| Corydalis ambigua | |
|---|---|
 | |
Scientific classification  | |
| Kingdom: | Plantae |
| Clade: | Tracheophytes |
| Clade: | Angiosperms |
| Clade: | Eudicots |
| Order: | Ranunculales |
| Family: | Papaveraceae |
| Genus: | Corydalis |
| Species: | C. ambigua |
| Binomial name | |
| Corydalis ambigua | |
Corydalis ambigua is a tuberous early flowering east Asian flowering plant species in the poppy family Papaveraceae. Its exact native range is obscure due to taxonomic confusion. [1] It is one of the sources of the drug tetrahydropalmatine.
Corydalis ambigua contains a variety of alkaloids including corynoline, acetylcorynoline, d-corydalin, dl-tetrahydropalmatine, protopine, tetrahydrocoptisine, dl-tetrahydrocoptisine, d-corybulbine and allocryptopine. [2] [3] [4] [5]
Chemical derivatives of tetrahydroprotoberberines present in Corydalis ambigua have been studied as potential ways to increase pain tolerance and for treating drug addiction. [6] Further, they may represent a category of neurotransmitter stabilizers which have potential use in broad range of psychotic and neurological disorders. [6]
Cordyalis ambigua is part of the traditional Ainu cuisine:
The bulbs of this plant are extensively eaten by the Ainu, especially by those in the Ishikari valley, Saghalien, and Southern Kuriles. The bulb has a slightly bitter taste, which is removed by repeated boilings in water. In Etorup, the Ainu boil with a certain kind of earth to remove its bitterness. They are eaten either simply boiled or mixed with rice. In Saghalien, it is said that they are cooked generally with the fat of seals. The bulbs are often boiled and then dried for future use. [7]
The Papaveraceae are an economically important family of about 42 genera and approximately 775 known species of flowering plants in the order Ranunculales, informally known as the poppy family. The family is cosmopolitan, occurring in temperate and subtropical climates, but almost unknown in the tropics. Most are herbaceous plants, but a few are shrubs and small trees. The family currently includes two groups that have been considered to be separate families: Fumariaceae and Pteridophyllaceae.
Solanine is a glycoalkaloid poison found in species of the nightshade family within the genus Solanum, such as the potato, the tomato, and the eggplant. It can occur naturally in any part of the plant, including the leaves, fruit, and tubers. Solanine has pesticidal properties, and it is one of the plant's natural defenses. Solanine was first isolated in 1820 from the berries of the European black nightshade, after which it was named. It belongs to the chemical family of saponins.
Ainu cuisine is the cuisine of the ethnic Ainu in Japan and Russia. The cuisine differs markedly from that of the majority Yamato people of Japan. Raw meat like sashimi, for example, is rarely served in Ainu cuisine, which instead uses methods such as boiling, roasting and curing to prepare meat. Also unlike Japanese cuisine, traditional Ainu cuisine did not use miso, soy sauce, or sugar, though these seasonings make an appearance in modern Ainu cuisine. The island of Hokkaidō in northern Japan is where most Ainu live today; however, they once inhabited most of the Kuril islands, the southern half of Sakhalin island, and parts of northern Honshū Island.
Yam is the common name for some plant species in the genus Dioscorea that form edible tubers.
Lupin or lupini are the yellow legume seeds of the genus Lupinus. They are traditionally eaten as a pickled snack food, primarily in the Mediterranean basin, Latin America and North Africa. The most ancient evidence of lupin is from ancient Egypt, dating back to the 22nd century BCE. The bitter variety of the beans are high in alkaloids and are extremely bitter unless rinsed methodically. Low alkaloid cultivars called sweet lupins have been bred, and are increasingly planted.
Phellodendron amurense is a species of tree in the family Rutaceae, commonly called the Amur cork tree. It is a major source of huáng bò, one of the 50 fundamental herbs used in traditional Chinese medicine. The Ainu people used this plant, called shikerebe-ni, as a painkiller. It is known as hwangbyeok in Korean and (キハダ) kihada in Japanese.
Scoulerine, also known as discretamine and aequaline, is a benzylisoquinoline alkaloid (BIA) that is derived directly from (S)-reticuline through the action of berberine bridge enzyme. It is a precursor of other BIAs, notably berberine, noscapine, (S)-tetrahydropalmatine, and (S)-stylopine, as well as the alkaloids protopine, and sanguinarine. It is found in many plants, including opium poppy, Croton flavens, and certain plants in the genus Erythrina.
Petasites japonicus, also known as butterbur, giant butterbur, great butterbur and sweet-coltsfoot, is an herbaceous perennial plant in the family Asteraceae. It is native to China, Japan, Korea and Sakhalin and introduced in Europe and North America. It was introduced to southern British Columbia in Canada by Japanese migrants.
Bulbocapnine is an alkaloid found in Corydalis and Dicentra, genera of the plant family Fumariaceae which have caused the fatal poisoning of sheep and cattle. It has been shown to act as an acetylcholinesterase inhibitor, and inhibits biosynthesis of dopamine via inhibition of the enzyme tyrosine hydroxylase. Like apomorphine, it is reported to be an inhibitor of amyloid beta protein (Aβ) fiber formation, whose presence is a hallmark of Alzheimer's disease (AD). Bulbocapnine is thus a potential therapeutic under the amyloid hypothesis. According to the Dorlands Medical Dictionary, it "inhibits the reflex and motor activities of striated muscle. It has been used in the treatment of muscular tremors and vestibular nystagmus".
Erythrina fusca is a species of flowering tree in the legume family, Fabaceae. It is known by many common names, including purple coraltree, gallito, bois immortelle, bucayo, and the more ambiguous "bucare" and "coral bean". E. fusca has the widest distribution of any Erythrina species; it is the only one found in both the New and Old World. It grows on coasts and along rivers in tropical Asia, Oceania, the Mascarene Islands, Madagascar, Africa, and the Neotropics.
Zephyranthes robusta, synonym Habranthus robustus, commonly known as the Brazilian copperlily, pink fairy lily or the pink rain lily, is a species of herbaceous flowering bulb. It is native to Brazil, Argentina and Uruguay, but is now naturalized in Florida, Colombia, South Africa, and Mauritius.
Dichroa febrifuga is a flowering plant in the family Hydrangeaceae.
Tetrahydropalmatine (THP) is an isoquinoline alkaloid found in several different plant species, mainly in the genus Corydalis, but also in other plants such as Stephania rotunda. These plants have traditional uses in Chinese herbal medicine. The pharmaceutical industry has synthetically produced the more potent enantiomer Levo-tetrahydropalmatine (Levo-THP), which has been marketed worldwide under different brand names as an alternative to anxiolytic and sedative drugs of the benzodiazepine group and analgesics such as opiates. It is also sold as a dietary supplement.
(−)-Stepholidine is a protoberberine alkaloid found in the plant Stephania intermedia.
Nantenine is an alkaloid found in the plant Nandina domestica as well as some Corydalis species. It is an antagonist of both the α1-adrenergic receptor and the serotonin 5-HT2A receptor, and blocks both the behavioral and physiological effects of MDMA in animals.
Protopine is an alkaloid occurring in opium poppy, Corydalis tubers and other plants of the family papaveraceae, like Fumaria officinalis. Protopine is metabolically derived from the benzylisoquinoline alkaloid (S)-Reticuline through a progressive series of five enzymatic transformations: 1) berberine bridge enzyme to (S)-Scoulerine; 2) (S)-cheilanthifoline synthase/CYP719A25 to (S)-Cheilanthifoline; 3) (S)-stylopine synthase/CYP719A20 to (S)-Stylopine; 4) (S)-tetrahydroprotoberberine N-methyltransferase to (S)-cis-N-Methylstylopine; and ultimately, 5) N-methylstylopine hydroxylase to protopine.
Biomphalaria tenagophila is a species of air-breathing freshwater snail, an aquatic pulmonate gastropod mollusk in the family Planorbidae, the ram's horn snails.
Antonia is a plant genus in the family Loganiaceae.
Crinum macowanii is a species of flowering plant in the Amaryllidaceae family. It is a deciduous bulbous plant species native to Africa that has been used in traditional medicine throughout southern Africa.
Corydalis filistipes is a perennial flowering plant in the family Papaveraceae. It is found only on Ulleung Island in North Gyeongsang Province, South Korea. It is listed as vulnerable on the IUCN Red List of Threatened Species.
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