class="mw-page-title-main">Peripheral stem cell transplantation</span> Method of replacing blood-forming stem cells

Peripheral blood stem cell transplantation (PBSCT), also called "Peripheral stem cell support", is a method of replacing blood-forming stem cells. Stem cells can be destroyed through cancer treatments such as chemotherapy or radiation, as well as any blood-related diseases, such as leukemia, lymphoma, neuroblastoma and multiple myeloma. PBSCT is now a much more common procedure than its bone marrow harvest equivalent due to the ease and less invasive nature of the procedure. Studies suggest that PBSCT has a better outcome in terms of the number of hematopoietic stem cell yield.

<span class="mw-page-title-main">Gift of Life Marrow Registry</span> Public blood stem cell and bone marrow registry

The Gift of Life Marrow Registry is a non-profit organization founded in 1991 and headquartered in Boca Raton, Florida that operates a public blood stem cell and bone marrow registry while facilitating transplants for children and adults battling life-threatening illnesses, including leukemia, lymphoma, other cancers and genetic diseases.

<span class="mw-page-title-main">Devaanshi Mehta</span>

Devaanshi Mehta was a British - Indian student and humanitarian. She started the Asian Donor Campaign (ADC), a UK-based non-profit organisation whose goal is to raise awareness for the need to get more Asians to donate their blood, bone marrow and organs. ADC also raises funds for hospitals doing research into critical and life limiting illnesses.

John M. Goldman was a British haematologist, oncologist and medical researcher. A specialist in chronic myeloid leukaemia, Goldman conducted pioneering research into leukaemia treatment – he was instrumental in the development of bone marrow transplantation as a clinical method, and later in the development of the drug imatinib. He was also a prolific author of scientific papers, was involved with numerous medical charities and had a decades-long surgical career at Hammersmith Hospital, London.

The Welsh Blood Service is a division of Velindre University NHS Trust responsible for the collection of blood in Wales, and of the distribution of blood products to hospitals within the country, as well as other related functions.

Deutsche Knochenmarkspenderdatei, abbreviated as DKMS, is an international nonprofit bone marrow donor center based in Tübingen, Germany, with entities in Chile, India, Poland, South Africa, the United Kingdom and the United States. DKMS works in the areas of blood cancer and hematopoietic stem cell transplantation and raises awareness of the need for donors for hematopoietic stem cell transplantation which people with blood cancers need for treatment as well as helping people sign up to their national bone marrow registries. Over the years, DKMS has expanded beyond Germany.

Amal Bishara is an Israeli Arab doctor, and the director of Bone Marrow Registry Outreach, Hadassah Medical Center, which is associated with the Hebrew University of Jerusalem in Israel. There she runs the only bone marrow transplant registry in the world for unrelated Arab donors. Dr. Amal has published and presented internationally on her research into immunogenetics. She serves on the Accreditation Committee of the European Federation for Immunogenetics.

<span class="mw-page-title-main">DATRI</span> Nonprofit organization for blood stem cell donation in India

DATRI is a not-for-profit organization registered in 2009 as a Section 8 company under Government of India. DATRI is one of the largest unrelated blood stem cell donors registry in India, that helps patients with blood cancer and other fatal blood disorders to find a HLA matched Blood Stem Cell donor. Blood stem cell transplant is a chance of cure for patients with blood cancer and other severe blood disorders. As of January 2023, DATRI has more than 5 lakhs voluntary donors registered and it has facilitated 1074 plus transplants worldwide. DATRI operates across India.

<span class="mw-page-title-main">Shirley Nolan</span> Founded the worlds first bone marrow donor register (1942–2001)

Shirley Nolan or Shirley Oakey was a British teacher who set up the Anthony Nolan Register to allow Bone marrow transplants. Her son died and she was diagnosed with Parkinson disease taking her own life in 2001. The charity she founded made transplants possible for 4,000 people.

African Caribbean Leukaemia Trust (ACLT) is an independent UK charity for people with leukaemia and other life-threatening disorders. The ACLT aims to raise awareness on stem cell, blood and organ donation in the UK, with a particular focus on black and mixed race communities.

References

  1. ↑ "NHS BLOOD AND TRANSPLANT SEPTEMBER 2013" (PDF). NHS Blood & Transplant. Archived from the original (PDF) on 24 May 2014. Retrieved 23 May 2014.
  2. ↑ "What we do". AnthonyNolan.org. Archived from the original on 15 July 2010. Retrieved 30 July 2010.
  3. 1 2 3 4 "Our History". AnthonyNolan.org. Archived from the original on 15 July 2010. Retrieved 14 August 2020.
  4. 1 2 3 "Our History". Anthony Nolan. Retrieved 23 May 2014.
  5. ↑ "FAQs". Anthony Nolan. Retrieved 23 May 2014.
  6. ↑ "Marrow". AnthonyNolan.org. Retrieved 23 December 2015.
  7. ↑ "Anthony Nolan named as official charity partner for the 2014 London Marathon". Third Sector. 2013-04-23. Retrieved 23 May 2014.
  8. ↑ "Midland Metro". British Trams Online. Archived from the original on 6 October 2010. Retrieved 19 January 2022.
  9. ↑ Truman, Peter, "Leukaemia campaigner Daniel De Gale dies", Croydon Guardian, 9 October 2008; retrieved 18 February 2011.
  10. ↑ "Spit to save a life". AnthonyNolan.org. Archived from the original on 2013-12-03. Retrieved 11 March 2013.
  11. ↑ "MEET OUR NEW PATRON: OLIVIA COLMAN". Anthony Nolan. 2018-07-04. Retrieved 2019-02-18.
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