Crotalus durissus cumanensis

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Crotalus durissus cumanensis
Crotalus durissus cumanensis DT -CO Pereira Zoo- (1) (20742985515).jpg
Scientific classification OOjs UI icon edit-ltr.svg
Domain: Eukaryota
Kingdom: Animalia
Phylum: Chordata
Class: Reptilia
Order: Squamata
Suborder: Serpentes
Family: Viperidae
Genus: Crotalus
Species:
Subspecies:
C. d. cumanensis
Trinomial name
Crotalus durissus cumanensis
Humboldt, 1833

Crotalus durissus cumanensis is a subspecies of venomous pit viper from Colombia and Venezuela. [1] They account for 1-3% of all snake bites in Colombia. [2] [3] [4]

Toxin

A bite from Crotalus durissus cumanensis can cause neurotoxicity, systemic myotoxicity, mild edema, acute renal failure and death, [2] [5] even considered one of the most lethal snake species in Latin America. [6] These bites are only treatable as of now by antivenom therapy. [3] The toxin is thought to be more potent than that of Crotalus durissus ruruima . [7]

Related Research Articles

<span class="mw-page-title-main">Venom</span> Toxin secreted by an animal

Venom or zootoxin is a type of toxin produced by an animal that is actively delivered through a wound by means of a bite, sting, or similar action. The toxin is delivered through a specially evolved venom apparatus, such as fangs or a stinger, in a process called envenomation. Venom is often distinguished from poison, which is a toxin that is passively delivered by being ingested, inhaled, or absorbed through the skin, and toxungen, which is actively transferred to the external surface of another animal via a physical delivery mechanism.

<span class="mw-page-title-main">Antivenom</span> Medical treatment for venomous bites and stings

Antivenom, also known as antivenin, venom antiserum, and antivenom immunoglobulin, is a specific treatment for envenomation. It is composed of antibodies and used to treat certain venomous bites and stings. Antivenoms are recommended only if there is significant toxicity or a high risk of toxicity. The specific antivenom needed depends on the species involved. It is given by injection.

<span class="mw-page-title-main">Rattlesnake</span> Group of venomous snakes of the genera Crotalus and Sistrurus

Rattlesnakes are venomous snakes that form the genera Crotalus and Sistrurus of the subfamily Crotalinae. All rattlesnakes are vipers. Rattlesnakes are predators that live in a wide array of habitats, hunting small animals such as birds and rodents.

<span class="mw-page-title-main">Snakebite</span> Injury caused by bite from snakes

A snakebite is an injury caused by the bite of a snake, especially a venomous snake. A common sign of a bite from a venomous snake is the presence of two puncture wounds from the animal's fangs. Sometimes venom injection from the bite may occur. This may result in redness, swelling, and severe pain at the area, which may take up to an hour to appear. Vomiting, blurred vision, tingling of the limbs, and sweating may result. Most bites are on the hands, arms, or legs. Fear following a bite is common with symptoms of a racing heart and feeling faint. The venom may cause bleeding, kidney failure, a severe allergic reaction, tissue death around the bite, or breathing problems. Bites may result in the loss of a limb or other chronic problems or even death.

<span class="mw-page-title-main">Snake venom</span> Highly modified saliva containing zootoxins

Snake venom is a highly toxic saliva containing zootoxins that facilitates in the immobilization and digestion of prey. This also provides defense against threats. Snake venom is usually injected by unique fangs during a bite, though some species are also able to spit venom.

<i>Crotalus scutulatus</i> Species of snake

Crotalus scutulatus is known commonly as the Mohave Rattlesnake. Other common English names include Mojave Rattlesnake and, referring specifically to the nominate (northern) subspecies: Northern Mohave Rattlesnake and Mojave Green Rattlesnake, the latter name commonly shortened to the more colloquial “Mojave green”. Campbell and Lamar (2004) supported the English name “Mohave (Mojave) rattlesnake” with some reluctance because so little of the snake’s range lies within the Mojave Desert.

<span class="mw-page-title-main">Convulxin</span> Snake venom toxin

Convulxin is a snake venom toxin found in a tropical rattlesnake known as Crotalus durissus terrificus. It belongs to the family of hemotoxins, which destroy red blood cells or, as is the case with convulxin, induce blood coagulation.

<span class="mw-page-title-main">Myotoxin</span>

Myotoxins are small, basic peptides found in snake venoms and lizard venoms. This involves a non-enzymatic mechanism that leads to severe muscle necrosis. These peptides act very quickly, causing instantaneous paralysis to prevent prey from escaping and eventually death due to diaphragmatic paralysis.

<i>Daboia palaestinae</i> Species of snake

Daboia palaestinae, also known as the Palestine viper, is a viper species endemic to the Levant. Like all vipers, it is venomous. It is considered a leading cause of snakebite within its range. No subspecies are currently recognized.

<span class="mw-page-title-main">Venomous fish</span> Fish that have the ability to produce toxins

Venomous fish are species of fish which produce strong mixtures of toxins harmful to humans which they deliberately deliver by means of a bite, sting, or stab, resulting in an envenomation. As a contrast, poisonous fish also produce a strong toxin, but they do not bite, sting, or stab to deliver the toxin, instead being poisonous to eat because the human digestive system does not destroy the toxin they contain in their bodies. Venomous fish do not necessarily cause poisoning if they are eaten, as the digestive system often destroys the venom.

<i>Crotalus durissus</i> Species of snake

Crotalus durissus, known as the South American rattlesnake, tropical rattlesnake, and by other names, is a highly venomous pit viper species found in South America. It is the most widely distributed member of its genus. Currently, seven subspecies are recognized.

<span class="mw-page-title-main">Crotamine</span>

Crotamine is a toxin present in the venom of the South American rattlesnake. It is a 42-residue-long protein containing 11 basic residues and six cysteines. It has also been isolated from the venom of North American prairie rattlesnake, Crotalus viridis viridis. It was first isolated and purified by Brazilian scientist José Moura Gonçalves, and later intensively studied by his group of collaborators at the Medical School of Ribeirão Preto of the University of São Paulo.

<i>Crotalus concolor</i> Species of snake

Crotalus concolor, commonly known as the midget faded rattlesnake, faded rattlesnake, and yellow rattlesnake, is a pit viper species found in the western United States. It is a small rattlesnake known for its faded color pattern. Like all other pit vipers, it is venomous.

<span class="mw-page-title-main">Snake antivenom</span> Medication used to treat bites by venomous snakes

Snake antivenom is a medication made up of antibodies used to treat snake bites by venomous snakes. It is a type of antivenom.

Mipartoxin-I is a neurotoxin produced by Micrurus mipartitus, a venomous coral snake distributed in Central and South America. This toxin causes a neuromuscular blockade by blocking the nicotinic acetylcholine receptor. It is the most abundant component in the venom.

The whole blood clotting test is a blood test used to check the coagulation mechanism in the blood following a snake bite. If the test is positive after a bite in South East Asia it indicates the snake was a viper rather than an elapid. It can also be used to assess the effectiveness of antivenin therapy.

Crotoxin (CTX) is the main toxic compound in the snake venom of the South American rattlesnake, Crotalus durissus terrificus. Crotoxin is a heterodimeric beta-neurotoxin, composed of an acidic, non-toxic and non-enzymatic subunit (CA), and a basic, weakly toxic, phospholipase A2 protein (CB). This neurotoxin causes paralysis by both pre- and postsynaptic blocking of acetylcholine signalling.

<i>Tityus pachyurus</i> Species of scorpion

Tityus pachyurus is a species of arachnid endemic to Central America and South America.

Venomics is the study of proteins associated with venom, a toxic substance secreted by animals, which is typically injected either offensively or defensively into prey or aggressors, respectively.

References

  1. Salazar, Ana M; Aguilar, Irma; Guerrero, Belsy; Girón, María E; Lucena, Sara; Sánchez, Elda E; Rodríguez-Acosta, Alexis (September 2008). "Intraspecies differences in hemostatic venom activities of the South American rattlesnakes, Crotalus durissus cumanensis, as revealed by a range of protease inhibitors". Blood Coagulation & Fibrinolysis. 19 (6): 525–530. doi:10.1097/MBC.0b013e328304e02e. ISSN   0957-5235. PMID   18685436.
  2. 1 2 Pereañez, Jaime Andrés; Núñez, Vitelbina; Huancahuire-Vega, Salomón; Marangoni, Sergio; Ponce-Soto, Luis Alberto (2009-04-01). "Biochemical and biological characterization of a PLA2 from crotoxin complex of Crotalus durissus cumanensis". Toxicon. 53 (5): 534–542. doi:10.1016/j.toxicon.2009.01.021. ISSN   0041-0101. PMID   19673100.
  3. 1 2 Rodríguez-Vargas, Ariadna; Vega, Nohora; Reyes-Montaño, Edgar; Corzo, Gerardo; Neri-Castro, Edgar; Clement, Herlinda; Ruiz-Gómez, Francisco (August 2022). "Intraspecific Differences in the Venom of Crotalus durissus cumanensis from Colombia". Toxins. 14 (8): 532. doi: 10.3390/toxins14080532 . ISSN   2072-6651. PMC   9416679 . PMID   36006194.
  4. Acosta-Peña, Augusto; Núñez, Vitelbina; Pereañez, Jaime Andres; Rey-Suárez, Paola (April 2022). "Immunorecognition and Neutralization of Crotalus durissus cumanensis Venom by a Commercial Antivenom Produced in Colombia". Toxins. 14 (4): 235. doi: 10.3390/toxins14040235 . ISSN   2072-6651. PMC   9025410 . PMID   35448844.
  5. Yoshida-Kanashiro, Erika; Navarrete, Luis F.; Rodríguez-Acosta, Alexis (April 2003). "On the unsual [sic] hemorrhagic and necrotic activities caused by the rattlesnake (Crotalus durissus cumanensis) in a Venezuelan patient". Revista Cubana de Medicina Tropical. 55 (1): 38–40. ISSN   0375-0760. PMID   15849951.
  6. Céspedes, N.; Castro, F.; Jiménez, E.; Montealegre, L.; Castellanos, A.; Cañas, C. A.; Arévalo-Herrera, M.; Herrera, S. (2010). "Biochemical comparison of venoms from young Colombian Crotalus durissus cumanensis and their parents". Journal of Venomous Animals and Toxins Including Tropical Diseases. 16 (2): 268–284. doi: 10.1590/S1678-91992010000200009 . ISSN   1678-9199.
  7. Cavalcante, Walter Luís Garrido; Ponce-Soto, Luis Alberto; Marangoni, Sérgio; Gallacci, Márcia (2015-03-15). "Neuromuscular effects of venoms and crotoxin-like proteins from Crotalus durissus ruruima and Crotalus durissus cumanensis". Toxicon. 96: 46–49. Bibcode:2015Txcn...96...46C. doi:10.1016/j.toxicon.2015.01.006. ISSN   0041-0101. PMID   25598498.