Bartonella elizabethae

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Bartonella elizabethae
Scientific classification OOjs UI icon edit-ltr.svg
Domain: Bacteria
Phylum: Pseudomonadota
Class: Alphaproteobacteria
Order: Hyphomicrobiales
Family: Bartonellaceae
Genus: Bartonella
Species:
B. elizabethae
Binomial name
Bartonella elizabethae
Daly et al., 1993

Bartonella elizabethae, formerly known as Rochalimaea elizabethae, is a bacterium in the genus Bartonella . [1] Like other Bartonella species, it causes the diseases bartonellosis.

Although the illnesses caused by Bartonella species other than the most common human pathogens — B. bacilliformis , B. quintana , and B. henselae — are not well-characterized individually, severe forms of bartonellosis present with endocarditis, lymphadenopathy, and neuroretinitis. [2] As with other Bartonella species, it can cause disease in animals, [3] and the reservoirs of B. elizabethae include dogs and rats.

B. elizabethae, like other rodent-borne Bartonella species, represents an emerging public health threat, especially in urban areas where rats are endemic. [4] Humans are an incidental host for the pathogen — direct transmission from dogs to humans is not well attested, and most human cases are contracted from ticks serving as a vector. [4] In cities, marginalized populations face greater risks: a 1992 study of the prevalence of bloodborne pathogens among homeless intravenous drug users in Los Angeles found an overall prevalence of 12.5% in this population. [5]

Related Research Articles

Trench fever is a moderately serious disease transmitted by body lice. It infected armies in Flanders, France, Poland, Galicia, Italy, Macedonia, Mesopotamia, Russia and Egypt in World War I. Three noted cases during WWI were the authors J. R. R. Tolkien, A. A. Milne, and C. S. Lewis. From 1915 to 1918 between one-fifth and one-third of all British troops reported ill had trench fever while about one-fifth of ill German and Austrian troops had the disease. The disease persists among the homeless. Outbreaks have been documented, for example, in Seattle and Baltimore in the United States among injection drug users and in Marseille, France, and Burundi.

<i>Bartonella henselae</i> Species of bacterium

Bartonella henselae, formerly Rochalimæa henselae, is a bacterium that is the causative agent of cat-scratch disease (bartonellosis).

Tick-borne diseases, which afflict humans and other animals, are caused by infectious agents transmitted by tick bites. They are caused by infection with a variety of pathogens, including rickettsia and other types of bacteria, viruses, and protozoa. The economic impact of tick-borne diseases is considered to be substantial in humans, and tick-borne diseases are estimated to affect ~80 % of cattle worldwide. Most of these pathogens require passage through vertebrate hosts as part of their life cycle. Tick-borne infections in humans, farm animals, and companion animals are primarily associated with wildlife animal reservoirs. Many tick-borne infections in humans involve a complex cycle between wildlife animal reservoirs and tick vectors. The survival and transmission of these tick-borne viruses are closely linked to their interactions with tick vectors and host cells. These viruses are classified into different families, including Asfarviridae, Reoviridae, Rhabdoviridae, Orthomyxoviridae, Bunyaviridae, and Flaviviridae.

<i>Bartonella</i> Genus of bacteria

Bartonella is a genus of Gram-negative bacteria. It is the only genus in the family Bartonellaceae. Facultative intracellular parasites, Bartonella species can infect healthy people, but are considered especially important as opportunistic pathogens. Bartonella species are transmitted by vectors such as fleas, sand flies, and mosquitoes. At least eight Bartonella species or subspecies are known to infect humans.

<span class="mw-page-title-main">Carrion's disease</span> Infectious disease caused by Bartonella bacilliformis

Carrion's disease is an infectious disease produced by Bartonella bacilliformis infection.

Bartonellosis is an infectious disease produced by bacteria of the genus Bartonella. Bartonella species cause diseases such as Carrión's disease, trench fever, cat-scratch disease, bacillary angiomatosis, peliosis hepatis, chronic bacteremia, endocarditis, chronic lymphadenopathy, and neurological disorders.

Bartonella rochalimae is a recently discovered strain of Gram-negative bacteria in the genus Bartonella, isolated by researchers at the University of California, San Francisco (UCSF), Massachusetts General Hospital, and the United States Centers for Disease Control and Prevention. The bacterium is a close relative of Bartonella quintana, the microbe which caused trench fever in thousands of soldiers during World War I. Named after Brazilian scientist Henrique da Rocha Lima, B. rochalimae is also closely related to Bartonella henselae, a bacterium identified in the mid-1990s during the AIDS epidemic in San Francisco as the cause of cat scratch fever, which still infects more than 24,000 people in the United States each year.

Bartonella quintana, originally known as Rochalimaea quintana, and "Rickettsia quintana", is a bacterium transmitted by the human body louse that causes trench fever. This bacterial species caused outbreaks of trench fever affecting 1 million soldiers in Europe during World War I.

Rickettsia typhi is a small, aerobic, obligate intracellular, rod shaped gram negative bacterium. It belongs to the typhus group of the Rickettsia genus, along with R. prowazekii. R. typhi has an uncertain history, as it may have long gone shadowed by epidemic typhus. This bacterium is recognized as a biocontainment level 2/3 organism. R. typhi is a flea-borne disease that is best known to be the causative agent for the disease murine typhus, which is an endemic typhus in humans that is distributed worldwide. As with all rickettsial organisms, R. typhi is a zoonotic agent that causes the disease murine typhus, displaying non-specific mild symptoms of fevers, headaches, pains and rashes. There are two cycles of R. typhi transmission from animal reservoirs containing R. typhi to humans: a classic rat-flea-rat cycle that is most well studied and common, and a secondary periodomestic cycle that could involve cats, dogs, opossums, sheep, and their fleas.

<span class="mw-page-title-main">BH11960</span>

Bartonella henselae hypothetical protein 11960 (BH11960) is encoded by the BH11960 gene. This hypothetical protein is conserved in all Bartonella species whose genomes have been sequenced to date, and are highlighted in the picture below.

<span class="mw-page-title-main">Cat-scratch disease</span> Human disease

Cat-scratch disease (CSD) is an infectious disease that most often results from a scratch or bite of a cat. Symptoms typically include a non-painful bump or blister at the site of injury and painful and swollen lymph nodes. People may feel tired, have a headache, or a fever. Symptoms typically begin within 3–14 days following infection.

Corynebacterium amycolatum is a gram-positive, non-spore-forming, aerobic or facultatively anaerobic bacillus capable of fermentation with propionic acid as the major end product of its glucose metabolism. One of its best known relatives is Corynebacterium diphtheriae, the causative agent of diphtheria. C. amycolatum is a common component of the natural flora found on human skin and mucous membranes, and therefore is an occasional contaminant in human blood cultures but can rarely cause infections such as endocarditis.

Bartonella alsatica is a bacterium. Like other Bartonella species, it can cause disease in animals. It is small, aerobic, oxidase-negative, and Gram-negative. Its rod-like cells were localized within wild rabbit erythrocytes when first described. The type strain is IBS 382T. It is associated with cases of lymphadenitis and endocarditis.

Staphylococcus schleiferi is a Gram-positive, cocci-shaped bacterium of the family Staphylococcaceae. It is facultatively anaerobic, coagulase-variable, and can be readily cultured on blood agar where the bacterium tends to form opaque, non-pigmented colonies and beta (β) hemolysis. There exists two subspecies under the species S. schleiferi: Staphylococcus schleiferi subsp. schleiferi and Staphylococcus schleiferi subsp. coagulans.

Bartonella koehlerae is a bacterium first isolated from cats. Its genome consists of 1.7–1.8 Mb.

Bartonella clarridgeiae is a Gram-negative bacteria from the genus Bartonella which was first isolated in the United States. Bartonella clarridgeiae is a zoonotic pathogen which can cause cat scratch disease.

Bartonella vinsonii is a gram-negative bacteria from the genus Bartonella which was isolated from dogs. Rochalimaea vinsonii was reclassified to Bartonella vinsonii. B. vinsonii contains three validly published subspecies B. vinsonii subsp. arupensis, B. vinsonii subsp. berkhoffii, and B. vinsonii subsp. vinsonii, and one effectively published B. vinsonii subsp. yucatanensis. B. vinsonii subsp. vinsonii has been isolated from voles and B. vinsonii subsp. berkhofli was isolated from a dog with endocarditis. B. vinsonii subsp. berkhoffii can cause diseases in humans. Those two subspecies are named after J. William Vinson and Herman A. Berkhoff.

Bartonella tamiae is a Gram-negative, rod-shaped bacteria from the genus Bartonella which was isolated from the blood of patients in Thailand. Bartonella tamiae can cause illness in humans.

Bartonella washoensis is a bacterium from the genus Bartonella which was first isolated from a dog with mitral valve endocarditis. Bartonella washoensis can infect squirrels but also can cause meningitis in humans.

Neoehrlichia mikurensis (NM), previously known as Candidatus Neoehrlichia mikurensis, is an intracellular, gram-negative bacteria belonging to the family Anaplasmataceae. Using ticks as vectors, it spreads between animals - mainly rodents, but other mammals as well as humans can get infected. After Borrelia and Rickettsia, it is believed to be the third most common tick-borne pathogen able to infect humans. Between 2009 and 2019, 45 human cases of NM-infections were found in Sweden.

References

  1. Daly JS, Worthington MG, Brenner DJ, Moss CW, Hollis DG, Weyant RS, et al. (April 1993). "Rochalimaea elizabethae sp. nov. isolated from a patient with endocarditis". Journal of Clinical Microbiology. 31 (4): 872–881. doi:10.1128/JCM.31.4.872-881.1993. PMC   263580 . PMID   7681847.
  2. Krügel M, Król N, Kempf VA, Pfeffer M, Obiegala A (March 2022). "Emerging rodent-associated Bartonella: a threat for human health?". Parasites & Vectors. 15 (1): 113. doi: 10.1186/s13071-022-05162-5 . PMC   8969336 . PMID   35361285.
  3. Mexas AM, Hancock SI, Breitschwerdt EB (December 2002). "Bartonella henselae and Bartonella elizabethae as potential canine pathogens". Journal of Clinical Microbiology. 40 (12): 4670–4674. doi:10.1128/jcm.40.12.4670-4674.2002. PMC   154595 . PMID   12454170.
  4. 1 2 Cheslock MA, Embers ME (April 2019). "Human Bartonellosis: An Underappreciated Public Health Problem?". Tropical Medicine and Infectious Disease. 4 (2): 69. doi: 10.3390/tropicalmed4020069 . PMC   6630881 . PMID   31010191.
  5. Smith HM, Reporter R, Rood MP, Linscott AJ, Mascola LM, Hogrefe W, et al. (December 2002). "Prevalence study of antibody to ratborne pathogens and other agents among patients using a free clinic in downtown Los Angeles". The Journal of Infectious Diseases. 186 (11): 1673–1676. doi: 10.1086/345377 . PMID   12447746.