Haplogroup A-P305

Last updated
Haplogroup A1
Possible time of origin161,300 years BP [1]
Possible place of origin Africa
Ancestor A0-T
Descendants A1a and A1b
Defining mutationsP305

Haplogroup A-P305 also known as A1 is a human Y-chromosome DNA haplogroup. Like its parent haplogroup haplogroup A0-T (A-L1085), A1 includes the vast majority of living human males. It emerged in Africa approximately 161,300 years ago. [1] By comparison, members of its sole sibling subclade, haplogroup A0 – the only other primary subclade of haplogroup A0-T – are found mostly in Africa.

Basal, undivergent A-P305* is largely restricted to populations native to Africa, though a handful of cases have been reported in Europe and Western Asia. A-P305* is found at its highest rates in Bakola Pygmies (South Cameroon) at 8.3% and Berbers from Tunisia at 1.5% [2] and in Ghana. [3] The clade also achieves high frequencies in the Bushmen hunter-gatherer populations of Southern Africa, followed closely by many Nilotic groups in Eastern Africa. However, haplogroup A's oldest sub-clades are exclusively found in Central-Northwest Africa, where it, and consequently Y-chromosomal Adam, is believed to have originated about 140,000 years ago. [2] The clade has also been observed at notable frequencies in certain populations in Ethiopia, as well as some Pygmy groups in Central Africa.

Footnotes

  1. 1 2 "A1 YTree". www.yfull.com.
  2. 1 2 Cruciani F, Trombetta B, Massaia A, Destro-Bisol G, Sellitto D, Scozzari R (Jun 2011). "A revised root for the human Y chromosomal phylogenetic tree: the origin of patrilineal diversity in Africa". American Journal of Human Genetics. 88 (6): 814–8. doi:10.1016/j.ajhg.2011.05.002. PMC   3113241 . PMID   21601174.
  3. Scozzari R, Massaia A, D'Atanasio E, et al. (2012). "Molecular dissection of the basal clades in the human Y chromosome phylogenetic tree". PLOS ONE. 7 (11): e49170. Bibcode:2012PLoSO...749170S. doi: 10.1371/journal.pone.0049170 . PMC   3492319 . PMID   23145109.
Phylogenetic tree of human Y-chromosome DNA haplogroups [χ 1] [χ 2]
"Y-chromosomal Adam"
A00 A0-T   [χ 3]
A0 A1   [χ 4]
A1a A1b
A1b1 BT
B CT
DE CF
D E C F
F1   F2   F3   GHIJK
G HIJK
IJK H
IJ K
I    J      LT   [χ 5]        K2   [χ 6]
L      T     K2a   [χ 7]         K2b   [χ 8]      K2c      K2d K2e   [χ 9]   
K-M2313   [χ 10]      K2b1   [χ 11] P   [χ 12]
NO    S   [χ 13]   M   [χ 14]     P1      P2
N O Q R


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