Catechol 2,3-dioxygenase

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Catechol 2,3-dioxygenase
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Catechol 2,3-dioxygenase tetramer, Pseudomonas alkylphenolica
Identifiers
EC no. 1.13.11.2
CAS no. 9029-46-3
Databases
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MetaCyc metabolic pathway
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Catechol 2,3-dioxygenase (EC 1.13.11.2, 2,3-pyrocatechase, catechol 2,3-oxygenase, catechol oxygenase, metapyrocatechase, pyrocatechol 2,3-dioxygenase) is an enzyme with systematic name catechol:oxygen 2,3-oxidoreductase (decyclizing). [1] [2] [3] [4] [5] This enzyme catalyses the following chemical reaction

Brenzcatechin.svg
catechol
 
O2
 
Catechol 2,3-dioxygenase
O2
 
 
(2E,4Z)-2-hydroxy-6-oxohexa-2,4-dienoic acid.svg
(2E,4Z)-2-hydroxy-6-oxohexa-2,4-dienoic acid

This enzyme contains Fe(II). [6]

References

  1. ↑ Junker F, Field JA, Bangerter F, Ramsteiner K, Kohler HP, Joannou CL, Mason JR, Leisinger T, Cook AM (June 1994). "Oxygenation and spontaneous deamination of 2-aminobenzenesulphonic acid in Alcaligenes sp. strain O-1 with subsequent meta ring cleavage and spontaneous desulphonation to 2-hydroxymuconic acid". The Biochemical Journal. 300 ( Pt 2) (2): 429–36. doi:10.1042/bj3000429. PMC   1138180 . PMID   8002948.
  2. ↑ Junker F, Leisinger T, Cook AM (July 1994). "3-Sulphocatechol 2,3-dioxygenase and other dioxygenases (EC 1.13.11.2 and EC 1.14.12.-) in the degradative pathways of 2-aminobenzenesulphonic, benzenesulphonic and 4-toluenesulphonic acids in Alcaligenes sp. strain O-1". Microbiology. 140 ( Pt 7) (7): 1713–22. doi: 10.1099/13500872-140-7-1713 . PMID   8075807.
  3. ↑ Hayaishi O, Lardy H, Myrbäck K (1963). "Direct oxygenation by O2, oxygenases". In Boyer PD (ed.). The Enzymes. Vol. 8 (2nd ed.). New York: Academic Press. pp. 353–371.
  4. ↑ Kojima Y, Itada N, Hayaishi O (August 1961). "Metapyrocatachase: a new catechol-cleaving enzyme". The Journal of Biological Chemistry. 236 (8): 2223–8. doi: 10.1016/S0021-9258(18)64061-X . PMID   13757654.
  5. ↑ Nozaki M, Kagamiyama H, Hayaishi O (1963). "Metapyrocatechase. I. Purification, Crystallization and Some Properties". Biochemische Zeitschrift. 338: 582–90. PMID   14087325.
  6. ↑ Enzyme 1.13.11.2 at KEGG Pathway Database.
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